Oncogenic activation of the stat3 pathway drives pd-l1 expression in natural killer/t-cell lymphoma by Song, Tammy Linlin, Nairismägi, Maarja-Liisa, Laurensia, Yurike, Lim, Jing-Quan, Tan, Jing, Li, Zhi-Mei, Pang, Wan-Lu, Kizhakeyil, Atish, Wijaya, Giovani-Claresta, Huang, Da-Chuan, Nagarajan, Sanjanaa, Chia, Burton Kuan-Hui, Cheah, Daryl, Liu, Yan-Hui, Zhang, Fen, Rao, Hui-Lan, Tang, Tiffany, Wong, Esther Kam-Yin, Bei, Jin-Xin, Iqbal, Jabed, Grigoropoulos, Nicholas-Francis, Ng, Siok-Bian, Chng, Wee-Joo, Teh, Bin-Tean, Tan, Soo-Yong, Verma, Navin Kumar, Fan, Hao, Lim, Soon-Thye, Ong, Choon-Kiat

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Transcriptomic analysis of KSHV-infected primary oral fibroblasts: the role of interferon-induced genes in the latency of oncogenic virus by Dai, Lu, Bai, Lihua, Lin, Zhen, Qiao, Jing, Yang, Liang, Flemington, Erik K., Zabaleta, Jovanny, Qin, Zhiqiang

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Pharmacological modulation of oncogenic Ras by natural products and their derivatives: renewed hope in the discovery of novel anti-Ras drugs by Quah, Shun Ying, Tan, Michelle Siying, Teh, Yuan Han, Stanslas, Johnson

“…Oncogenic rat sarcoma (Ras) is linked to the most fatal cancers such as those of the pancreas, colon, and lung. …”
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Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein by Tan, Michelle Siying

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Investigating super-enhancer-associated chromatin interactions at the HOXA9-MEIS1 oncogene signalling axis in myeloid leukaemia by Wang, Benny Zheng Jie

“…HOXA9 and MEIS1 are two commonly overexpressed oncogenes that are associated with poor prognoses in myeloid leukaemia patients. …”
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Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma by Ang, Daniel Aron, Carter, Jean-Michel, Deka, Kamalakshi, Tan, Joel H. L., Zhou, Jianbiao, Chen, Qingfeng, Chng, Wee Joo, Harmston, Nathan, Li, Yinghui

“…In multiple myeloma, abnormal plasma cells establish oncogenic niches within the bone marrow by engaging the NF-κB pathway to nurture their survival while they accumulate pro-proliferative mutations. …”
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Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets by Kuznetsov, Vladimir A., Tang, Zhiqun, Ivshina, Anna V.

“…The miRNAs of these classifiers could control nine oncogenic and two developmental pathways, highlighting common underlying pathologic mechanisms and perspective targets for the further development of a personalized prognosis assay(s) and the development of miRNA-interconnected pathway-centric and multi-agent therapeutic intervention.…”
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Validation of a multiplex RT-PCR assay for screening significant oncogene fusion transcripts in children with acute lymphoblastic leukaemia by Ariffin, H., Chen, S.P., Wong, H-L, Yeoh, A.

Oncogenic human papillomavirus genital infection in southern Iranian women: population-based study versus clinic-based data by Eghbali, S.S., Amirinejad, R., Obeidi, N., Mosadeghzadeh, S., Vahdat, K., Azizi, F., Pazoki, R., Sanjdideh, Z., Amiri, Z., Nabipour, I., Zandi, K.

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Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma by Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Tan, Tuan Zea, Toh, Sabrina Hui-Min, Tang, Nicole Xin Ning, Jia, Yunlu, See, Yi Xiang, Fullwood, Melissa Jane, Sanda, Takaomi, Chng, Wee-Joo

“…We show that myeloma cells frequently acquire SE that transcriptionally activate an oncogene PPP1R15B, which encodes a regulatory subunit of the holophosphatase complex that dephosphorylates translation initiation factor eIF2α. …”
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Regulation of chromatin interactions to the MYC oncogene by long non-coding RNA PVT1 in acute myeloid leukemia cell lines by Nur Zahwah Asa'ad Sameer Bagharib

“…Our study aims to investigate the regulation of lncRNA PVT1 in activating the MYC oncogene via chromatin interactions in Acute Myeloid Leukemia (AML) cell lines. …”
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Overexpression of miR‑361‑5p plays an oncogenic role in human lung adenocarcinoma through the regulation of SMAD2 by Othman, Norahayu, Nagoor, Noor Hasima

Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model by Kehinde, Samuel Abiodun, Olajide, Abosede Temitope, Fatokun, Tolulope Peter, Faroud, Dalia, Hadi, Najah R., Elgazzar, Ahmed M., James, Adewale Segun, Ashour, Mohamed H. Mazhar

“…Overall, the findings indicate that DiNP-induced asthma impairs cardiac functions by induction of key cardiac oncogenes, downregulation of cardiac energy, transduction of enzymes, and promotion of oxidative stress and cellular death. …”
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Expression of proliferating cell nuclear antigen, vimentin and fibroblast growth factor receptors in canine mammary gland tumours as potential markers for tumour growth agressivene... by Sahabi, Kabiru

Subjects: “…Oncogenic viruses…”
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Super-enhancer-driven long non-coding RNA LINC01503, regulated by TP63, is over-expressed and oncogenic in squamous cell carcinoma by Xie, Jian-Jun, Jiang, Yan-Yi, Jiang, Yuan, Li, Chun-Quan, Lim, Mei-Chee, An, Omer, Mayakonda, Anand, Ding, Ling-Wen, Long, Lin, Sun, Chun, Lin, Le-Hang, Chen, Li, Wu, Jian-Yi, Wu, Zhi-Yong, Cao, Qi, Fang, Wang-Kai, Yang, Wei, Soukiasian, Harmik, Meltzer, Stephen J., Yang, Henry, Fullwood, Melissa, Xu, Li-Yan, Li, En-Min, Lin, De-Chen, Koeffler, H. Phillip

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Stromal fibroblasts impaired in TGF-beta signaling prime the microenvironment with extracellular hydrogen peroxide and mitogenic factors to support the oncogenic transformation of adjacent epithelia by Tan, Ming Jie

“…However, the effects of TAK1 and Smad signaling in stromal fibroblasts on the oncogenic potential of adjacent epithelia remain unclear. …”
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Effects of Velogenic Newcastle Disease Virus Strain AFF2240 on the Oncogenes and Marphological Changes of 4T1 Breast Cancer Cell in Balb/c Mice by Eshak, Zolkapli

“…Further analysis of the c-myc, c-erbB2 and c-fos oncogenes revealed that the presences of the oncogenes in all tumor bearing mice group regardless of treatment given. …”
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Analysis of V-Ki-Ras2 Kirsten rat sarcoma viral oncogene (Kras) and differential expressed miRNA in various stages of colorectal cancer by Lye, Kwan Liang

“…Mutations in the V-Ki-Ras2 (Kras) oncogene have been implicated in 30-50% of the colorectal cancer patients and usually lead to significantly poorer prognosis. …”
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Rattle-type Au@Cu 2−x S hollow mesoporous nanocrystals with enhanced photothermal efficiency for intracellular oncogenic microRNA detection and chemo-photothermal therapy by Cao, Yu, Li, Shuzhou, Chen, Chao, Wang, Dongdong, Wu, Tingting, Dong, Haifeng, Zhang, Xueji

“…By conjugating microRNA (miRNA) gene probe on the surface, it can realize the intracellular oncogenic miRNA detection. After loading of anticancer drug doxorubicin into the cavity of the Au@Cu2 xS, the antitumor therapy efficacy is greatly enhanced in vitro and in vivo due to the NIR photoactivation chemo- and photothermal synergistic therapy. …”
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The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor by Hew, Kelly, Dahlroth, Sue-Li, Venkatachalam, Rajakannan, Nasertorabi, Fariborz, Lim, Bee Ting, Cornvik, Tobias Carl, Nordlund, Pär

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