The importance of basic and translational research in caring for children with malignant solid tumors in Latin America by María Belen Cancela, Milagros Dinardi, Rosario Aschero, Santiago Zugbi, Guillermo Chantada, Lorena Baroni, Paula Schaiquevich

“…The most commonly studied tumors were osteosarcomas, neuroblastomas and medulloblastomas; the most commonly studied areas were molecular analysis, tumor cell biology and biomarkers. …”
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RECONSTRUCTION WITH MODULAR ENDOPROSTHESIS AFTER PERIACETABULAR RESECTIONS IN PATIENS WITH PELVIC TUMORS. EARLY RESULTS. MULTICENTRAL R by V. U. Karpenko, V. A. Derzhavin, M. U. Shchupak, A. A. Zheravin, A. V. Buharov, A. V. Bondarev, G. S. Zhamgaryan

“…The histological types were as follows: 12 (52 %) chondrosarcomas, 4 (17 %) giant-cell tumors, 2 (8 %) osteosarcomas and 1 Ewing’s sarcoma, 1 malignant fibrous hystiocytoma, 1 synovial bone sarcoma, 1 solitary metastasis from renal cell and gastric carcinomas. …”
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MSH-5: índice para la detección oportuna de tumores malignos de rodilla by Gustavo Rivera-Saldívar, Rubén Torres-Gonzalez, Alejandra Cario-Méndez, Romeo Tecualt-Gómez, Rubén Amaya-Zepeda, Armando Alcántara-Corona, Silvestre Fuentes-Figueroa

“…El diagnóstico erróneo más frecuente es tendinitis, en el cual el 31% corresponden a osteosarcomas y el 21% a sarcomas de Ewing. Objetivo. …”
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2-APCAs, the Novel Microtubule Targeting Agents Active against Distinct Cancer Cell Lines by Sergei Boichuk, Aigul Galembikova, Firuza Bikinieva, Pavel Dunaev, Aida Aukhadieva, Kirill Syuzov, Svetlana Zykova, Nazim Igidov, Alexander Ksenofontov, Pavel Bocharov

“…Here, we report the discovery of 2-amino-pyrrole-carboxamides (2-APCAs), a novel class of MTA, which effectively inhibited the growth of the broad spectrum of cancer cell lines in vitro, including various types of breast, prostate, and non-small lung cancer (NSLC), soft tissue sarcomas (STS) (e.g., leio-, rhabdomyo-, and fibrosarcomas), osteosarcomas and gastrointestinal stromal tumors (GISTs). …”
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Clinicopathological and prognostic value of hypoxia-inducible factor-1α in patients with bone tumor: a systematic review and meta-analysis by Deqing Luo, Hongyue Ren, Wenjiao Zhang, Hang Xian, Kejian Lian, Hui Liu

“…Results A total of 28 studies including 1443 patients were included in this meta-analysis, which were involved in three different types of bone tumor including 3 chondrosarcomas, 2 giant cell tumors of bone, and 23 osteosarcomas. Our results showed that high expression levels of HIF-1α were associated with poorer OS (overall survival) (HR = 2.61, 95% CI 2.11–3.23, P <  0.001) and shorter DFS (disease-free survival) (HR = 2.02, 95% CI 1.41–2.89, P <  0.001) in bone tumor. …”
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A pilot study of multi-antigen stimulated cell therapy-I plus camrelizumab and apatinib in patients with advanced bone and soft-tissue sarcomas by Yan Zhou, Mei Li, Bing Zhang, Cheng Yang, Yaling Wang, Shuier Zheng, Lina Tang, Chenliang Zhou, Guowei Qian, Yujing Huang, Wenxi Yu, Hongtao Li, Yonggang Wang, Aina He, Zan Shen, Jianjun Zhang, Xiaoshuang Li, Qingcheng Yang, Haiyan Hu, Yang Yao

“…For the 13 patients with soft-tissue sarcomas, the ORR was 30.8%, DCR was 76.9%, and median PFS was 12.9 months; for the 6 patients with osteosarcomas, the ORR was 33.3%, the DCR was 50.0%, and median PFS was 5.7 months. …”
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Ambiente multimedial para la enseñanza de patologías quirúrgicas osteoarticulares by Santiago Andrés Audisio, Perla Araceli Torres, Pablo Vaquero, Edgardo Verna, Mariela Yanina Torres, Karina Natalia Santos, Laura Noelia Ocampo, Laura Domene, Cecilia Gonzalez, Carlos Alberto Salas, Clara Rial, Fernando Matías Cuadrelli Andreoli, Luisina Chapero, Mariela Anabel Cancina

“…El objetivo del proyecto es evaluar la utilidad del ambiente virtual como herramienta pedagógica Se emplearon especímenes de la colección de la cátedra entre los que se seleccionaron lesiones de osteítis productivas, osteosarcomas y osteoartritis. A cada especimen le fueron tomadas 20 fotografías digitales desde diversos ángulos con una cámara digital Kodak de 12 megapixeles en posición fija. …”
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