Opioid use in the era of COVID-19: a multifaceted study of the opioid epidemic in Canada by Molly Hutchinson, Éric Lavigne, Éric Lavigne, Zachary Patterson

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Associations among Discharge Opioid Prescribing and Inpatient Postpartum Opioid Usage after Delivery by Ashley Veade, Tyler McKinnish, Ebony Carter, Adam Lewkowitz

Subjects: “…opioids…”
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The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse by Charles P. Schaefer, Margaret E. Tome, Thomas P. Davis

Subjects: “…Opioids…”
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High-Dose Opioid Prescribing and Opioid-Related Hospitalization: A Population-Based Study. by Kimberly Fernandes, Diana Martins, David Juurlink, Muhammad Mamdani, J Michael Paterson, Luke Spooner, Samantha Singh, Tara Gomes

“…To examine the impact of national clinical practice guidelines and provincial drug policy interventions on prevalence of high-dose opioid prescribing and rates of hospitalization for opioid toxicity.Interventional time-series analysis.Ontario, Canada, from 2003 to 2014.Ontario Drug Benefit (ODB) beneficiaries aged 15 to 64 years from 2003 to 2014.Publication of Canadian clinical practice guidelines for use of opioids in chronic non-cancer pain (May 2010) and implementation of Ontario's Narcotics Safety and Awareness Act (NSAA; November 2011).Three outcomes were explored: the rate of opioid use among ODB beneficiaries, the prevalence of opioid prescriptions exceeding 200 mg and 400 mg morphine equivalents per day, and rates of opioid-related emergency department visits and hospital admissions.Over the 12 year study period, the rate of opioid use declined 15.2%, from 2764 to 2342 users per 10,000 ODB eligible persons. …”
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Age differences in heroin and prescription opioid abuse among enrolees into opioid treatment programs by Fong Chunki, Rosenblum Andrew, Cleland Charles M, Maxwell Carleen

“…<p>Abstract</p> <p>Background</p> <p>In the United States, among those entering opioid treatment programs (OTPs), prescription opioid (PO) abusers tend to be younger than heroin users. …”
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Patterns of Opioid and Non-Opioid Analgesic Consumption in Patients with Post-COVID-19 Conditions by Pilar Carrasco-Garrido, Domingo Palacios-Ceña, Valentín Hernández-Barrera, Isabel Jiménez-Trujillo, Carmen Gallardo-Pino, Cesar Fernández-de-las-Peñas

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Pharmacologic and Clinical Considerations of Nalmefene, a Long Duration Opioid Antagonist, in Opioid Overdose by Amber N. Edinoff, Catherine A. Nix, Tanner D. Reed, Elizabeth M. Bozner, Mark R. Alvarez, Mitchell C. Fuller, Fatimah Anwar, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye

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Comparison of opioid-based and opioid-free TIVA for laparoscopic urological procedures in obese patients by Shaman Bhardwaj, Kamakshi Garg, Sumeet Devgan

“…Material and Methods: In this prospective, randomized, blinded controlled study, patients were randomized to receive either opioid-based (opioid group) or opioid-free (opioid-free group) anesthesia. …”
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Prolonged Opioid Use Among Opioid-Naive Women Undergoing Breast Reconstructive Surgery by Ankhita R. Samuel, Laura Fuhr, Brent R. DeGeorge Jr, Jonathan Black, Christopher Campbell, John T. Stranix

Subjects: “…prolonged opioid use…”
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Which idea is better with regard to immune response? Opioid anesthesia or opioid free anesthesia by Lisowska B, Jakubiak J, Siewruk K, Sady M, Kosson D

Subjects: “…opioids…”
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Non-Opioid Substances Acute Poisonings with Suicidal Intent in Patients with Opioid Use Disorder by Natasha K. Simonovska, Vesna V. Stefanovska, Aleksandra Babulovska

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Illicit opioid use following changes in opioids prescribed for chronic non-cancer pain. by Phillip O Coffin, Christopher Rowe, Natalie Oman, Katie Sinchek, Glenn-Milo Santos, Mark Faul, Rita Bagnulo, Deeqa Mohamed, Eric Vittinghoff

“…We hypothesized that reduced access to prescribed opioid pain relievers among patients previously reliant upon opioid pain relievers would result in increased illicit opioid use.…”
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Impact of Prior Therapeutic Opioid Use by Emergency Department Providers on Opioid Prescribing Decisions by Adam C Pomerleau, Jeanmarie Perrone, Jason Hoppe, Matthew Salzman, Paul Weiss, Lewis Nelson

Subjects: “…Opioids…”
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Comparing Opioid with Opioid-free Anesthesia Technique in Neonates Undergoing Tracheoesophageal Fistula Repair by Maria Paul, Charu Bamba, Vinay V., Bhavya Krishna, Bharani Kumar B.

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Risk for opioid misuse in chronic pain patients is associated with endogenous opioid system dysregulation by Javier Ballester, Anne K. Baker, Ilkka K. Martikainen, Vincent Koppelmans, Jon-Kar Zubieta, Tiffany M. Love

“…Abstract µ-Opioid receptors (MOR) are a major target of endogenous and exogenous opioids, including opioid pain medications. …”
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Intraoperative Use of Remifentanil and Opioid Induced Hyperalgesia/Acute Opioid Tolerance - Systematic review by Sang Hun eKim, Nicoleta eStoicea, Suren eSoghomonyan, Sergio Daniel Bergese, Sergio Daniel Bergese

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What is the benefit of inconsistent opioid agonist treatment in patients with prescription opioid use disorder? by R. Weiss, M. L. Griffin

“…Our longitudinal research has shown opioid abstinence to be associated most strongly with opioid agonist/partial agonist treatment. …”
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Crosstalk between Opioid and Anti-Opioid Systems: An Overview and Its Possible Therapeutic Significance by Ewa Gibula-Tarlowska, Jolanta H. Kotlinska

Subjects: “…anti-opioids…”
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Pregnant women misusing opioids: Depression, anxiety, stress, and neonatal opioid withdrawal syndrome by Samantha Noose Glovak, MA, Stephanie B. Kors, MA, Andrea M. Gorrondona, MA, Gretchen Kurdziel-Adams, PhD, Craig V. Towers, MD, Kimberly B. Fortner, MD, Jenny Macfie, PhD

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Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence. by Bastian Rosner, Jessica Neicun, Justin Christopher Yang, Andres Roman-Urrestarazu

“…The increase of opioid prescription over time has led to higher numbers of prescription opioid misuse, abuse and opioid-related deaths in most developed OECD (Organisation for Economic Co-operation and Development) countries around the world. …”
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