Disentangling oncogenic amplicons in esophageal adenocarcinoma by Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier Ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

“…Esophageal adenocarcinoma is a prominent example of cancer characterized by frequent amplifications in oncogenes. However, the mechanisms leading to amplicons that involve breakage-fusion-bridge cycles and extrachromosomal DNA are poorly understood. …”
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Discovery and characterization of JMJD6 as a novel oncogene. by Lee, Yi Fang.

“…Several oncogene candidates were identified for siRNA-mediated functional screening. …”
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Precision oncology : oncogenic stat3 signalling in brain tumours by Tan, Melanie Si Yan

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Paracrine effect of TAK1 in fibroblasts on the oncogenic potential of adjacent epithelia. by Yeo, Ronne Wee Yeh.

“…Expression profiling of the epidermis revealed a pattern of gene expression which reflects an oncogenic potential. Levels of various growth-promoting factors in the conditioned media were also elevated. …”
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Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer by Kamaruzman, Nur Izyani, Aziz, Noraini Abd, Poh, Chit Laa, Chowdhury, Ezharul Hoque

“…Overexpression of oncogenes and cross-talks of the oncoproteins-regulated signaling cascades with other intracellular pathways in breast cancer could lead to massive abnormal signaling with the consequence of tumorigenesis. …”

Circulating microRNAs in oncogenic viral infections: potential diagnostic biomarkers by Kinza Hasham, Naveed Ahmed, Basit Zeshan

“…Even though many viruses can cause different tumors in animals, only some of them are linked with human cancers and are presently regarded as oncogenic viruses. These viruses include Human Papillomavirus (HPV), Hepatitis B (HBV) and Hepatitis C Virus (HCV), Epstein Barr Virus (EBV), Human Herpes Virus 8 (HHV8), Human T cell Leukemia Virus (HTLV) and Merkel Cell Polyomavirus (MCPyV). …”
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A preliminary study of p53 oncogene expression in lung samples by Rahman, Md.Tahminur

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Globally invariant behavior of oncogenes and random genes at population but not at single cell level by Sirbu, Olga, Helmy, Mohamed, Giuliani, Alessandro, Selvarajoo, Kumar

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Identification of novel oncogenes with prognostic relevance and elucidation of their functional role in gastric cancer by Ang, Grace Swee Ha

“…Identification of novel oncogenes with prognostic relevance and elucidation of their functional role in gastric cancer. …”
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Common oncogenic mutations are infrequent in oral squamous cell carcinoma of asian origin by Zanaruddin, S.N., Yee, P.S., Hor, S.Y., Kong, Y.H., Ghani, W.M., Mustafa, W.M., Zain, R.B., Prime, S.S., Rahman, Z.A., Cheong, S.C.

“…OBJECTIVES: The frequency of common oncogenic mutations and TP53 was determined in Asian oral squamous cell carcinoma (OSCC). …”
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Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function by Hocker, Harrison J., Cho, Kwang Jin, Chen, Chung Ying K., Rambahal, Nandini, Sagineedu, Sreenivasa Rao, Shaari, Khozirah, Stanslas, Johnson, Hancock, John F., Gorfe, Alemayehu A.

“…Aberrant signaling by oncogenic mutant rat sarcoma (Ras)proteins occurs in ∼15% of all human tumors, yet direct inhibition of Ras by small molecules has remained elusive. …”

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia by Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Tenen, Daniel G., Sanda, Takaomi, Fullwood, Melissa Jane

“…The oncogenic transcription factor TAL1 regulates the transcriptional program in T-ALL. …”
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Patterning of oncogenic Ras clustering in live cells using vertically aligned nanostructure arrays by Mu, Huanwen, Zeng, Yongpeng, Zhuang, Yinyin, Gao, Weibo, Zhou, Yong, Rajalingam, Krishnaraj, Zhao, Wenting

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Identification of epigenetic regulators cooperating with oncogene yorkie and notch in promoting tumorigenesis and metastasis in drosophila melanogaster by Qi, Le

“…Epigenetic regulators are emerging as cooperating factors that promote the activity of oncogenes in tumorigenesis and metastasis. In this study, we screened 19 epigenetic regulators in Polycomb group genes, Trithorax group genes, other related histone modifiers and chromatin remodeling complexes for oncogenic cooperation with known oncogene Yorkie and Notch using Drosophila TARGET system in wing imaginal discs. …”
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Molecular modelling of berberine derivatives as inhibitors of oncogenic signalling pathways in breast cancer cell lines by Kaboli, Parham Jabbarzadeh

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Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches by Quah, Shun Ying

“…Mutated K-Ras proteins are constitutively active with the GTPase activity being compromised. Oncogenic K-Ras is currently a valuable oncology target and its inhibition represents an important therapeutic strategy. …”
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A study of lipid-mediated clustering of oncogenic Ras proteins on cell membrane using nanotopography engineering by Mu, Huanwen

“…Dysregulation of Ras, a dominant oncogenic protein, in cell proliferation, differentiation, and survival contributes to ~20% of human cancers. …”
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An oncogenic role for transcription factor ERG in prostate cancer progression: promoting androgen-independent growth and survival. by Sng, Noel Yan Wei.

“…In this study, we sought to investigate the oncogenic role of ERG in two androgen-dependent cell lines, VCaP and LNCaP under androgen-depleted conditions. …”
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Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development by Aswad, Luay, Yenamandra, Surya Pavan, Ow, Ghim Siong, Grinchuk, Oleg, Ivshina, Anna V., Kuznetsov, Vladimir A.

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Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds by Ikram, Nazia, Mirza, Muhammad Usman, Vanmeert, Michiel, Froeyen, Matheus, Salo-Ahen, Outi M.H., Tahir, Muhammad, Qazi, Aamer, Ahmad, Sarfraz

“…The presented work aims to identify the potential multi-target inhibitors of oncogenic receptor tyrosine kinases (RTKs) and serine/threonine kinases (STKs). …”