Comparative proteomics reveals that YK51, a 4-Hydroxypandurantin-A analogue, downregulates the expression of proteins associated with dengue virus infection by Tan, Wei Lian, Lee, Yean Kee, Ho, Yen Fong, Yusof, Rohana, Abd Rahman, Noorsaadah, Karsani, Saiful Anuar

“…Our results suggested that apart from inhibiting the NS2B/NS3 DENV2 protease, YK51 may also be causing the down-regulation of a number of proteins that may be responsible in, and/or essential to virus infection. …”

Structural, optical and electrical properties of ZnO/ZnAl2O4 nanocomposites prepared via thermal reduction approach by Salih, Ethar Yahya, Sabri, Mohd Faizul Mohd, Hussein, Mohd Zobir, Sulaiman, Khaulah, Said, Suhana Mohd, Saifullah, Bullo, Bashir, Mohamed Bashir Ali

“…It is believed that the bathochromic shift in optical band gap of Z5A-MMO plays a pivotal role in facilitating the photoemission process and leads to the increase in number of carrier concentration in the sample. This method could provide alternative pathways for fabricating a high electrical conductivity MMO-based material and benefit in future optoelectronic devices.…”

Comparative efficacy of hemorrhage control of a novel mesoporous bioactive glass versus two commercial hemostats by Pourshahrestani, Sara, Kadri, Nahrizul Adib, Zeimaran, Ehsan, Gargiulo, Nicola, Samuel, Shani, Naveen, Sangeetha Vasudevaraj, Hasikin, Khairunnisa, Kamarul, Tunku, Towler, Mark Robert

“…The results indicate that the number of adherent platelets were higher on the 1%Ga-MBG and CX surfaces than ACS + whereas a greater contact activation was seen on 1%Ga-MBG and ACS + surfaces than CX. 1%Ga-MBG not only resulted in larger platelet aggregates and more extensive platelet pseudopodia compared to CX and ACS + but also significantly accelerated the intrinsic pathways of the clotting cascade. …”

RNA-Seq-mediated transcriptomic analysis of heat stress response in a polar Chlorella sp. (Trebouxiophyceae, Chlorophyta) by Poong, Sze Wan, Lee, Kok Keong, Lim, Phaik Eem, Pai, Tun Wen, Wong, Chiew Yen, Phang, Siew Moi, Chen, Chien Ming, Yang, Cing Han, Liu, Chun Cheng

“…A recent environmental report even postulated a high possibility of temperature increase of at least 3 °C by 2100. Despite the low number of human inhabitants in Antarctica, the Antarctic Peninsula was reported as one of the most rapidly warming locations on earth. …”

Numerical investigation for optimizing segmented micro-channel heat sink by Taguchi-Grey method by Naqiuddin, Nor Haziq, Saw, Lip Huat, Yew, Ming Chian, Yusof, Farazila, Poon, Hiew Mun, Cai, Zuansi, Thiam, Hui San

“…The effect of fin width, fin length, fin transverse distance, number of segments, channel width and mass flow rate on the specific performance, variation of temperature and pressure drop are investigated. …”

Post-war tourism as an urban reconstruction strategy case study: Khorramshahr by Mirisaee, Seyed Mehdi, Ahmad, Yahaya

“…Furthermore, data collection in the area located near the Iran-Iraq border (500 meters) presented a number of security caveats as limitations. Originality/value: The research found a majority of tourists and the residents preferred tourism zone where the combination of post-war and natural attraction across riverside area. …”

Simulation of improper food hygiene practices: A quantitative assessment of Vibrio parahaemolyticus distribution by Malcolm, Tan Turk Hsern, Chang, Wei San, Loo, Yuet Ying, Cheah, Yoke Kqueen, Wan Mohamed Radzi, Che Wan Jasimah, Kantilal, Haresh Kumar, Nishibuchi, Mitsuaki, Son, Radu

“…Kitchen mishandling practices contribute to a large number of foodborne illnesses. In this study, the transfer and cross-contamination potential of Vibrio parahaemolyticus from bloody clams to ready-to-eat food (lettuce) was assessed. …”

The journey of Malaysian NCVD-PCI (National Cardiovascular Disease Database-Percutaneous Coronary Intervention) Registry: A summary of three years report by Ahmad, W.A., Ali, R.M., Khanom, M., Han, C.K., Bang, L.H., Yip, A.F., Ghazi, A.M., Ismail, O., Zambahari, R., Hian, S.K.

“…Mean age of the patients was 57years and more than 98% of patients had at least one cardiovascular risk factor. A significant number of our patients were diabetic (50%) and had renal impairment (44.7% had≤stage 3 chronic kidney disease) at the time of procedure. …”

Seroprevalence of Q Fever Among the Indigenous People (Orang Asli) of Peninsular Malaysia by Khor, Chee Sieng, Mohd Rahim, Nurul Farhana, Hassan, Habibi, Chandren, Josephine Rebecca, Nore, Siti Sarah, Johari, Jefree, Loong, Shih Keng, Abd Jamil, Juraina, Khoo, Jing Jing, Lee, Hai Yen, Pike, Brian L., Wong, Li Ping, Lim, Yvonne Ai Lian, Zandi, Keivan, AbuBakar, Sazaly

“…Statistical methods were used to identify possible associations between seropositivity for C. burnetii and a number of demographic variables obtained from the questionnaires. …”

Comparative genomic analysis of ten clinical Streptococcus pneumoniae collected from a Malaysian hospital reveal 31 new unique drug-resistant SNPs using whole genome sequencing by Jindal, Hassan Mahmood, Ramanathan, Babu, Le, Cheng Foh, Gudimella, Ranganath, Razali, Rozaimi, Manikam, Rishya, Sekaran, Shamala Devi

“…Results: Our results showed that resistant isolates contain a higher number of non-synonymous single nucleotide polymorphisms (SNPs) as compared to susceptible isolates. …”

Development of an intelligent system based on ANFIS model for predicting soil erosion by Islam, Md Rabiul, Jaafar, Wan Zurina Wan, Lai, Sai Hin, Osman, Normaniza, Hossain, Anamul, Mohd, Nuruol Syuhadaa

“…Soft computing technique has been applied widely in various fields, but its application in soil science is limited. A number of models have been established in predicting soil erosion such as a revised universal soil loss equation (RUSLE) model whereby parameters of the RUSLE model are employed in testing the ANFIS model in this study. …”

Impact of pH on the viability and morphology of blastocystis isolates by Farah Haziqah, Meor Termizi, Chandrawathani, Panchacharam, Douadi, Benacer, Govind, Suresh Kumar, Wilson, John James, Mohd Khalid, Mohd Khairul Nizam, Rajamanikam, Arutchelvan, Lewis, John Watkin, Mohd Zain, Siti Nursheena

“…The use of Trypan blue showed that the number of viable cells increased when exposed to pH 4 and a significant increase in viability occurred in pH values of 5 to 7. …”

Prevalence of malnutrition and associated factors among community-dwelling older persons in Sri Lanka: a cross-sectional study by Damayanthi, Hewaratne Dassanayakege Wimala Thushari, Moy, Foong Ming, Abdullah, Khatijah Lim, Dharmaratne, Samath Dhamminda

“…In the multivariate model, hypertension (adjusted OR = 1.71; 95% CI: 1.02, 2.89), alcohol consumption (aOR = 4.06; 95% CI: 1.17, 14.07), and increased age (aOR = 1.06; 95% CI: 1.01, 1.11) were positively associated with malnutrition. An increased number of people living with the older person (aOR: 0.91; 95% CI: 0.85, 0.97) was a protective factor among those at risk for malnutrition. …”

Enriching student soft skills through compulsory university courses based on blended learning T&L by Alagappar, Ponmalar N., Che Husain, Faridah, Mat Noor, Noor Ain

“…From the total, only 232 forms were accepted and analysed for the pilot survey. This number was regarded adequate to test reliability and validity of the instrument. …”
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Transient receptor potential vanilloid 4 (TRPV4) expression on the nerve fibers of human dental pulp is upregulated under inflammatory condition by Bakri, Marina Mohd, Yahya, Farhana, Munawar, Khalil Munawar Makhdum, Kitagawa, Junichi, Hossain, Mohammad Zakir

“…Immunoreactivity for TRPV4 was more intense (p < 0.05) in the nerves of symptomatic teeth than those of normal teeth. The number of co-localization spots was increased significantly (p < 0.05) in the dental pulp of symptomatic teeth compared with that of asymptomatic (normal) teeth. …”

VANET–LTE based heterogeneous vehicular clustering for driving assistance and route planning applications by Ahmad, Iftikhar, Noor, Rafidah Md, Ahmedy, Ismail, Shah, Syed Adeel Ali, Yaqoob, Ibrar, Ahmed, Ejaz, Imran, Muhammad

“…These vehicles usually require the use of individual long-term evolution (LTE) connections to send/receive data to/from a remote server to make smart decisions regarding route planning and driving. An increasing number of vehicles on the roads may not only overwhelm LTE network usage but also incur added cost. …”

Generation of an ultrabroadband supercontinuum in the mid-infrared region using dispersion-engineered GeAsSe photonic crystal fiber by Ahmad, Harith, Karim, Mohammad Rezaul, Ghosh, Souvik, Rahman, B.M. Azizur

“…By varying structural parameters pitch (hole to hole spacing) and air-hole diameter to pitch ratio, a number of 10-mm-long hexagonal PCFs made employing GeAsSe ChG glass as a core and air-holes of hexagonal lattice running through their lengths as a cladding are optimized to predict an efficient mid-infrared region SC spectral emission by pumping them using a tunable pump source between 2.9 and 3.3 µm. …”

Use of Nonlinear Features for Automated Characterization of Suspicious Ovarian Tumors Using Ultrasound Images in Fuzzy Forest Framework by Acharya, U. Rajendra, Akter, Ayesha, Chowriappa, Pradeep, Dua, Sumeet, Raghavendra, U., Koh, Joel E. W., Tan, Jen Hong, Leong, Sook Sam, Vijayananthan, Anushya, Hagiwara, Yuki, Ramli, Marlina Tanty, Ng, Kwan Hoong

“…The proposed method is robust and reproducible as it uses maximum number subjects (469) as compared to state-of-the-art techniques. …”

A new approach to evaluate the impact of thermophysical properties of nanofluids on heat transfer and pressure drop by Abdelrazek, Ali H., Alawi, Omer A., Kazi, Salim Newaz, Yusoff, Nukman, Chowdhury, Zaira Zaman, Sarhan, Ahmed Aly Diaa Mohammed

“…The numerical solutions for the average Nusselt number and pressure drop presents a good agreement with the experimental results as the average error was less than 5% for both the cases of heat transfer and pressure loss data. …”

Efficient micropropagation protocol and genome size estimation of an important cover crop, Mucuna bracteata DC. ex Kurz by Abd Aziz, Nazrin, Tan, Boon Chin, Othman, Rofina Yasmin, Khalid, Norzulaani

“…In vitro-derived cotyledonary nodes showed the highest number of shoots per explant (5.60) and rooting response (92.9%) when cultured on Murashige and Skoog medium containing 4.44 µM 6-benzylaminopurine and 10.7 µM 1-naphthaleneacetic acid, respectively. …”