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    Opioids and Their Receptors: Present and Emerging Concepts in Opioid Drug Discovery by Mariana Spetea, Helmut Schmidhammer

    Published 2020-12-01
    “…The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained throughout the years [...]…”
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    Opioid rotation with extended-release opioids: where should we begin? by Nalamachu S

    Published 2011-12-01
    “…Srinivas NalamachuInternational Clinical Research Institute and Pain Management Institute, Overland Park, KS, USAAbstract: Opioid rotation is a common and necessary clinical practice in the management of chronic non-cancer pain to improve therapeutic efficacy with the lowest opioid dose. …”
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    Opioids and Their Receptors: Present and Emerging Concepts in Opioid Drug Discovery II by Richard M. Van Rijn, Mariana Spetea

    Published 2022-05-01
    “…A few neurotransmitter systems have fascinated the research community, as muchas the opioid system (i.e., opioid ligands and their receptors) [...]…”
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    Mu Opioid Receptor Gene: New Point Mutations in Opioid Addicts by Amin Dinarvand, Ali Goodarzi, Nasim Vousooghi, Mehrdad Hashemi, Rasoul Dinarvand, Fahimeh Ostadzadeh, Ahad Khoshzaban, Mohammad-Reza Zarrindast

    Published 2014-02-01
    “…Introduction: Association between single-nucleotide polymorphisms (SNPs) in mu opioid receptor gene and drug addiction has been shown in various studies. …”
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    Opioid-Based vs opioid-free anesthesia in breast cancer surgery by Shraddha Naik, Avinash Bhosale, Dhanashree Kale, Pradeep B Patil

    Published 2023-01-01
    “…Result and Conclusion: We conclude that opioid-free anesthesia is “more effective in reducing the incidence of postoperative nausea and vomiting, produces stable hemodynamics, and reduces incidence of side effects when compared with opioid-based general anesthesia in patients undergoing breast cancer surgeries.”…”
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    Fentanyl Structure as a Scaffold for Opioid/Non-Opioid Multitarget Analgesics by Piotr F. J. Lipiński, Joanna Matalińska

    Published 2022-03-01
    “…In the present contribution we summarize the attempts in which fentanyl or its substructures were used as a μ-opioid receptor pharmacophoric fragment and a scaffold to which fragments related to non-opioid receptors were attached. …”
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    Opioid Use Disorder Education for Students and the Future of Opioid Overdose Treatment by Neha Balapal, Amala Ankem, Saishravan Shyamsundar, Shuhan He

    Published 2022-07-01
    “… Opioid use disorder (OUD) is a major public health concern in the United States. …”
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    Management of Opioid Addiction With Opioid Substitution Treatments: Beyond Methadone and Buprenorphine by Florence Noble, Florence Noble, Florence Noble, Nicolas Marie, Nicolas Marie, Nicolas Marie

    Published 2019-01-01
    “…With the opioid crisis in North America, opioid addiction has come in the spotlight and reveals the weakness of the current treatments. …”
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