Aptamer nucleotide analog drug conjugates in the targeting therapy of cancers by Yongshu Li, Yongshu Li, Yongshu Li, Jing Zhao, Zhichao Xue, Chiman Tsang, Xiaoting Qiao, Lianhua Dong, Lianhua Dong, Huijie Li, Yi Yang, Bin Yu, Yunhua Gao, Yunhua Gao

Subjects: Get full text

Role of novel and rare nucleotide substitutions of the β-globin gene by Margherita Vinciguerra, Monica Cannata, Filippo Cassarà, Pina Lo Gioco, Filippo Leto, Cristina Passarello, Antonino Giambona

Subjects: “…thalassemia, nucleotide substitutions, genetic counseling.…”
Get full text

Single Nucleotide Polymorphisms and Dental Fluorosis: A Systematic Review by Carlos González-Casamada, Martina Nevarez-Rascón, Alfredo Nevarez-Rascón, María González-Galván, Mario Alberto Isiordia-Espinoza, Ronell Bologna-Molina, Leonor Sánchez-Pérez, Nelly Molina-Frechero

“…The aim of this systematic review was to identify alleles/genotypes of single nucleotide polymorphisms (SNPs) associated with dental fluorosis (DF) and to identify them as protective or risk factors. …”
Get full text

Direct and indirect methods of determining DNA nucleotide sequences in microorganisms by R. A. Volkova, E. S. Skolotneva, E. V. Elbert, E. D. Mytsa, V. A. Merkulov, V. P. Bondarev, I. V. Borisevich

“…It can be obtained by either direct determination of genome sequences or by using a variety of techniques, that allow to indirectly assess the nucleotide composition in a representative genome locus of a microorganism under study. …”
Get full text

Studies on ATP-diphosphohydrolase nucleotide-binding sites by intrinsic fluorescence by A.M. Kettlun, V. Espinosa, A. Zanocco, M.A. Valenzuela

“…Differences in the nucleotide-binding site may explain, at least in part, the kinetic differences of the Pimpernel and Desirée isoapyrases.…”
Get full text

Single Nucleotide Polymorphisms Associated with Rheumatoid Arthritis in Saudi Patients by Maha Daghestani, Nashwa Othman, Mohammed A. Omair, Fahidah Alenzi, Maha A. Omair, Eman Alqurtas, Shireen Amin, Arjumand Warsy

Subjects: Get full text

The expanded development and application of CRISPR system for sensitive nucleotide detection by Fengjing Jia, Xuewen Li, Chao Zhang, Xueming Tang

Get full text

The effect of chlorination of nucleotide bases on the conformational properties of thymidine monophosphate by T. M. Mukhina, T. Yu. Nikolaienko

Subjects: Get full text

Stimuli-Responsive Nucleotide–Amino Acid Hybrid Supramolecular Hydrogels by Matthew Mulvee, Natasa Vasiljevic, Stephen Mann, Avinash J. Patil

Subjects: Get full text

The Single-Nucleotide Polymorphism (SNP) Validity to Detect Omicron Variants by Lia Gardenia Partakusuma, Luhung Budiailmiawan, null Budiman, Ida Parwati, null Aryati, Basti Andriyoko, Louisa Markus, Corine Niswara, Cut Nur Cinthia Alamanda

“…Hence, a faster and more accessible examination is needed. The single-nucleotide polymorphism (SNP) method is one of the options for genomic variation surveillance that can help provide an answer to this challenge. …”
Get full text

Phosphoramidate Azole Oligonucleotides for Single Nucleotide Polymorphism Detection by PCR by Alexey S. Chubarov, Elizaveta E. Baranovskaya, Igor P. Oscorbin, Ivan I. Yushin, Maxim L. Filipenko, Dmitrii V. Pyshnyi, Svetlana V. Vasilyeva, Alexander A. Lomzov

“…The most common <i>KRAS</i>-activating mutations are caused by single-nucleotide mutations, which are usually determined by using PCR, using allele-specific DNA primers. …”
Get full text

A Single Nucleotide Polymorphism Unique to the Galanthum-CMS of Onion by Michael J. Havey

“…In this research, a single nucleotide polymorphism unique to the cytoplasms of A. galanthum and Gal-CMS was identified, useful to distinguish Gal-CMS from other onion cytoplasms.…”
Get full text

Single nucleotide polymorphisms for parentage testing of horse breeds in Korea by Sun-Young Lee, Su-Min Kim, Baatartsogt Oyungerel, Gil-Jae Cho

Subjects: Get full text

Proteomics and Nucleotide Profiling as Tools for Biomarker and Drug Target Discovery by Bent Honoré, Gregory Edward Rice, Henrik Vorum

Get full text

Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics by Kirsten Voorhies, Joanne E. Sordillo, Michael McGeachie, Elizabeth Ampleford, Alberta L. Wang, Jessica Lasky-Su, Kelan Tantisira, Amber Dahlin, Rachel S. Kelly, Victor E. Ortega, Sharon M. Lutz, Ann C. Wu

“…The objective of this study was to identify whether age modifies genetic associations of single nucleotide polymorphisms (SNPs) with bronchodilator response (BDR) to β2-agonists. …”
Get full text

Evaluation of nucleotide MALDI-TOF-MS for the identification of Mycobacterium species by Yelei Zhu, Zhengwei Liu, Lina Peng, Bin Liu, Kunyang Wu, Mingwu Zhang, Xiaomeng Wang, Junhang Pan

Subjects: “…nucleotide MALDI-TOF-MS…”
Get full text

Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus by Quanyuan Wan, Leah Tavakoli, Ting-Yu Wang, Andrew J. Tucker, Ruiting Zhou, Qizhi Liu, Shu Feng, Dongwon Choi, Zhiheng He, Michaela U. Gack, Jun Zhao

“…Here we report that KSHV infection exploits CAD for nucleotide synthesis and glycolysis. Mechanistically, KSHV vCyclin binds to and hijacks cyclin-dependent kinase CDK6 to phosphorylate Ser-1900 on CAD, thereby activating CAD-mediated pyrimidine synthesis and RelA-deamidation-mediated glycolytic reprogramming. …”
Get full text

Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants by Griffin A. Welfer, Veniamin A. Borin, Luis M. Cortez, Patricia L. Opresko, Pratul K. Agarwal, Bret D. Freudenthal

“…Each variant had distinct consequences on tcTERT’s nucleotide insertion mechanism, including changes in nucleotide binding affinity, rates of catalysis, or ribonucleotide selectivity. …”
Get full text

Nucleotide Excision Repair: From Molecular Defects to Neurological Abnormalities by Yuliya Krasikova, Nadejda Rechkunova, Olga Lavrik

Subjects: “…nucleotide excision repair…”
Get full text

Achieving single nucleotide sensitivity in direct hybridization genome imaging by Yanbo Wang, W. Taylor Cottle, Haobo Wang, Momcilo Gavrilov, Roger S. Zou, Minh-Tam Pham, Srinivasan Yegnasubramanian, Scott Bailey, Taekjip Ha

“…Here the authors report single guide genome oligopaint via local denaturation fluorescence in situ hybridisation, sgGOLDFISH, a direct hybridisation genome imaging method with single-nucleotide sensitivity.…”
Get full text