A Retrospective Study of Ocular Cancer in Saudi Arabia: 25-Year Analysis by Saad AL-Zomia A, AL-Zehefa IA, Alqarni AM, Al Muidh AM, Mesfer Almousa A, Faez Al-Qaed A, Alshahrani AS, Mohammed Asiri B, Asiri GB, Ali Lahiq L, Al-Amri MA, Al-Nujimi MS, Alfaisal SM, Tawhari I

“…The data also revealed differences in the number of reported cases over time, as well as in the representation of eye cancer cases by gender and nationality. While many ocular cancer pathologies were seen, with “Retinoblastoma, not otherwise specified” being the most common (53.32%), the incidence rates for males and females remained largely stable over time.Conclusion: The study emphasizes the need for continued monitoring, research, and analysis of potential of epidemiology of ocular cancer occurrence in Saudi Arabia. …”
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Revolutionizing ocular cancer management: a narrative review on exploring the potential role of ChatGPT by Saud S. Alotaibi, Amna Rehman, Muhammad Hasnain

“…This paper pioneers the exploration of ocular cancer, and its management with the help of Artificial Intelligence (AI) technology. …”
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A joinpoint and age–period–cohort analysis of ocular cancer secular trends in Iran from 2004 to 2016 by Mohammad Abolhosseini, Zahra Khorrami, Sare Safi, Mohammad Esmaeil Akbari, Seyed Mohamadmehdi Moshtaghion, Seyed Farzad Mohammadi, Mozhgan Rezaei Kanavi, Saeed Karimi

“…Abstract Investigating secular trends of ocular cancer registration in Iran. After acquiring Iranian national population-based cancer registry data, trends of age-standardised incidence rates (ASIR) of ocular cancers and annual percent changes (APC) between 2004 and 2016 were analysed in age groups, gender, topography and morphology types with joinpoint regression analysis. …”
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Histopathological profile of orbito-ocular cancers at a tertiary hospital in Northern Malawi: a retrospective cross-sectional study by Tsung-Shu Joseph Wu, Chikondi Sharon Chimbatata, Frank Watson Sinyiza, Balwani Chingatichifwe Mbakaya, Paul Uchizi Kaseka, Pocha Kamudumuli, Master R O Chisale, Alfred B Kayira

“…Objective Orbito-ocular cancers are a common cause of morbidity and mortality in our population, yet these cancers have not been adequately described in Malawi. …”
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Publisher Correction: A joinpoint and age–period–cohort analysis of ocular cancer secular trends in Iran from 2004 to 2016 by Mohammad Abolhosseini, Zahra Khorrami, Sare Safi, Mohammad Esmaeil Akbari, Seyed Mohamadmehdi Moshtaghion, Seyed Farzad Mohammadi, Mozhgan Rezaei Kanavi, Saeed Karimi

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Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders by Binapani Mahaling, Shermaine W. Y. Low, Molly Beck, Devesh Kumar, Simrah Ahmed, Thomas B. Connor, Baseer Ahmad, Shyam S. Chaurasia

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Investigating Vitreous Cytokines in Choroidal Melanoma by Hakan Demirci, Lu Tang, F. Yesim Demirci, Cem Ozgonul, Sarah Weber, Jeffrey Sundstrom

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Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma by Chen-Ching Peng, Shreya Sirivolu, Sarah Pike, Mary E. Kim, Bibiana Reiser, Hong-Tao Li, Gangning Liang, Liya Xu, Jesse L. Berry

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Nanotechnology-based strategies overcoming the challenges of retinoblastoma: a comprehensive overview and future perspectives by Shymaa Hatem, Donia Mohammed, Nermeen Ezzat

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Impact of Different Mucoadhesive Polymeric Nanoparticles Loaded in Thermosensitive Hydrogels on Transcorneal Administration of 5-Fluorouracil by Angela Fabiano, Anna Maria Piras, Lorenzo Guazzelli, Barbara Storti, Ranieri Bizzarri, Ylenia Zambito

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Advantages and Disadvantages of Using Magnetic Nanoparticles for the Treatment of Complicated Ocular Disorders by Elena K. Schneider-Futschik, Felisa Reyes-Ortega

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Establishment of patient-derived xenografts of retinoblastoma and choroidal melanoma on the avian chorioallantoic membrane by Nimita Kant, Perumal Jayaraj, Seema Sen, Harshita Rupani, Pranavi Kumar, Shefali Dahiya, Palak Chugh, Muskaan Gupta, Manisha Sengar

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Genetic Risk Factors and Clinical Outcomes in Childhood Eye Cancers: A Review by Syed Hameed, Angeli Christy Yu, Bashaer Almadani, Shereen Abualkhair, Khabir Ahmad, Giorgio Zauli

“…Furthermore, it also explores the outcomes and implications of these genetic discoveries in treating pediatric ocular cancer. These findings underscore the significance of genetic research in guiding early interventions and improving outcomes in children with ocular cancers.…”
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Genome-wide aberrant methylation in primary metastatic UM and their matched metastases by Kyra N. Smit, Ruben Boers, Jolanda Vaarwater, Joachim Boers, Tom Brands, Hanneke Mensink, Robert M. Verdijk, Wilfred F. J. van IJcken, Joost Gribnau, Annelies de Klein, Emine Kilic

“…Abstract Uveal melanoma (UM) is an aggressive intra-ocular cancer with a strong tendency to metastasize. …”
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RB1 gene mutations in Argentine retinoblastoma patients. Implications for genetic counseling. by Diana Parma, Marcela Ferrer, Leonela Luce, Florencia Giliberto, Irene Szijan

“…Retinoblastoma (RB) is an inherited childhood ocular cancer caused by mutations in the tumor suppressor RB1 gene. …”
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Early treatment and toxicity outcomes for small posterior uveal melanomas treated using custom loaded eye plaques by Sara Medek, Zelia M. Correa, Brad Huth, Vinita Takiar

“…IntroductionIodine-125 loaded Collaborative Ocular Melanoma Study plaques can achieve excellent tumor control for patients diagnosed with uveal melanomas. Our ocular cancer team hypothesized that use of novel, partially loaded COMS plaques could ease and improve accurate plaque placement during treatment of small, posterior tumors while providing equivalent tumor control.Materials/methodsRecords of 25 patients treated with custom plaques were compared to 20 patients treated with fully loaded plaques, who had received treatment prior to our institution’s adopting the use of these partial plaques. …”
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Absent MicroRNAs in Different Tissues of Patients with Acquired Cardiomyopathy by Christine S. Siegismund, Maria Rohde, Uwe Kühl, Felicitas Escher, Heinz Peter Schultheiss, Dirk Lassner

“…For the first time, non-detectable miRNAs in different tissues and body fluids from patients with different diseases (cardiomyopathies, Alzheimer’s disease, bladder cancer, and ocular cancer) were analyzed and compared in this study. miRNA expression data were generated by microarray or TaqMan PCR-based platforms. …”
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Validation of an Ultraviolet Light Response Gene Signature for Predicting Prognosis in Patients with Uveal Melanoma by Carlos A. Orozco, Alejandro Mejía-García, Marcela Ramírez, Johanna González, Luis Castro-Vega, Richard B. Kreider, Silvia Serrano, Alba Lucia Combita, Diego A. Bonilla

“…Uveal melanoma (UVM) is a highly aggressive ocular cancer with limited therapeutic options and poor prognosis particularly for patients with liver metastasis. …”
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Uveal Melanoma: A European Network to Face the Many Challenges of a Rare Cancer by Sophie Piperno-Neumann, Jose Maria Piulats, Matthias Goebeler, Iain Galloway, Iwona Lugowska, Jürgen C. Becker, Pia Vihinen, Joachim Van Calster, Theodora Hadjistilianou, Rui Proença, Jose Maria Caminal, Muriel Rogasik, Jean-Yves Blay, Ellen Kapiteijn

“…Uveal melanoma (UM) is the most frequent primary ocular cancer in adults, accounting for 5% of all melanomas. …”
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Quality of life among people with eye cancer: a systematic review from 2012 to 2022 by Yonghui Huang, Yunfei Guo

“…Conclusion This systematic review identified the QOL levels and several factors that influence the QOL of ocular cancer patients worldwide, due to the variability in quality of the studies, it also showed the need for further research to assess factors affecting long-term QOL outcomes in RB and UM survivors. …”
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