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261
Genome wide profiling of tongue and cheek cancer using high resolution array based CGH
Published 2011“…For cheek cancer, the cancer associated significant pathway was apoptosis and survival (the role of CDK5 in neuronal death and survival). An oncogene located at 8p12 was identified in this pathway is NRG1. …”
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262
Prevalence and molecular variance of human papillomavirus among women in Kota Kinabalu, Sabah, Malaysia
Published 2019“…Toe analyses of sequence variation and construction of phylogenetic trees indicated that at least four highly oncogenic lineages were found among high-risk HPV variants identified in the study namely HPV-16 A4 (Asian), HPV-33 Al, HPV-56 B, and HPV-58 A, respectively. …”
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263
Prevalence and molecular variance of human papillomavirus among women in Kota Kinabalu, Sabah, Malaysia
Published 2019“…Toe analyses of sequence variation and construction of phylogenetic trees indicated that at least four highly oncogenic lineages were found among high-risk HPV variants identified in the study namely HPV-16 A4 (Asian), HPV-33 Al, HPV-56 B, and HPV-58 A, respectively. …”
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264
In vitro and in vivo anti-lung cancer properties of leaf ethanolic extract of morinda citrifolia l.
Published 2015“…The MLE inhibited the tumour growth cellular genes (transformed mouse 3T3 cell double minute 2 (MDM2), V-raf-leukemia viral oncogene 1 (RAF1), and mechanistic target of rapamycin (MTOR)) mRNA expressions. …”
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265
Machine learning methods for predicting cancer drug effects from signaling and cell fate data
Published 2017“…Hence comparative analysis of normal and oncogenic signal transduction pathways may provide insights into dynamics of cancer drug induced signaling changes and enable the discovery of novel and effective anti-cancer therapies. …”
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266
Identification of differentially regulated genes in breast (MCF-7) and lung (H1299) cancer cell lines during Newcastle disease virus strain AF2240 infection
Published 2012“…Newcastle disease virus (NDV), a member of Paramyxoviridae family is known for its selective oncogenic effects in cancer cells. Even though NDV infections in cancer cells were shown to result in cell death through apoptosis, the actual mechanism of NDV-induced cell death process has not been thoroughly investigated. …”
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267
In silico-guided sequence modifications of K-ras epitopes improve immunological outcome against G12V and G13D mutant KRAS antigens
Published 2018“…Background: Somatic point substitution mutations in the KRAS proto-oncogene primarily affect codons 12/13 where glycine is converted into other amino acids, and are highly prevalent in pancreatic, colorectal, and non-small cell lung cancers. …”
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268
An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study
Published 2024“…Two proteins, lactadherin and proto-oncogene tyrosine-protein kinase receptor, were most consistently selected and slightly improved model performance. …”
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269
[Withdrawn] Regulation of insulin resistance by myostatin
Published 2013“…Additionally, elevated Mstn levels were found to activate the IRS1 specific E3 ligase, Cblb (Casitas B-lineage lymphoma proto-oncogene b) which degraded IRS1 protein to induce insulin resistance. …”
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270
Determination of phosphatidylinositol-3-kinase gene copy number and protein expression in nasopharyngeal carcinoma by real-time PCR and immunohistochemistry
Published 2013“…The pathway, with PTEN gene (tumor suppressor) and PIK3CA oncogene, is implicated in the insensitivity of cancer tumors to IGF1 and insulin AKT is recruited to the cell membrane using the PH domain ahead PI3K activation, and phosphatidyl-3,4,5-triphosphate (PIP3) is created. …”
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271
Functional analysis of microrna-181A : identification of target proteins and application in HCC therapy
Published 2014“…Overall, miR-181a appears to activate mainly cancer-promoting pathways, and may act as an oncogene in HepG2 cells. Inhibiting it, on the other hand, activates mainly the tumour-suppressing pathways, making it a possible option for therapy. …”
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272
Antitumor Effect of Zerumbone Isolated from Lempoyang (Zingiber Zerumbet) on Human Cervical Cancer Cells and Mouse Cervical Intraepithelial Neoplasia
Published 2009“…It has been found that ZER also modulated the ratio of Bcl-2 and Bax, which further supported the intonated levels of LCMM extracted and RT-PCR amplified mRNA of such proteins as well as c-myc oncogene, which was detected only in the CIN cancer group. …”
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273
STATUS METILASI GEN BRCA1 GEN BRCA2 EKSPRESI PROTEIN BRCA1 PROTEIN BRCA2 HUBUNGANNYA DENGAN TERJADINYA TUMOR EPITELIAL OVARIUM DERAJAD DIFERENSIASI JENIS HISTOPATOLOGI STADIUM DAN...
Published 2013“…Cancer develops through multistep process in which the genomes of cancer cells mutate in several groups of genes such as proto-oncogen, tumor suppresor genes and other genes which directly or indirectly control the cell proliferation. …”
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274
Quantification of Circulating Epstein-Barr Virus Latent Membrane Protein 1 Gene and Analysis Of 30-Bp Deletion and Xhoi-Loss Variants in Nasopharyngeal Carcinoma
Published 2007“…The presence of EBV LMP1 gene variants were shown to be more oncogenic than the LMP1 gene from the prototype virus, B95-8. …”
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275
Expression and association of miR-181a and miR-663 and their target genes in head and neck cancer
Published 2018“…Taken together, these results suggest that hsa-miR-181a-2-3p and hsa-miR- 663 may serve as an oncogene in head and neck cancer. Furthermore, hsamiR- 181a-2-3p and hsa-miR-663 might be used as new biomarkers together with their common predicted targets in the prediction of prognosis of HNC in clinical practice. …”
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Thesis