Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents—Does Fibroblast Senescence Play a Role? by Pangzhen Zhang, Nathaniel Quan En Chua, Simon Dang, Ashleigh Davis, Kah Wee Chong, Stephen S. Prime, Nicola Cirillo

“…Our study emphasizes that the characterization of the detrimental or protective effects of specific BQ ingredients may facilitate the development of targeted BQ formulations to prevent and/or treat potentially malignant oral disorders and oral cancer in BQ users.…”
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In Vitro Properties for Bioceramics Composed of Silica and Titanium Oxide Composites by I-Hao Chen, Meng-Jia Lian, Wei Fang, Bo-Rui Huang, Tzu-Hao Liu, Jhih-An Chen, Chih-Ling Huang, Tzer-Min Lee

“…It is important for oral and maxillofacial surgeons to repair craniofacial defects on oral cancer patients or patients with congenital problems. …”
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Antioxidant and Anticancer Potential of Bioactive Compounds from <i>Rhinacanthus nasutus</i> Cell Suspension Culture by Pattralak Songserm, Poramaporn Klanrit, Poramate Klanrit, Jutarop Phetcharaburanin, Pornthap Thanonkeo, Jirawan Apiraksakorn, Khamphee Phomphrai, Preekamol Klanrit

“…In addition, the in vitro cytotoxicity revealed by the MTT assay demonstrated potent antiproliferative effects against the oral cancer cell lines ORL-48 and ORL-136 in a dose-dependent manner. …”
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Experimental study of cognitive function against the background of partial food derivation and its correction by A.A. Kushta

“…Tumors of the head and neck account for a significant percentage of all oncopathology. Oral cancer is most often diagnosed. The location of the tumor and its invasion causes swallowing disorders in the preoperative period, which is exacerbated in the postoperative period due to bulky defects. …”
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Unraveling the Risk Factors and Etiology of the Canine Oral Mucosal Melanoma: Results of an Epidemiological Questionnaire, Oral Microbiome Analysis and Investigation of Papillomavi... by Joyce Pires de Carvalho, Marcella Collaneri Carrilho, Denner Santos dos Anjos, Carolina Dagli Hernandez, Laura Sichero, Maria Lúcia Zaidan Dagli

“…Oral mucosal melanoma (OMM) is the most common oral cancer in dogs and is very aggressive in this species; its risk factors and etiology are yet to be determined. …”
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The Follow-Up Necessity in Human Papilloma Virus-Positive vs. Human Papilloma Virus-Negative Oral Mucosal Lesions: A Retrospective Study by Armina Rushiti, Chiara Castellani, Alessia Cerrato, Marny Fedrigo, Luca Sbricoli, Eriberto Bressan, Annalisa Angelini, Christian Bacci

“…The correlation between high-risk HPV and oral cancer is still controversial. HPV-related lesions of the oral cavity are frequent and, in most cases, benign. …”
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Evaluation of differential white blood cell count and cheek pouch epithelium in 7,12-dimethylbenza[a]anthracene hamster carcinogenesis model, managed with three phytochemicals by Darwish Mahmoud, Hassan Magda, Maria Ola M.

“…Discussion: The three phytochemicals showed different levels of protection against DMBA carcinogenic activity, more specifically, TQ and NS had higher therapeutic potential and might be used for treatment and/or preventive management of oral cancer in the future. Conclusion: However, further investigations are required to address the mechanism of action and feasibility of clinical application of each phytochemical.…”
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A 16-gene signature predicting prognosis of patients with oral tongue squamous cell carcinoma by Zeting Qiu, Wei Sun, Shaowei Gao, Huaqiang Zhou, Wulin Tan, Minghui Cao, Wenqi Huang

“…Background Oral tongue squamous cell carcinoma (OTSCC) is the most common subtype of oral cancer. A predictive gene signature is necessary for prognosis of OTSCC. …”
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Prognostic role of CD11b + myeloid-derived suppressor cells in oral squamous cell carcinoma by Yue Jiang, Chenxing Wang, Yanling Wang, Wei Zhang, Laikui Liu, Jie Cheng

“…Material and methods A total of 144 eligible OSCC samples from a tertiary referral oral cancer center were retrospectively collected. Intensities of CD11b + MDSCs at the tumor center (CT) and invasive margin (IM) in OSCC samples were detected by immunohistochemistry and automatically quantified using Image J software. …”
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Using the Theory of Planned Behavior to Explain and Predict Areca Nut Use Among Adolescents in India: An Exploratory Study by Gupte HA, Chatterjee N, Mandal G

“…Himanshu A Gupte,1 Nilesh Chatterjee,1 Gauri Mandal2 1Narotam Sekhsaria Foundation, Mumbai, Maharashtra, India; 2Salaam Bombay Foundation, Mumbai, Maharashtra, IndiaCorrespondence: Nilesh Chatterjee, Narotam Sekhsaria Foundation, First Floor, Nirmal Building, Nariman Point, Mumbai, 400 021, India, Tel +91-9819472736, Email nileshchatterjee100@gmail.comContext: Areca nut, used alone or in combination with tobacco, contributes to the high oral cancer burden in India. Used widely by adolescents, who perceive it as a harmless substance, areca nut is addictive and considered a precursor to tobacco use. …”
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Applications of Hydrogels in Drug Delivery for Oral and Maxillofacial Diseases by Lijia Liu, Dan Wu, Heng Tu, Mengjiao Cao, Mengxin Li, Li Peng, Jing Yang

“…This paper reviews the application and research progress of hydrogel-based drug delivery systems in the treatment of oral and maxillofacial diseases such as caries, endodontic diseases, periodontal diseases, maxillofacial bone diseases, mucosal diseases, oral cancer, etc. The characteristics and applications of hydrogels and drug-delivery systems employed for the treatment of different diseases are discussed in order to provide a reference for further research on hydrogel drug-delivery systems in the future.…”
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Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents by Powell, Geralle, Chen, Julie, Goldberg, Manijeh Nazari, Manzi, Aaron, Aydin, Erkin, Singh, Gurtej, Khoshkenar, Payam, Birdi, Amritpreet Kaur, LaPorte, Brandon, Krauskopf, Alejandro A., Langer, Robert S

“…CSM is intended to be administered topically and locally to mucosal tissues, with its initial indication being oral cancer (OC). Currently, intravenous (IV) administered CDDP is the gold standard chemotherapeutic agent used in the treatment of OC. …”
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The Current and Potential Application of Medicinal Cannabis Products in Dentistry by Lowe, Henry, Toyang, Ngeh, Steele, Blair, Bryant, Joseph, Ngwa, Wilfred, Nedamat, Kaveh

“…The most prevalent dental and oral health conditions are tooth decay (otherwise referred to as dental caries/cavities), oral cancers, gingivitis, periodontitis, periodontal (gum) disease, Noma, oro-dental trauma, oral manifestations of HIV, sensitive teeth, cracked teeth, broken teeth, and congenital anomalies such as cleft lip and palate. …”
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Model-based spectroscopic analysis of the oral cavity: impact of anatomy by McGee, Sasha, Mirkovic, Jelena, Mardirossian, Vartan, Elackattu, Alphi, Yu, Chung-Chieh, Kabani, Sadru, Gallagher, George, Pistey, Robert, Galindo, Luis H., Badizadegan, Kamran, Wang, Zimmern, Dasari, Ramachandra Rao, Feld, Michael S., Grillone, Gregory

“…This work provides an important foundation for guiding the development of spectroscopic-based diagnostic algorithms for oral cancer.…”
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Gene expression profiling reveals biological pathways responsible for phenotypic heterogeneity between UK and Sri Lankan oral squamous cell carcinomas by Saeed, A.A., Sims, A.H., Prime, S.S., Paterson, Ian Charles, Murray, P.G., Lopes, V.R.

“…Results: The gene expression profiles of UK and Sri Lankan OSCC are similar in many respects to other oral cancer expression profiles reported in the literature and were mainly similar to each other. …”
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Dental patient knowledge about the effects of smoking and attitudes about the role of dentists in smoking cessation by Yahya, Nurul Asyikin, Saub, Roslan, Md Nor, Mariani, Yusoff, Noriah

“…Significantly more participants (p < 0.001) who never smoked (84.5%) knew smoking can cause oral cancer than smokers (66.7%). Significantly more participants (p < 0.001) who never smoked (86.7%) knew smoking can cause lung cancer than smokers (69.7%). …”
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Photobiomodulation Therapy in Oral Mucositis and Potentially Malignant Oral Lesions: A Therapy Towards the Future by Reem Hanna, Snehal Dalvi, Stefano Benedicenti, Andrea Amaroli, Tudor Sălăgean, Ioana Delia Pop, Doina Todea, Ioana Roxana Bordea

“…Photobiomodulation therapy (PBMT) is an effective treatment modality, which has the significant advantage of enhancing a patient’s quality of life (QoL) by minimising the side effects of oral cancer treatments, as well as assisting in the management of potentially cancerous lesions. …”
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A comprehensive review on the availability of bioactive compounds, phytochemicals, and antioxidant potential of plum (Prunus Domestica) by Hudda Ayub, Muhammad Nadeem, Muhammad Mohsin, Saadia Ambreen, Faima atta Khan, Sadaf Oranab, Muhammad abdul Rahim, Muhammad Zubair khalid, Eliasse Zongo, Mehwish Zarlasht, Sami Ullah

“…It is also effective in the treatment of lung and oral cancer. The consumption of plums boosts human health and prevents many diseases. …”
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Malignant Transformation Rate in Chinese Patients with Oral Leukoplakia: a Meta-analysis by YANG Ling, HOU Lili, CHEN Weihong, WENG Ximei, LUO Shasha, XIA Jialin

“…Background Oral cancer is highly prevalent, which is often caused by oral potentially malignant disorders, and oral leukoplakia is the most common. …”
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The role of urologists in smoking cessation: what they can do for urological cancer patients by Krzysztof Przewozniak, Roman Sosnowski

“…Among cancer patients is mostly advised to those with lung, laryngeal or oral cancer. National health surveys show that even general practitioners (GPs) do not advise and assist their patients in quitting smoking on regular basis (such advice is usually provided to only 40-50% of smoking patients). …”
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