Considerations in selecting rapid-onset opioids for the management of breakthrough pain by Smith HS

“…Various formulations of fentanyl – a rapid-onset opioid with short duration of action – are available for the management of BTP. …”
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Modeling dynamics of fatal opioid overdose by state and across time by R. Lyle Cooper, Janese Thompson, Ryan Edgerton, Julia Watson, Samuel A. MacMaster, Medhat Kalliny, Miranda M. Huffman, Paul Juarez, Patricia Mathews-Juarez, Mohammad Tabatabai, Karan P. Singh

Subjects: “…Opioids…”
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Abstract: Opioid Prescribing Patterns for Common Elective Hand Procedures by Nichole A. Joslyn, MD, Joel Solomon, MD PHD

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Endomorphins: Promising Endogenous Opioid Peptides for the Development of Novel Analgesics by Zheng-Hui Gu, Bo Wang, Zhen-Zhen Kou, Yang Bai, Tao Chen, Yu-Lin Dong, Hui Li, Yun-Qing Li

“…Endomorphin-1 (EM1) and endomorphin-2 (EM2) are two endogenous ligands that belong to the opioid peptide family and have the highest affinity and selectivity for the µ-opioid receptor (MOR). …”
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Perioperative Pain Management and Opioid Stewardship: A Practical Guide by Sara J. Hyland, Kara K. Brockhaus, William R. Vincent, Nicole Z. Spence, Michelle M. Lucki, Michael J. Howkins, Robert K. Cleary

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A biomarker of opioid-induced respiratory toxicity in experimental studies by Marieke Hellinga, Marijke Hyke Algera, Rutger van der Schrier, Elise Sarton, Monique van Velzen, Albert Dahan, Erik Olofsen, Marieke Niesters

“…Summary: Opioids are commonly used painkillers and drugs of abuse and have serious toxic effects including potentially lethal respiratory depression. …”
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Functional characteristics of the naked mole rat μ-opioid receptor. by Melanie Busch-Dienstfertig, Clarisse A Roth, Christoph Stein

“…While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. …”
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Optimal control of a multi-scale HIV-opioid model by Eric Numfor, Necibe Tuncer, Maia Martcheva

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Pills and the damage done: the opioid epidemic as man-made crisis by Rebecca McDonald, Desiree Eide, Svetlana Skurtveit, Svetlana Skurtveit, Thomas Clausen

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An answered call for aid? Cannabinoid clinical framework for the opioid epidemic by Krista Hammaker, Nathaniel Weathington, Joseph Maroon, Lawton W. Tang, Brian Donohue, Rachel Yehuda, Kenneth M. Ford, Myro Figura, Ben Kelmendi, Belinda Tan, Matthew W. Cook, Steven D. Factor, Laura Lagano, Henry Patrick Driscoll, Adam S. Howe, EunBit G. Cho, David M. Rabin

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Effects of Local Opioid Antagonist on Diabetic Fracture Rat Model by Jarrett D. Cain MSc, DPM, Michelle Titunick BA, Patricia McLaughlin PhD, Ian Zagon PhD

“…Four diabetic rats received opioid antagoinist (naltrexone) and calcium sulfate and all remaining rats received calcium sulfate with water only. …”
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INVESTIGATION OF INTERACTIONS BETWEEN DERMORPHIN ANALOGS AND µ-OPIOID RECEPTOR by AGNIESZKA KARCZYŃSKA, BARTŁOMIEJ ZABOROWSKI, MAGDALENA ŚLUSARZ

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Prescription opioid dispensing in Canada: an update on recent developments to 2018 by Wayne Jones, Lenka Vojtila, Paul Kurdyak, Benedikt Fischer

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The role of opioid peptides in the regulation of secretin-stimulated bile secretion by M. A. Medvedev, I. V. Roudin

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Pain management, prescription opioid mortality, and the CDC: is the devil in the data? by Schatman ME, Ziegler SJ

Subjects: “…prescription opioids…”
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Opioid Use Is Associated with ICU Delirium in Mechanically Ventilated Children by Gupta Neha, Woolley Allison, Talathi Saurabh, Davlyatov Ganisher, Colston Candice, Hayes Leslie

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The role of μ-opioid receptors in the regulation of hepatic secretory function by M. A. Medvedev, I. V. Rudin, A. F. Garayeva

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Opioids and Sepsis: Elucidating the Role of the Microbiome and microRNA-146 by Yaa Abu, Nicolas Vitari, Yan Yan, Sabita Roy

Subjects: “…opioids…”
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Long-Acting Injectable naltrexone for the Management of patients with Opioid Dependence by Kimberly L. Kjome, F. Gerard Moeller

“…Opioid dependence is a condition with serious clinical ramifications. …”
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The Impact of Pediatric Opioid-Related Visits on U.S. Emergency Departments by Tiffany Champagne-Langabeer, Marylou Cardenas-Turanzas, Irma T. Ugalde, Christine Bakos-Block, Angela L. Stotts, Lisa Cleveland, Steven Shoptaw, James R. Langabeer

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