Showing 1,041 - 1,060 results of 2,473 for search '"osteosarcoma"', query time: 0.11s Refine Results
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    NUCKS1, a LINC00629-upregulated gene, facilitated osteosarcoma progression and metastasis by elevating asparagine synthesis by Shuo Zheng, Renchen Ji, Hongtao He, Na Li, Chuanchun Han, Jian Han, Xiaodong Li, Lu Zhang, Yuan Wang, Wenzhi Zhao

    Published 2023-08-01
    “…However, the biological functions and regulatory mechanism of NUCKS1 in osteosarcoma have not been fully understood. In this study, we reported that NUCKS1 was significantly increased in osteosarcoma. …”
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    Artificial intelligence reveals dysregulation of osteosarcoma and cuproptosis-related biomarkers, PDHA1, CDKN2A and neutrophils by Jie Jiang, Xinli Zhan, Jianxun Wei, Qie Fan, Haowen Li, Hao Li, Shuzhen Li, Yong Zhao, Guodong Yin, Lin Tang, Yongxiang Wu, Mindong Lan, Yijue Qin, Quan Guo, Weicheng Xu, Ling Lu, Yanwei Yang, Yitian Zhang, Haishun Qu

    Published 2023-03-01
    “…Abstract At present, the impact of cuproptosis-related genes in the study of osteosarcoma is largely unknown. Genome-wide data of osteosarcoma and controls were downloaded from 3 different databases, and specific diagnostic models associated with cuproptosis in osteosarcoma were constructed by support vector machines with artificial intelligence, random forest trees and LASSO regression. …”
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    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma by Renxian Wang, Dingding Wang, Xueshan Bai, Jianxun Guo, Songxia Xia, Yuning Cheng, Yani Gu, Qian Wang, Jingjun Nie, Dafu Chen, Weifeng Liu, Junbo Liang

    Published 2023-07-01
    “…Abstract Osteosarcoma is the most common malignant bone tumor, tending to be aggressive and recurrent. …”
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    Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. by Venugopal Thayanithy, ChangWon Park, Aaron L Sarver, Reena V Kartha, Derek M Korpela, Ashley J Graef, Clifford J Steer, Jaime F Modiano, Subbaya Subramanian

    Published 2012-01-01
    “…Downregulation of microRNAs (miRNAs) at the 14q32 locus stabilizes the expression of cMYC, thus significantly contributing to osteosarcoma (OS) pathobiology. Here, we show that downregulation of 14q32 miRNAs is epigenetically regulated. …”
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