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421
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Cell contraction induces long-ranged stress stiffening in the extracellular matrix
Published 2018“…We decipher this remarkable behavior by introducing nonlinear stress inference microscopy (NSIM), a technique to infer stress fields in a 3D matrix from nonlinear microrheology measurements with optical tweezers. Using NSIM and simulations, we reveal large long-ranged cell-generated stresses capable of buckling filaments in the matrix. …”
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Article -
423
Aging Changes Cell Mechanics and Dynamics with a Backbone of Cytoplasmic Crowding
Published 2024“…Using particle fluctuation, optical tweezers, and force spectrum microscopy, we demonstrate that aging halves motion inside the cytoplasm due to doubled stiffness, while active forces remain statistically similar. …”
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Thesis -
424
Multiscale Modeling of Red Blood Cell Mechanics and Blood Flow in Malaria
Published 2012“…The simulated elastic deformations of parasitized RBCs match those obtained in optical-tweezers experiments for different stages of intra-erythrocytic parasite development. …”
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425
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426
Near-field Raman imaging with the use of dielectric microspheres.
Published 2010“…The microsphere was held into position by the same laser incident on the surface through the well-known optical tweezers mechanism. The purpose of this study is to further improve this technique and explore its potential applications in the field of plasmonics. …”
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Final Year Project (FYP) -
427
Unravelling the roles of non-Watson-Crick and triplex structures in regulating RNA folding dynamics and function
Published 2016“…The SRV-1 frameshifting pseudoknot is located in the overlapping region of gag and pol genes and plays critical roles in stimulating frameshifting. Using optical tweezers, we studied the mechanical properties of a series of pseudoknots derived from the wildtype SRV-1 frameshifting pseudoknot. …”
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Thesis -
428
Cooperative and mobile manipulation of multiple microscopic objects based on micro-hands and laser-stage control
Published 2019“…While various techniques have been developed for manipulation of biological cells or micro-objects using optical tweezers, the performance and feasibility of these techniques are mostly dependent on the physical properties of the target objects to be manipulated. …”
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Journal Article -
429
Dynamics of driven colloidal systems in one-dimensional potential energy landscapes
Published 2014“…Experiments are conducted using colloids driven by solvent flow or piezo-stage, optical tweezers, magnetic fields, and video-microscopy. …”
Thesis -
430
How to design, optimise and implement a fibre-tip Fabry-Pérot cavity for quantum networks of atoms and photons
Published 2021“…For the latter, we design a scheme that allows for a 2D reconfigurable array of atoms, held in the cavity mode by holographically-generated optical tweezers. Our particular design will allow us to move atoms independently of one another.…”
Thesis -
431
Fabrication of Chiral 3D Microstructure Using Tightly Focused Multiramp Helico-Conical Optical Beams
Published 2022-10-01“…Our results enrich the means of two-photon polymerization technology and provide a simple and stable way for the micromachining of chiral microstructures, which may have a wide range of applications in optical tweezers, optical communications, and metasurfaces.…”
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Article -
432
Miniature tunable Airy beam optical meta-device
Published 2024-02-01“…The proposed meta-device addresses the existing limitations and lays the foundation for broadening the applicability of Airy beams across diverse domains, encompassing light-sheet microscopy, laser fabrication, optical tweezers, etc.…”
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433
Optical forces in photonic Weyl system
Published 2022-01-01“…In this work, we apply the photonic Weyl metamateirals into the optical tweezers. Based on the effective medium approach, the optical force generated by the body state of the Weyl metamaterial is systematically investigated. …”
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434
Assessing Radiation Effects on Chemo-Treated BT20 and 4T1 Breast Cancer, and Neuroblastoma Cell Lines: A Study of Single and Multiple-Cell Ionization via Infrared Laser Trapping
Published 2024-03-01“…Leveraging laser trapping techniques, biocompatible nanoparticles, and advanced optical tweezers opens promising avenues for personalized and effective cancer therapy approaches.…”
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435
Superchirality induced enhanced circular dichroism spectroscopy via multi-beam superposition
Published 2023-09-01“…Furthermore, we demonstrate that this technique is suitable to combine optical tweezers and CD spectroscopy. Based on three-beam superposition configuration, we explore the optical force and CD effects from single chiral nanoparticle, which are introduced into the optical standing wave formed by a flat mirror. …”
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436
Controllable plasmonic vortex sequence with on-chip discrete-slit-based metalens
Published 2023-01-01“…This work has potential applications in on-chip optical information processing, integrated optical communications, and optical tweezers.…”
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437
Dynamic Deformation Measurement of an Intact Single Cell via Microfluidic Chip with Integrated Liquid Exchange
Published 2023-05-01“…A single cell is manipulated and positioned between a pushing probe and a force sensor probe using optical tweezers. These two on-chip probes were designed to capture and deform the cells. …”
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438
Compromised Biomechanical Properties, Cell–Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation
Published 2021-08-01“…In mutant-expressing fibroblasts, these nanotubes were weakened with altered mechanical properties as shown by atomic force microscopy (AFM) and optical tweezers. These outcomes complement prior investigations on <i>LMNA</i> mutant cardiomyocytes and suggest that the <i>LMNA</i> D192G mutation impacts the biomechanical properties of both cardiomyocytes and cardiac fibroblasts. …”
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439
Structure and assembly of bacteriophage T4 head
Published 2010-12-01“…Single molecule optical tweezers and fluorescence studies showed that the T4 motor packages DNA at a rate of up to 2000 bp/sec, the fastest reported to date of any packaging motor. …”
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440
Chemical Sensing and Analysis with Optical Nanostructures
Published 2023-09-01“…Using these properties, label-free plasmonic sensors, nano-optical tweezers, and plasmonic matrix-assisted laser desorption/ionization have also been demonstrated in the past two decades. …”
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