Nucleus accumbens D1-receptors regulate and focus transitions to reward-seeking action by Grima, L, Panagi, M, Harmson, O, Syed, E, Manohar, S, Husain, M, Walton, M

“…Surprisingly, while after global D1R blockade this was characterized by a general retardation of reward-seeking actions, nucleus accumbens core (NAcC) D1R blockade had no effect on the speed of action initiation or impulsive actions. …”

MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro by F Woodward Hopf, Taban Seif, Shinjae Chung, Olivier Civelli

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Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation by Nan Dong, Nan Dong, Nan Dong, Jie Zhu, Jie Zhu, Rui Wang, Rui Wang, Shuai Wang, Shuai Wang, Yanjiong Chen, Changhe Wang, Eyleen L.K Goh, Eyleen L.K Goh, Teng Chen, Teng Chen

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Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking by Patrick J. Mulholland, Audrey E. Padula, Larry J. Wilhelm, Byung Park, Kathleen A. Grant, Betsy M. Ferguson, Rita Cervera-Juanes

“…Bisulfite sequencing analysis of the nucleus accumbens tissue from alcohol-drinking monkeys and alcohol-dependent mice revealed a differentially methylated region in exon 1A of KCNN3 that overlaps with a predicted promoter sequence. …”
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Nucleus Accumbens Chemogenetic Inhibition Suppresses Amphetamine-Induced Ultrasonic Vocalizations in Male and Female Rats by Kate A. Lawson, Abigail Y. Flores, Rachael E. Hokenson, Christina M. Ruiz, Stephen V. Mahler

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Compulsive methamphetamine taking in the presence of punishment is associated with increased oxytocin expression in the nucleus accumbens of rats by Irina N. Krasnova, Maria Carla Gerra, Donna Walther, Subramaniam Jayanthi, Bruce Ladenheim, Michael T. McCoy, Christie Brannock, Jean Lud Cadet

“…Rats were euthanized one day after the second extinction test and the nucleus accumbens (NAc) and dorsal striatum were collected to measure gene expression with microarray analysis. …”
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Endogenous opioids in the nucleus accumbens promote approach to high-fat food in the absence of caloric need by Kevin Caref, Saleem M Nicola

“…Consumption of such foods while calorically replete likely contributes to obesity. The nucleus accumbens (NAc) opioid system has long been viewed as a critical substrate for this behavior, mainly via contributions to the neural control of consumption and palatability. …”
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Deep Brain Stimulation of the Nucleus Accumbens in Severe Enduring Anorexia Nervosa: A Pilot Study by Jessica C. Scaife, Jessica C. Scaife, Jessica C. Scaife, John Eraifej, John Eraifej, Alexander L. Green, Alexander L. Green, Alexander L. Green, Beth Petric, Tipu Z. Aziz, Tipu Z. Aziz, Tipu Z. Aziz, Rebecca J. Park, Rebecca J. Park

“…Abnormal eating behavior and the compulsive pursuit of thinness in AN is, in part, a consequence of dysfunction in reward circuitry and the nucleus accumbens (NAcc) is central to reward processing.MethodsPhase 1 prospective open-label pilot study of seven individuals with severe enduring AN. …”
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Nucleus accumbens shell neurons’ early sensitivity to cocaine is associated with future increases in drug intake by Ashley K. Crawley, Anirudh Sharma, Kevin R. Coffey, Mark O. West, David J. Barker

“…We observed that the firing patterns of nucleus accumbens (NAc) core and shell neurons exhibited increasing sensitivity to cocaine over the first 6 S-A sessions and maintained a strong negative correlation between drug intake and neuronal firing rates across chronic S-A. …”
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The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal. by Mei-Hong Qiu, Wei Liu, Wei-Min Qu, Yoshihiro Urade, Jun Lu, Zhi-Li Huang

“…We proposed that the nucleus accumbens (NAc) that receives the ventral tegmental area dopamine inputs play an important role not only in reward and addiction but also in sleep-wake cycle and in mediating modafinil-induced arousal. …”
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A case of musical preference for Johnny Cash following deep brain stimulation of the nucleus accumbens by Mariska eMantione, Martijn eFigee, Damiaan eDenys

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IRAS/Nischarin modulates morphine reward by glutamate receptor activation in the nucleus accumbens of mouse brain by Shuo Li, Xiao-qin Zhang, Chuan-chuan Liu, Zhi-yuan Wang, Guan-yi Lu, Hao-wei Shen, Ning Wu, Jin Li, Fei Li

“…Conditional-knockout of IRAS in the nucleus accumbens (NAc) reproduced higher CPP, and overexpression of IRAS in the NAc rescued the increased morphine-induced CPP in IRAS-/- mice. …”
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The Effect of Nitric Oxide Microinjection in Nucleus Accumbens Shell on Morphine Withdrawal Signs in Male Rats by V Sheibani, Gh Sepehri, F Baghaiee, R Farazifard

Subjects: “…nucleus accumbens…”
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Glutamate Receptors in Nucleus Accumbens Can Modulate Canabinoid-Induced Antinociception in Rat’s Basolateral Amygdala by Mohadeseh Ghalandari-Shamami, Majid Hassanpour-Ezatti, Abbas Haghparast

Subjects: “…Nucleus accumbens…”
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Ginger Extract Reduces Chronic Morphine-Induced Neuroinflammation and Glial Activation in Nucleus Accumbens of Rats by Shima Torkzadeh-Mahani, Saeed Esmaeili-Mahani, Sima Nasri, Fatemeh Darvishzadeh, Reyhaneh Naderi

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Endocannabinoid-Mediated Plasticity in Nucleus Accumbens Controls Vulnerability to Anxiety after Social Defeat Stress by Clémentine Bosch-Bouju, Thomas Larrieu, Louisa Linders, Olivier J. Manzoni, Sophie Layé

“…Endocannabinoid-mediated spike-timing dependent plasticity (STDP) in the nucleus accumbens was attenuated in non-anxious mice and abolished in anxious mice. …”
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Deep brain stimulation response in obsessive–compulsive disorder is associated with preoperative nucleus accumbens volume by Luka C. Liebrand, Paul Zhutovsky, Eva K. Tolmeijer, Ilse Graat, Nienke Vulink, Pelle de Koning, Martijn Figee, P. Richard Schuurman, Pepijn van den Munckhof, Matthan W.A. Caan, Damiaan Denys, Guido A. van Wingen

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Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens by Ryan Kucera, Joseph Bouskila, Laurent Elkrief, Anders Fink-Jensen, Roberta Palmour, Jean-François Bouchard, Maurice Ptito

“…Abstract Extensive rodent literature suggests that the endocannabinoid (eCB) system present in the nucleus accumbens (NAc) modulates dopamine (DA) release in this area. …”
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The Role of eIF5A1 in LPS-Induced Neuronal Remodeling of the Nucleus Accumbens in the Depression by Qiang Lyu, Hecun Zou, Li Luo, Wei Liu, Xiang He, Fei-Fei Shang

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Differential phosphoproteome regulation of nucleus accumbens in environmentally enriched and isolated rats in response to acute stress. by Xiuzhen Fan, Dingge Li, Yafang Zhang, Thomas A Green

“…Thus, in this study, a phosphoproteomic approach was used to uncover differential phosphoprotein regulation in rat nucleus accumbens between isolated (IC) and enriched environmental conditions (EC) under basal conditions, and in response to acute stress. …”
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