Laser nanostructured gold biosensor for proto-oncogene detection by Cian Hughes, Sithara Sreenilayam, Dermot Brabazon

“…This work offers a scalable, and green approach to fabricating viable biosensors capable of detecting clinically relevant oncogenic targets.…”
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Regulators of Oncogenic Mutant TP53 Gain of Function by Satomi Yamamoto, Tomoo Iwakuma

“…Mutations in TP53 not only disrupt its tumor suppressor function, but also endow oncogenic gain-of-function (GOF) activities in a manner independent of wild-type TP53 (wtp53). …”
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Oncogenic MicroRNAs: Key Players in Malignant Transformation by Tania Frixa, Sara Donzelli, Giovanni Blandino

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Clinical associations and genetic interactions of oncogenic BRAF alleles by Sebastian A. Wagner

“…The presented analyses explore the properties of oncogenic BRAF mutations and will help to further delineate the complex role of BRAF in cancer.…”
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circ_0005962 functions as an oncogene to aggravate NSCLC progression by Zhang Zhihong, Shan Zhenxiu, Chen Rubin, Peng Xiaorong, Xu Bin, Xiao Liang, Zhang Guofei

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Editorial: Oncogenic RAS-Dependent Reprogramming of Cellular Plasticity by Georgia Konstantinidou, Alessandro Rimessi

Subjects: “…oncogenic Ras…”
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Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma by Elena Parmigiani, Verdon Taylor, Claudio Giachino

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Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1 by Archis Bagati, Anna Bianchi-Smiraglia, Sudha Moparthy, Kateryna Kolesnikova, Emily E. Fink, Brittany C. Lipchick, Masha Kolesnikova, Peter Jowdy, Anthony Polechetti, Amin Mahpour, Jason Ross, Joseph A. Wawrzyniak, Dong Hyun Yun, Gyorgy Paragh, Nadezhda I. Kozlova, Albert E. Berman, Jianmin Wang, Song Liu, Michael J. Nemeth, Mikhail A. Nikiforov

“…We find that levels of the FOXQ1 transcription factor, an oncogene in carcinomas, are decreased during melanoma progression. …”
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The Role of Wild-Type RAS in Oncogenic RAS Transformation by Erin Sheffels, Robert L. Kortum

“…The <i>RAS</i> family of oncogenes (<i>HRAS</i>, <i>NRAS</i>, and <i>KRAS</i>) are among the most frequently mutated protein families in cancers. …”
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Characterization of the p53 response to oncogene-induced senescence. by Lidia Ruiz, Magali Traskine, Irene Ferrer, Estrella Castro, Juan F M Leal, Marcelline Kaufman, Amancio Carnero

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Hedgehog signaling and the glioma-associated oncogene in cancer radioresistance by Li Zhang, Yuhan Zhang, Kaixuan Li, Shuai Xue

“…GLI is reported to activate the main DNA repair pathways, to interact with cell cycle regulators like Cyclin D and Cyclin E, to inhibit apoptosis via the activation of B-cell lymphoma-2, Forkhead Box M1, and the MYC proto-oncogene, to upregulate cell stemness related genes (Nanog, POU class 5 homeobox 1, SRY-box transcription factor 2, and the BMI1 proto-oncogene), and to promote cancer stem cell transformation. …”
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PH domain-mediated autoinhibition and oncogenic activation of Akt by Hwan Bae, Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta Salguero, Michael J Eck, Haribabu Arthanari, Philip A Cole

“…Our studies also shed light on the molecular basis for E17K Akt activation as an oncogenic driver.…”
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Exploring the oncogenic roles of LINC00857 in pan-cancer by Xiaomin Ren, Jing Liu, Rui Wang, Xinling Liu, Xiaolin Ma, Zhong Lu, Zhenbo Hu, Mingzhu Zheng, Jingang Ma, Jiaqiu Li

“…Although aberrant LINC00857 expression may play a key role in oncogenesis, no research has analyzed the pan-cancer oncogenic roles of LINC00857, particularly in tumor immunology. …”
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Inflammasome, the Constitutive Heterochromatin Machinery, and Replication of an Oncogenic Herpesvirus by Sumita Bhaduri-McIntosh, Michael T. McIntosh

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Oncogenic structural aberration landscape in gastric cancer genomes by Mihoko Saito-Adachi, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Hirofumi Rokutan, Shinichi Yachida, Mamoru Kato, Akihiko Fukagawa, Tatsuhiro Shibata

“…Here, we examine 170 GC whole genomes to unravel the oncogenic structural aberration landscape in GC genomes and identify six rearrangement signatures (RSs). …”
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The discovery of AVIL as a bona fide oncogene in glioblastoma by Zhongqiu Xie, Hui Li

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Targeting the oncogenic activity of TCF3-HLF in leukemia by Yun Huang, Jean-Pierre Bourquin

“…The oncogenic fusion transcription factor TCF3-HLF identifies an aggressive subtype of acute lymphoblastic leukemia. …”
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The Influence of Oncogenic Viruses in Renal Carcinogenesis: Pros and Cons by Bianca Manole, Costin Damian, Simona-Eliza Giusca, Irina Draga Caruntu, Elena Porumb-Andrese, Catalina Lunca, Olivia Simona Dorneanu, Luminita Smaranda Iancu, Ramona Gabriela Ursu

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Tumor Suppressors Having Oncogenic Functions: The Double Agents by Neerajana Datta, Shrabastee Chakraborty, Malini Basu, Mrinal K. Ghosh

“…Cancer progression involves multiple genetic and epigenetic events, which involve gain-of-functions of oncogenes and loss-of-functions of tumor suppressor genes. …”
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Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma by Oscar Urtatiz, Amanda Haage, Guy Tanentzapf, Catherine D Van Raamsdonk

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