Osteoarthritis genetics: Current status and future prospects af Wilkins, J, Loughlin, J, Snelling, S

“...Epidemiological studies have shown that OA is a complex, multifactorial disorder with a number of risk factors, including environmental and genetic components. ...”

The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni). af Trevett, A, Lalloo, D, Nwokolo, N, Naraqi, S, Kevau, I, Theakston, R, Warrell, D

“...The only significant difference between a small number of patients given 2 vials of antivenom and patients given a single vial at the same time after envenoming was a marginally shorter duration of intubation in those who required it. ...”

Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes. af Brownlees, J, Irving, N, Brion, J, Gibb, B, Wagner, U, Woodgett, J, Miller, C

“...Transgene-derived mRNAs were detected in the brains of a number of the transgenic mouse lines and several of these transgenic lines displayed transgenic GSK-3beta activity. ...”

Boolean tensor decomposition for conjunctive queries with negation af Abo Khamis, M, Ngo, H, Olteanu, D, Suciu, D

“...Its query complexity depends on the structure of the conjunction of negated relations; in general it is exponential in the number of join variables occurring in negated relations yet it becomes polynomial for several classes of queries. ...”

DMS: differentiable mean shift for dataset agnostic task specific clustering using side information af Hobley, M, Prisacariu, V

“...Unlike previous methods, with or without side information, we do not need to know the number of clusters, their centers or any kind of distance metric for similarity. ...”

Retinal ganglion cells labelled from the pulvinar nucleus in macaque monkeys. af Cowey, A, Stoerig, P, Bannister, M

“...Primate gamma cells formed the great majority of classifiable cells and, like the primate alpha cells that were found in much smaller numbers, they were already known to send axons to the superior colliculus and to the pretectal complex. ...”

Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease. af Oliver, P, Bitoun, E, Davies, K

“...One of the most important features of this strategy is the ability to identify and compare a number of mutations in the same gene, an allelic series. ...”

An ethics framework for research into heterogeneous systems af Happa, J, Nurse, J, Goldsmith, M, Creese, S, Williams, R

“...Using our framework, researchers should be able to deliver use-case scenarios that should be peer-reviewed by a large number of experts in dissimilar domains with the aim of identifying issues to why the research and development proposed is not done responsibly, so researchers can address these concerns. ...”

Human connectomics. af Behrens, T, Sporns, O

“...Connectivity analysis has already led to a number of new insights about brain organization. For example, segregated brain regions may be identified by their unique patterns of connectivity, structural and functional connectivity may be compared to elucidate how dynamic interactions arise from the anatomical substrate, and the architecture of large-scale networks connecting sets of brain regions may be analysed in detail. ...”

Raising the achievement of young-beginner readers of French through strategy instruction af Macaro, E, Erler, L

“...This article reports on an intervention study of reading comprehension among young-beginner learners of French as a foreign language (L2) in England. A number of factors are currently contributing to low achievement in reading among this population of learners. ...”

Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. af Evangelou, N, Esiri, M, Smith, S, Palace, J, Matthews, P

“...The calculated total number of axons was reduced significantly (mean +/- SD, 5.4 x 10(7) +/- 3.1 x 10(7)) compared with normal controls (11.6 x 10(7) +/- 2.2 x 10(7), p = 0.001) with a reduction both in axonal density (median, 34%; range, 16-56%; p = 0.004) and area (mean +/- SD: multiple sclerosis, 584 +/- 170 mm2; controls, 871 +/- 163 mm2; p = 0.004). ...”

The McKay correspondence for isolated singularities via Floer theory af McLean, M, Ritter, AF

“...Given an isolated singularity Cn/G for a finite subgroup G ⊂ SL(n, C) and any crepant resolution Y , we prove that the rank of positive symplectic cohomology SH∗ +(Y ) is the number |Conj(G)| of conjugacy classes of G, and that twice the age grading on conjugacy classes is the Z-grading on SH∗−1 + (Y ) by the Conley-Zehnder index. ...”

Direct observation of supported lipid bilayer formation with interferometric scattering microscopy af Andrecka, J, Spillane, K, Arroyo, J, Kukura, P

“...Here, we used interferometric scattering microscopy (iSCAT) to directly visualize membrane formation from nanoscopic vesicles in real time. We observed a number of previously proposed phenomena such as vesicle adsorption, rupture, movement and a wave-like bilayer spreading. ...”

The moral and fiscal implications of antiretroviral therapies for HIV in Africa af Collier, P, Sterck, O

“...However, even with optimal prevention the quasi-liability is likely to remain too high to be affordable for a significant number of African countries. Extending the model to two players, we show that if the international community accepts part of the quasi-liability, as it does, it should finance a broadly equal share of prevention and treatment of future infections to mitigate moral hazard and avoid sub-optimal investment in prevention....”

Airlines' choice of aircraft size : explanations and implications af Givoni, M, Rietveld, P

“...Regression analysis of over 500 routes in the US, Europe and Asia provides empirical evidence that the choice of aircraft size is mainly influenced by route characteristics (e.g. distance, level of demand and level of competition) and almost not at all by airport characteristics (e.g. number of runways and whether the airport is a hub or slot coordinated). ...”

Modelling an isolated dust grain in a plasma using matched asymptotic expansions af Ockendon, J, Arinaminpathy, N, Allen, J

“...We derive analytical expressions for the electric potential, the ion number density and ion velocity. This requires only one computation that is not specific to a single set of dust–plasma parameters, and sheds new light on the shielding distance of a dust grain. ...”

Náttúra by Kitchen Theory: An immersive multisensory dining concept af Youssef, J, Spence, C

“...It was inspired by the New Nordic Cuisine Manifesto which has influenced not only cuisine in the Nordic countries but international gastronomy more broadly for a number of years now. This multisensory dining concept incorporated dishes that have subsequently appeared in peer-reviewed academic research, including in this journal, thus highlighting the potential of practice-led gastrophysics research (as in research that was designed to optimize the eye-appeal of the plating of one of the dishes served on the menu). ...”

Using learning of speed to stabilize scale in monocular localization and mapping af Frost, D, Murray, D, Prisacariu, V

“...We compare the performance with number of other methods for scale-drift correction from monocular data, and show that our solution achieves more accurate results....”

Time from symptom onset to hospitalisation of coronavirus disease 2019 (COVID-19) cases: implications for the proportion of transmissions from infectors with few symptoms af Thompson, RN, Lovell-Read, FA, Obolski, U

“...Here, we show that the proportion of infections arising from hosts with few symptoms at the start of an outbreak can, in combination with the basic reproduction number, indicate whether or not interventions targeting symptomatic hosts are likely to be effective. ...”

Interplay of chiral and helical states in a quantum spin hall insulator lateral junction af Calvo, M, de Juan, F, Ilan, R, Fox, E, Bestwick, A, Mühlbauer, M, Wang, J, Ames, C, Leubner, P, Brüne, C, Zhang, S, Buhmann, H, Molenkamp, L, Goldhaber-Gordon, D

“...We control the carrier density inside and outside a junction region independently and hence tune the number and nature of 1D edge modes propagating in each of those regions. ...”