Cellular mechanisms and function of hippocampal gamma oscillations by Antonoudiou, P

“…Here, we took advantage of optogenetic techniques to test the involvement of parvalbumin- and somatostatinexpressing interneurons in a well studied model of carbachol-induced gamma oscillations in the hippocampal CA3 in vitro. …”

Monitoring and controlling GABAergic interneuron subtypes during epileptiform activity by Calin, A

“…To investigate the impact of this process, I use a light-activated optogenetic tool to induce brief hyperpolarisations of the PV interneuron membrane potential. …”

Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism by Jae Hoon Jeong, Dong Kun Lee, Clemence Blouet, Henry H. Ruiz, Christoph Buettner, Streamson Chua, Jr., Gary J. Schwartz, Young-Hwan Jo

“…Physiological studies in response to optogenetic stimulation of DMH cholinergic neurons were combined with gene expression and immunocytochemical analyses. …”
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Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice by Yi Cao, Yi Cao, Chongyang Sun, Jianyu Huang, Jianyu Huang, Peng Sun, Peng Sun, Lulu Wang, Shuyu He, Jianxiang Liao, Zhonghua Lu, Yi Lu, Cheng Zhong

“…In particular, the dorsal dentate gyrus and CA3 somatostatin-positive neurons and dorsal lateral septum cholecystokinin-positive neurons are selectively vulnerable to damage after temporal lobe epilepsy. Optogenetic activation of the hippocampal glutamatergic neurons or chemogenetic inhibition of the hippocampal somatostatin neurons directly disrupts RA, suggesting that an excitation/inhibition imbalance in the dHPC dorsal lateral septum circuit results in the impairment of RA behavior. …”
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Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors by Toshiaki Suzuki, Nao Morimoto, Nao Morimoto, Akinori Akaike, Fumitaka Osakada, Fumitaka Osakada, Fumitaka Osakada, Fumitaka Osakada

“…Pseudotyping of RVΔG with the foreign envelope EnvA permits expression of transgenes such as fluorescent proteins, genetically-encoded sensors, or optogenetic tools in cells expressing TVA, a cognate receptor for EnvA. …”
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Gender difference in the associations between health literacy and problematic mobile phone use in Chinese middle school students by Dan-Lin Li, Sizhe Wang, Daoxu Zhang, Rong Yang, Jie Hu, Yanni Xue, Xuexue Huang, Yuhui Wan, Chen-Wei Pan, Jun Fang, Shichen Zhang

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Advancing homogeneous networking principles for the development of fatigue-resistant, low-swelling and sprayable hydrogels for sealing wet, dynamic and concealed wounds in vivo by Yi Zhang, Yanjun Pan, Ronghang Chang, Kangli Chen, Kun Wang, Haoqi Tan, Meng Yin, Changsheng Liu, Xue Qu

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Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A2A-Dopamine D2 Receptor Heterotetramers and Adenylyl Cyclase by Sergi Ferré, Jordi Bonaventura, Wendy Zhu, Candice Hatcher-Solis, Jaume Taura, Jaume Taura, César Quiroz, Ning-Sheng Cai, Estefanía Moreno, Verónica Casadó-Anguera, Alexxai V. Kravitz, Kimberly R. Thompson, Dardo G. Tomasi, Gemma Navarro, Arnau Cordomí, Leonardo Pardo, Carme Lluís, Carmen W. Dessauer, Nora D. Volkow, Vicent Casadó, Francisco Ciruela, Francisco Ciruela, Diomedes E. Logothetis, Daniel Zwilling

“…This is mostly achieved by the strategic co-localization of different adenosine and dopamine receptor subtypes in the two populations of striatal efferent neurons, striatonigral and striatopallidal, that give rise to the direct and indirect striatal efferent pathways, respectively. With optogenetic techniques it has been possible to dissect a differential role of the direct and indirect pathways in mediating “Go” responses upon exposure to reward-related stimuli and “NoGo” responses upon exposure to non-rewarded or aversive-related stimuli, respectively, which depends on their different connecting output structures and their differential expression of dopamine and adenosine receptor subtypes. …”
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DPY30 acts as an ASH2L-specific stabilizer to stimulate the enzyme activity of MLL family methyltransferases on different substrates by Lijie Zhao, Naizhe Huang, Jun Mencius, Yanjing Li, Ying Xu, Yongxin Zheng, Wei He, Na Li, Jun Zheng, Min Zhuang, Shu Quan, Yong Chen

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Investigating circuits underlying acetylcholine-evoked striatal dopamine release in health and disease by Kosillo, P

“…</p> <p>Synchronous activity in a small population of striatal cholinergic interneurons (ChIs) was previously shown to directly drive striatal DA release. Here using optogenetic approach I explore physiological relevance of ChI-evoked drive of striatal DA by examining whether corticostriatal and thalamostriatal afferents to ChIs can trigger ACh-evoked DA events. …”

Comparative analyses of dopaminergic signalling in the mouse brain by Marijatta, F

“…The data reported a positive linear relationship between optogenetically evoked dopaminergic neuron firing and striatal dopamine release, which suggests a close relationship between these two modes of dopaminergic signalling. …”

Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function by Man Qi, Shenghui Chu, Wenxuan Wang, Xianglei Fu, Chao Jiang, Liang Zhang, MD Hasan Ali, Yating Lu, Mengwei Jia, Dilraba Ubul, Hui Tang, Jian Li, Min Liu

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A suture-free, shape self-adaptive and bioactive PEG-Lysozyme implant for Corneal stroma defect repair and rapid vision restoration by Hang Zhou, Shaohua Zhang, Miao Lei, Yixin Cai, Honglei Wang, Jianguo Sun, Jingyuan Cui, Changsheng Liu, Xue Qu

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Slowly reducible genetically encoded green fluorescent indicator for in vivo and ex vivo visualization of hydrogen peroxide by Piatkevich, Kiryl

“…In contrast to HyPer3, NeonOxIrr could visualize optogenetically produced ROS in HEK293T cells. In neuronal cultures, NeonOxIrr preserved its high 3.2-fold dynamic range to H2O2 and slow 198 min reduction half-time. …”
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Ascl1 phospho-site mutations enhance neuronal conversion of adult cortical astrocytes in vivo by Hussein Ghazale, Hussein Ghazale, EunJee Park, EunJee Park, Lakshmy Vasan, Lakshmy Vasan, James Mester, James Mester, Fermisk Saleh, Fermisk Saleh, Andrea Trevisiol, Andrea Trevisiol, Dawn Zinyk, Vorapin Chinchalongporn, Vorapin Chinchalongporn, Mingzhe Liu, Mingzhe Liu, Taylor Fleming, Taylor Fleming, Oleksandr Prokopchuk, Natalia Klenin, Deborah Kurrasch, Maryam Faiz, Bojana Stefanovic, Bojana Stefanovic, JoAnne McLaurin, JoAnne McLaurin, Carol Schuurmans, Carol Schuurmans, Carol Schuurmans

“…Finally, we co-transduced an AAV expressing ChR2-(H134R)-YFP, an optogenetic actuator. After channelrhodopsin photostimulation, we found that Ascl1SA6 co-transduced astrocytes exhibited a significantly faster decay of evoked potentials to baseline, a neuronal feature, when compared to iCre control cells. …”
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Interrogation and control of mammalian transcription by Konermann, Silvana

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The mechanisms of reliable coding in mouse visual cortex by Rikhye, Rajeev V. (Rajeev Vijay)

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