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Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells
Published 2021-09-01Subjects: Get full text
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CDK5: an oncogene or an anti-oncogene: location location location
Published 2023-11-01“…The emerging theme suggests that CDK5’s role as an oncogene or anti-oncogene depends upon its subcellular localization. …”
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Oncogenes and the Origins of Leukemias
Published 2022-02-01Subjects: “…oncogenes…”
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Advances in Molecular Research of Oncogenes
Published 2023-04-01“…The isolation of the first human oncogene (HRAS), a critical breakthrough in cancer research, has occurred over forty years ago, and the identification of new pathogenic oncogenes has continuously grown since [...]…”
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RAS oncogenes direct metastasis
Published 2017-09-01“…RAS genes are cardinal driver oncogenes frequently and differentially mutated across bodily tumors. …”
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Differences in the profile of cytokine expression induced by implantation of oncogenic and non-oncogenic millipore filters
Published 2019-11-01“…For Nf-κB1 and Nf-κB2, Tgf-β and COX-2 (cyclooxygenase 2) the difference was significant, cells on non-oncogenic filters are expressed more then on oncogenic one’s.…”
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The case of oncogenic hypophosphatemic osteomalacia
Published 2020-09-01Subjects: Get full text
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Identification of an oncogenic RAB protein
Published 2017“…Two somatic RAB35 mutations found in human tumors generate alleles that constitutively activate PI3K/AKT signaling, suppress apoptosis, and transform cells in a PI3K-dependent manner. Furthermore, oncogenic RAB35 is sufficient to drive platelet-derived growth factor receptor α to LAMP2-positive endomembranes in the absence of ligand, suggesting that there may be latent oncogenic potential in dysregulated endomembrane trafficking.…”
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