3′,4′-Dihydroxyflavonol Modulates the Cell Cycle in Cancer Cells: Implication as a Potential Combination Drug in Osteosarcoma by José Miguel P. Ferreira de Oliveira, Joana Filipa D. Almeida, Maria Martins, Carina Proença, Helena Oliveira, Eduarda Fernandes, Conceição Santos

“…New agents are demanded to increase the therapeutic options for osteosarcoma (OS). Although OS is the most common bone cancer in children and adolescents, it is considered a rare disorder. …”
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Cisplatin inhibits the proliferation of Saos-2 osteosarcoma cells via the miR-376c/TGFA pathway by Yuan Wang, Yichao Wu, Awei Cai, Chengxiao Ma, Shang Cai, Hao Wang, Yukang Que, Shenglin Xu, Tangbing Xu, Yong Hu

“…In this study, we investigated the mechanism underlying inhibitory effects of cisplatin on growth and proliferation of osteosarcoma cells. Osteosarcoma and normal skeletal muscle tissues were collected from 26 patients by biopsy. …”
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Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction by Junchao Zhu, Jinghong Yuan, Shahrzad Arya, Zhi Du, Xijuan Liu, Jingyu Jia

Subjects: “…osteosarcoma…”
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Prognostic analysis and clinical characteristics of osteosarcoma and Ewing sarcoma of the rib, sternum, and clavicle: a SEER-based study by Fangming He, Zhan Wang, Genlian Chen, Huanxin Lu

“…Objective Osteosarcoma and Ewing sarcoma of the rib, sternum, and clavicle are rare tumor entities, and their clinical features and treatment outcomes have been rarely reported. …”
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Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma by Weitang Guo, Xin Wang, Bing Lu, Jiaming Yu, Mingxian Xu, Renxuan Huang, Mingzhe Cheng, Meiling Yang, Wei Zhao, Changye Zou

“…Abstract Osteosarcoma (OS) is a common type of bone tumor for which there has been limited therapeutic progress over the past three decades. …”
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Targeting POLRMT by a first-in-class inhibitor IMT1 inhibits osteosarcoma cell growth in vitro and in vivo by Yang Kong, Xiangrong Li, Huanle Zhang, Bin Fu, Hua-Ye Jiang, Hui-Lin Yang, Jin Dai

“…Abstract Osteosarcoma (OS) is a highly aggressive form of bone cancer that predominantly affects adolescents and young adults. …”
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Cyclophosphamide Exerts an Anti-Metastatic Effect by Reducing the Expression of MMP-2 and -9 in Saos-2 Osteosarcoma Cells by Gülistan Sanem SARIBAŞ

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Limb sparing in a cat with a humeral osteosarcoma using a customised three-dimensional printed endoprosthesis by Anthony Malak, William CH Parr, Andrew S Levien, Rachel M Basa

“…A histopathological evaluation of the humerus confirmed a diagnosis of osteoblastic osteosarcoma. Limb-sparing surgery was planned with a custom-designed three-dimensional printed endoprosthesis. …”
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SGLT2 inhibitor activates the STING/IRF3/IFN-β pathway and induces immune infiltration in osteosarcoma by Wei Wu, Zhenhao Zhang, Doudou Jing, Xin Huang, Dianyun Ren, Zengwu Shao, Zhicai Zhang

“…However, the anticancer effect of SGLT2 inhibitors in osteosarcoma and the specific mechanism are still unclear. …”
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Sustained and Targeted Delivery of Self-Assembled Doxorubicin Nonapeptides Using pH-Responsive Hydrogels for Osteosarcoma Chemotherapy by Jie Zhu, Rui Gao, Zhongshi Wang, Zhiming Cheng, Zhonghua Xu, Zaiyang Liu, Yiqun Wu, Min Wang, Yuan Zhang

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Clinical model of pulmonary metastasis in patients with osteosarcoma: A new multiple machine learning-based risk prediction by Zhiping Su, Feihong Huang, Chunyue Yin, Yuezhao Yu, Chaojie Yu

“…Methods We collected data from 612 patients with osteosarcoma (OS), and 103 clinical indicators were collected. …”
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Characterization of IGF2R Molecular Expression in Canine Osteosarcoma as Part of a Novel Comparative Oncology Approach by Charles Boisclair, Ryan Dickinson, Sabeena Giri, Ekaterina Dadachova, Valerie MacDonald-Dickinson

Subjects: “…osteosarcoma…”
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Improving generalization of deep learning models for diagnostic pathology by increasing variability in training data: Experiments on osteosarcoma subtypes by Haiming Tang, Nanfei Sun, Steven Shen

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Prevalence of low bone mineral density and risk of fractures in osteosarcoma and Ewing’s sarcoma survivors: A scoping review by Keisuke Horiuchi, Ryuji Nemoto, Tsukasa Mizuno, Michiro Susa, Kazuhiro Chiba

Subjects: “…Osteosarcoma…”
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Identification of optimal reference genes for gene expression normalization in human osteosarcoma cell lines under proliferative conditions by Xiaoming Dong, Qiwei Yang, Zhenwu Du, Guizhen Zhang, Guizhen Zhang, Chuankai Shi, Xuyuan Qin, Yang Song

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3D-printing magnesium–polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures by Weilin Zhang, Wei Zhao, Qin Li, Duoyi Zhao, Junxing Qu, Ziyang Yuan, Zhihong Cheng, Xiaojuan Zhu, Xiuli Zhuang, Zhiyu Zhang

Subjects: “…Osteosarcoma…”
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Exploring the key genes and pathways of side population cells in human osteosarcoma using gene expression array analysis by Yi-Ming Ren, Yuan-Hui Duan, Yun-Bo Sun, Tao Yang, Wen-Jun Zhao, Dong-Liang Zhang, Zheng-Wei Tian, Meng-Qiang Tian

Subjects: “…Osteosarcoma…”
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Case Report: Giant cell-rich osteosarcoma of the cervical spine in the pediatric age. A rare entity to consider by Rosa M. Egea-Gámez, María Galán-Olleros, Alfonso González-Menocal, Rafael González-Díaz

Subjects: “…osteosarcoma - pathology…”
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Revealing the pharmacological effects of Remodelin against osteosarcoma based on network pharmacology, acRIP-seq and experimental validation by Jia Gao, Peili Xu, Feng Wang, Wenjie Zhang, Meipeng Min, Rafi Urba, Lei Fan

“…Abstract Osteosarcoma (OS) is the most common primary malignant tumor of bone. …”
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Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment by Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura

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