Comparative clinical significance and biological roles of PFKFB family members in oral squamous cell carcinoma by Kai-Fang Hu, Chih-Wen Shu, Cheng-Hsin Lee, Ching-Jiunn Tseng, Yu-Hsiang Chou, Pei-Feng Liu

“…However, their roles in oral squamous cell carcinoma (OSCC), the most common type of oral cancer, are still unknown. Methods We compared the gene expression levels of PFKFB family members and analyzed their clinical significance in oral cancer patients, whose clinical data were obtained the Cancer Genome Atlas database. …”
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Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways by Hsin-Yu Ho, Ping-Ju Chen, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin, Ming-Ju Hsieh, Mu-Kuan Chen

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Knowledge and Attitudes of Nursing Students Towards Smokeless Tobacco and Areca Nut Control in Central Province of Sri Lanka by PVKS Hettiarachchi, Primal Jayasooriya, Hemantha Amarasinghe, BSMS Siriwardena, Deepashika Wijerathne, Samantha Kithalawa arachchi, WM Tilakaratne, Ruwan Jayasinghe

“…Results: Results were analyzed according to the 3 main areas of the assessment, i.e knowledge related to Oral cancer, knowledge related to SLT, its effects and cessation practices and attitudes regarding SLT cessation counselling. …”
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The Tumor Suppressor TGFBR3 Blocks Lymph Node Metastasis in Head and Neck Cancer by Wei-Yu Fang, Yi-Zih Kuo, Jang-Yang Chang, Jenn-Ren Hsiao, Hung-Ying Kao, Sen-Tien Tsai, Li-Wha Wu

“…In this study, we observed a down-regulation of <i>TGFBR3</i> in oral cancer, a subtype of head and neck cancer (HNC), and patients with low <i>TGFBR3</i> had poor clinical outcomes. …”
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MDM2 SNP309 does not confer an increased risk to oral squamous cell carcinoma but may modulate the age of disease onset by Hamid, S., Yang, Y.H., Peng, K.N.L., Ismail, S.M., Zain, R.B., Lim, K.P., Wan Mustafa, W.M., Abraham, M.T., Teo, S.H., Cheong, S.C.

“…We have previously shown that overexpression of MDM2 is a common event in oral cancers. In the present study, we determined the association between the MDM2 SNP309 polymorphism and oral cancer in 207 oral cancer patients and 116 normal subjects. …”
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Perspectives of San Juan healthcare practitioners on the detection deficit in oral premalignant and early cancers in Puerto Rico: a qualitative research study by Baek Linda S, Vélez Himilce, Buxó Carmen J, Psoter Walter J, Vélez Vega Carmen M, Morse Douglas E, Elias Augusto, Ayendez Melba

“…</p> <p>Results</p> <p>Key informant-identified factors that likely contribute to the detection deficit include: many practitioners are deficient in knowledge regarding oral cancer and precancer; oral cancer screening examinations are limited regarding which patients receive them and the elements included. …”
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Emerging Role of Decoy Receptor-2 as a Cancer Risk Predictor in Oral Potentially Malignant Disorders by Lucas de Villalaín, Saúl Álvarez-Teijeiro, Tania Rodríguez-Santamarta, Álvaro Fernández del Valle, Eva Allonca, Juan P. Rodrigo, Juan Carlos de Vicente, Juana M. García-Pedrero

“…Correlations between protein marker expression, histological grade and oral cancer risk were assessed. DcR2, DEC1 and Ki67 protein expressions were found to correlate significantly with increased oral cancer risk, and also with an increased grade of dysplasia. …”
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Exploring the potential of dietary factors and plant extracts as chemopreventive agents in oral squamous cell carcinoma treatment by Madhav Kumar, Abhimanyu Kumar Jha

“…Oral cancer, particularly oral squamous cell carcinoma (OSCC), is a prevalent malignancy having a significant fatality rate worldwide. …”
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Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin. by Pachiyappan Kamarajan, Islam Ateia, Jae M Shin, J Christopher Fenno, Charles Le, Ling Zhan, Ana Chang, Richard Darveau, Yvonne L Kapila

“…Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. …”
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Ultrasensitive detection of cancer biomarkers in the clinic by use of a nanostructured microfluidic array by Malhotra, R., Patel, V., Chikkaveeraiah, B.V., Munge, B.S., Cheong, S.C., Zain, R.B., Abraham, M.T., Dey, D.K., Gutkind, J.S., Rusling, J.F.

“…Normalized means of the four protein levels in 78 oral cancer patient serum samples and 49 controls gave clinical sensitivity of 89 and specificity of 98 for oral cancer detection, demonstrating high diagnostic utility. …”
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Oral Equilibrium in Cachexia by Deepthi Darwin, Renita Lorina Castelino, Gogineni Subhas Babu, Mohamed Faizal Asan, Anand Shankar Sarkar, Soundarya Shaktivel

“…Oral cancer, a part of head-and-neck cancer (HNC), is associated with a high risk of cancer-associated weight loss causing cachexia which is still an understudied illness. …”
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Pleomorphic rhabdomyosarcoma of the tongue in adult mimicking oral squamous cell carcinoma by Rahmi Amtha, Firstine Kelsi Hartanto, Walta Gautama, Haizal Mohd Hussaini

“…Background: Oral cancer is one of the sixth most common cancers in human, and oral squamous cell carcinoma (OSCC) is the most common type of oral cancer. …”
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The Wnt Signaling Pathway Inhibitors Improve the Therapeutic Activity of Glycolysis Modulators against Tongue Cancer Cells by Robert Kleszcz, Jarosław Paluszczak

“…The results point to the therapeutic potential of the combination of low concentrations of glycolytic modulators with Wnt pathway inhibitors in oral cancer cells.…”
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Asiatic Acid, Extracted from <i>Centella asiatica</i> and Induces Apoptosis Pathway through the Phosphorylation p38 Mitogen-Activated Protein Kinase in Cisplatin-Resistant Nasophar... by Yen-Tze Liu, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin, Yi-Ting Hsi, Ming-Ju Hsieh, Mu-Kuan Chen

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Advances of Salivary Proteomics in Oral Squamous Cell Carcinoma (OSCC) Detection: An Update by Rabia Sannam Khan, Zohaib Khurshid, Shazia Akhbar, Syed Faraz Moin

“…Oral cancer refers to malignancies that have higher morbidity and mortality rates due to the late stage diagnosis and no early detection of a reliable diagnostic marker, while oral squamous cell carcinoma (OSCC) is amongst the world’s top ten most common cancers. …”
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Dehydrocrenatidine Induces Liver Cancer Cell Apoptosis by Suppressing JNK-Mediated Signaling by Bharath Kumar Velmurugan, Ming-Ju Hsieh, Chia-Chieh Lin, Hsin-Yu Ho, Ming-Chang Hsieh

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Denture-Induced carcinoma in NSND patients: A case report by Narmatha Namachivayam, Asokan Sathyamoorthy

“…Oral squamous cell carcinoma is the most common type of oral cancer with multi-factorial causes. Chronic irritation of oral mucosa from ill-fitting dentures has often been mentioned as a contributing factor in the development of oral cancer. …”
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Niclosamide and Pyrvinium Are Both Potential Therapeutics for Osteosarcoma, Inhibiting Wnt–Axin2–Snail Cascade by Young Yi, Young Mi Woo, Kyu Ho Hwang, Hyun Sil Kim, Sang Hyeong Lee

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Immunoregulatory Markers in Human Saliva – A Non-Invasive Approach in the Diagnosis of Oral Precancerous and Cancerous Lesions by Bolyarova T., Mihailova-Kandilarova S., Stanimirov P., Yankova P., Adamov A., Mihaylova Z.

“…Currently, the diagnosis of oral cancer is based on clinical examination and histopathological analysis. …”
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Comparison of Oral Aerobic Bacterial Profile in Patients with Oral Squamous Cell Carcinoma and Patients with Oral Pre Cancerous Lesions, Attending Tertiary Care Centre in Rajasthan by Aditi Agarwal, Rajni Sharma, Navya Sharma

“…Oral cancer rates are rising rapidly over the globe. …”
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