Characterizing the Impact of Oligomerization on Redox Flow Cell Performance by Weiss, Trent A, Fan, Gang, Neyhouse, Bertrand J, Moore, Evan B, Furst, Ariel, Brushett, Fikile R

“…Post‐mortem analyses reveal that oligomerization does not meaningfully alter decay processes as evinced by similar capacity fade across all species. …”
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Investigation on the mechanism of amyloid beta peptides oligomerization and the process for its inhibition by Zhao, Li Na

“…Hence, it is the goal of my research to use computational methodologies to reveal the mechanisms of Abeta aggregation in aqueous and membrane environment and the influence of small molecules like curcumin and heme, and the inflammatory proteins like S100A9, on Abeta oligomerization. We have chosen the full-length Abeta peptides as well as the most representative short segments of Abeta and employed the classical molecular dynamics and the sampling-enhanced replica exchange molecular dynamics simulations, to investigate the aggregation and atomic detailed interaction among Abeta, lipids, small molecules and macromolecules.…”
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Inhibitory Potential of the Truncated Isoforms on Glutamate Transporter Oligomerization Identified by Computational Analysis of Gene-Centric Isoform Maps by Karagöl, Alper, Karagöl, Taner, Li, Mengke, Zhang, Shuguang

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Membrane cholesterol modulates oligomeric status and peptide-membrane interaction of severe acute respiratory syndrome coronavirus fusion peptide by Meher, Geetanjali, Bhattacharjya, Surajit, Chakraborty, Hirak

“…Our results clearly demonstrate that the membrane cholesterol alters the oligomeric status of the membrane-bound peptide and the effect of peptide binding on the depth-dependent membrane organization and dynamics. …”
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Cooperativity and induced oligomerization control the interaction of SARS-CoV-2 with its cellular receptor and patient-derived antibodies by Asor, R, Olerinyova, A, Burnap, SA, Kushwah, MS, Hensen, M, Vasiljevic, S, Chang, L, Dejnirattisa, W, Supasa, P, Stuart, DI, Screaton, GR, Zitzmann, N, Benesch, JLP, Struwe, WB, Kukura, P

Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface by Söderberg, Christopher A. G., Månsson, Cecilia, Bernfur, Katja, Rutsdottir, Gudrun, Härmark, Johan, Rajan, Sreekanth, Al-Karadaghi, Salam, Rasmussen, Morten, Höjrup, Peter, Hebert, Hans, Emanuelsson, Cecilia

“…The remarkably efficient suppression of amyloid fibril formation by the DNAJB6 chaperone is dependent on a set of conserved S/T-residues and an oligomeric structure, features unusual among DNAJ chaperones. …”
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Ultrafast time-resolved fluorescence study on formation and excitation dynamics of human telomeric and homo-oligomeric i-motifs at neutral pH by Ma, Chensheng, Chan, Ruth Chau-Ting, Kwok, Wai-Ming

“…Asides from the common double stranded structure, nucleic acids depending on the base content and environmental condition may take many non-canonical secondary structures, including the fourstranded intercalated i-motif structure formed from cytosine-rich sequences that are abundant throughout the human genome.[1,2] The structures of i-motifs are known to be stable at slightly acidic condition, whether they can also be formed at the physiologically relevant neutral pH condition remains elusive and currently one of the frontier issues in the study of non-canonical nucleic acid structures.[3,4] Herein we present a comparative steady-state and ultrafast time-resolved fluorescence investigation of a homo-oligomeric and human telomeric cytosine-rich sequence at both the acidic and neutral pH.…”
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A feasibility study on computational prediction on the death domain superfamily protein oligomers by Zhang, Jiawen

“…This computational work provides a framework to improve our understanding of death domain assembling oligomeric signalling complexes to direct innate immune and inflammatory responses.In order to investigate the signaling transduction process and validate our prediction and hypothesis, we conducted the structural study of the CARD8-CARD oligomeric complex by cryoEM. …”
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Structural study of plant cellulose synthase and atypical profilin3 by Qiao, Zhu

“…A low-resolution model of oligomeric full-length cellulose synthase was also obtained by Cryo-EM. …”
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Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications by Ayoub, N, Djabeur, N, Harder, D, Jeckelmann, J, Ucurum, Z, Hirschi, S, Fotiadis, D

“…Cryo-electron microscopy and 2D classification of protein particles provided a projection structure identifying the oligomeric state of RlActR as a pentamer. Efficient establishment of a proton gradient across lipid membranes upon light illumination was demonstrated using RlActR-overexpressing E. coli cells and reconstituted RlActR proteoliposomes. …”

Phase separation of a microtubule plus-end tracking protein into a fluid fractal network by Czub, MP, Uliana, F, Grubić, T, Padeste, C, Rosowski, KA, Lorenz, C, Dufresne, ER, Menzel, A, Vakonakis, I, Gasser, U, Steinmetz, MO

“…Together, our findings offer insights into the structure, dynamic rearrangement, and organization of a complex, oligomeric, and multidomain protein in both dilute and condensed states. …”

The mammalian EMC in membrane protein biogenesis by Volkmar, N

“…<p>The mammalian Endoplasmic Reticulum Membrane protein Complex (mEMC) has previously been implicated in a range of cellular activities, including the biogenesis of oligomeric plasma membrane receptors, endoplasmic reticulum (ER)-mitochondrial phospholipid transfer, and as a host factor modulating viral pathogenicity. …”

Characterization of mechanical properties of polyurea by You, Mei Yu

“…The polyurea was successfully synthesized with Isonate-143LP Modified MDI and oligomeric diamine (VERSALINK P1000). The polyureas were allowed to cure until different factors and conditions for up to 5 days. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes by Low, Jianrong L., Gehring, Adam J., Kranz, David M., Grotenbreg, Gijsbert M., Yau, Yin Hoe, Shochat, Susana Geifman, Bertoletti, Antonio, Naidoo, Anneta, Yeo, Gladys, Ho, Zi Zong

“…Collectively, the results highlight the promiscuity of our soluble TCR, which could be an advantageous feature when targeting cells infected with a mutation-prone virus, but that binding of the soluble oligomeric TCR relies considerably on the surface density of the presented antigen.…”
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Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis by Singal, Bharti

“…The MtRel ACT structure was determined as a dimer and the oligomeric state was further confirmed using SAXS. The crucial dimeric interface residues were identified, and the mutants were studied to understand the role of these residues in dimerization. …”
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Biophysical properties and supramolecular structure of self-assembled liposome/ε-peptide/DNA nanoparticles : correlation with gene delivery by Yan, Jiang, Korolev, Nikolay, Eom, Khee Dong, Nordenskiöld, Lars, Tam, James P.

“…Using solid-phase synthesis, lysine can be oligomerized by a reaction of the peptide carboxylate with the ε-amino group to produce nontoxic, biodegradable cationic peptides, ε-oligo(l-lysines). …”
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Synthesis of heavy cyanide analogs for the design of novel Prussian blue analogs by Yang, E

“…The factors that favor oligomerization are elucidated, providing a framework for understanding the stabilization of metal cyaphide complexes.…”

Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors by Shapiguzov, Alexey, Fernie, Alisdair R., Vainonen, Julia P., Hunter, Kerri, Tossavainen, Helena, Tiwari, Arjun, Järvi, Sari, Hellman, Maarit, Aarabi, Fayezeh, Alseekh, Saleh, Wybouw, Brecht, Van Der Kelen, Katrien, Nikkanen, Lauri, Krasensky-Wrzaczek, Julia, Sipari, Nina, Keinänen, Markku, Tyystjärvi, Esa, Rintamäki, Eevi, De Rybel, Bert, Salojärvi, Jarkko, Van Breusegem, Frank, Brosché, Mikael, Permi, Perttu, Aro, Eva-Mari, Wrzaczek, Michael, Kangasjärvi, Jaakko

“…ROS alter the abundance, thiol redox state and oligomerization of the RCD1 protein in vivo, providing feedback control on its function. …”
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Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications by Zhang, Simin

“…Using chemical crosslinking and immunofluorescence staining, in Paper II we could show that the S protein MPER could oligomerize and further heteromerize with the N-terminal internal fusion peptide (IFP). …”
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Biomolecular engineering of a human beta defensin model for increased salt resistance by Li, Xiang, Saravanan, Rathi, Kwak, Sang Kyu, Leong, Susanna Su Jan

“…The mutant hBD28 did not exhibit obvious differences with respect to hydrophobicity, oligomerization ability, and secondary structure compared to the wild type peptide. …”
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