Protocatechuic acid induces apoptosis in human osteosarcoma cells by regulating P13K/AKT/ROS pathway by Mei, Qiyuan, Chen, Xiaohu, Liu, Wei

“…It does, however, have an unknown cause on osteosarcoma cells. In this investigation, the underlying mechanism of the effect of PCA on osteosarcoma cells (MNNG or HOS) was investigated and established. …”
Get full text

Cisplatin-loaded graphene oxide/chitosan/hydroxyapatite composite as a promising tool for osteosarcoma-affected bone regeneration by Subbiah, Suresh Kumar, Murugan, Sumathra, Sadasivuni, Kishor Kumar, Rajan, Mariappan

“…This work focused on the cisplatin (CDDP)-loaded graphene oxide (GO)/hydroxyapatite (HAP)/chitosan (CS) composite for enhancing the growth of osteoblast cells and prevent the development of osteosarcoma cells. The prepared composites were characterized for the confirmation of composite formation using Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and X-ray diffraction techniques. …”
Get full text

Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines by Al-Ghashm, Abdulmlik

“…No previous study has been done to evaluate the effect of Tualang honey and O. stamineus on oral squamous cell carcinoma (OSCC) and human osteosarcoma (HOS). This study was aimed to verify the antiproliferative activity for several concentrations of Tualang honey, O. …”
Get full text

Five-year survival and prognostic factors of osteosarcoma patients in hospital University Sains Malaysia: An eleven year review by Wahidah, Tumijan

“…OBJECTIVES: The objectives of this study were to determine the five-year survival rate of osteosarcoma patients treated during the study period, to identify the prognostic factors that influence the risk of death of osteosarcoma patients and to establish a model that predicts the survival of osteosarcoma patients. …”
Get full text

Analysis of Intracellular Magnesium and Mineral Depositions during Osteogenic Commitment of 3D Cultured Saos2 Cells by Giovanna Picone, Concettina Cappadone, Alice Pasini, Joseph Lovecchio, Marilisa Cortesi, Giovanna Farruggia, Marco Lombardo, Alessandra Gianoncelli, Lucia Mancini, Menk Ralf H., Sandro Donato, Emanuele Giordano, Emil Malucelli, Stefano Iotti

Subjects: Get full text

Identification of an ADME-related gene for forecasting the prognosis and responding to immunotherapy in sarcomas by Jianlong Wang, Guowei Wang, Tianrui Hu, Hongyi Wang, Yong Zhou

Subjects: Get full text

Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy by Chia-Chieh Wu, Yi-Fu Huang, Chen-Pu Hsieh, Pin-Ju Chueh, Yao-Li Chen

Subjects: Get full text

RUNX Family as a Promising Biomarker and a Therapeutic Target in Bone Cancers: A Review on Its Molecular Mechanism(s) behind Tumorigenesis by Selvaraj Vimalraj, Saravanan Sekaran

Subjects: “…osteosarcoma…”
Get full text

Survival outcomes and surgical morbidity based on surgical approach to pulmonary metastasectomy in pediatric, adolescent and young adult patients with osteosarcoma by Christopher Kuo, Jemily Malvar, Yueh‐Yun Chi, Eugene S. Kim, Rachana Shah, Fariba Navid, James E. Stein, Leo Mascarenhas

Subjects: “…osteosarcoma…”
Get full text

Osteosarcoma with cell-cycle and fibroblast growth factor genomic alterations: case report of Molecular Tumor Board combination strategy resulting in long-term exceptional response by Hanna E. Persha, Shumei Kato, Pradip De, Jacob J. Adashek, Jason K. Sicklick, Vivek Subbiah, Razelle Kurzrock

Subjects: “…Osteosarcoma…”
Get full text

Transcriptomic Analysis of Canine Osteosarcoma from a Precision Medicine Perspective Reveals Limitations of Differential Gene Expression Studies by Rebecca L. Nance, Sara J. Cooper, Dmytro Starenki, Xu Wang, Brad Matz, Stephanie Lindley, Annette N. Smith, Ashley A. Smith, Noelle Bergman, Maninder Sandey, Jey Koehler, Payal Agarwal, Bruce F. Smith

Subjects: “…osteosarcoma…”
Get full text

Bioinformatics approach to identify the impacts of microgravity on the development of bone and joint diseases by Mst Rashida Akhtar, Md Nazrul Islam Mondal, Humayan Kabir Rana

Subjects: Get full text

Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway by Muhammad Nazirul Mubin, Aziz, Yazmin, Hussin, Nurul Fattin, Che Rahim, Noraini, Nordin, Nurul Elyani, Mohamad, Swee, Keong Yeap, Chean, Yeah Yong, Akhtar, Muhammad Nadeem, Mas Jaffri, Masarudin, Yoke, Kqueen Cheah, Nadiah, Abu, Noorjahan Banu, Alitheen

“…Osteosarcoma is one of the primary malignant bone tumors that confer low survival rates for patients even with intensive regime treatments. …”
Get full text

Retracted: LncRNA SNHG4 promotes osteosarcoma proliferation and migration by sponging miR‐377‐3p by Yi‐Feng Huang, Lei Lu, Hai‐Liang Shen, Xin‐Xiang Lu

Subjects: Get full text

Identification of TNFRSF21 as an inhibitory factor of osteosarcoma based on a necroptosis-related prognostic gene signature and molecular experiments by Xiang Li, Zhenqian Sun, Jinlong Ma, Miaomiao Yang, Hongxin Cao, Guangjun Jiao

Subjects: Get full text

Rabdomiólisis intraoperatoria en cirugía de resección de osteosarcoma de fémur: Reporte de caso y discusión by Luis Pablo Masco, Silvina Longo

Get full text

UHRF1 overexpression promotes osteosarcoma metastasis through altered exosome production and AMPK/SEMA3E suppression by Stephanie C. Wu, Ahhyun Kim, Yijun Gu, Daniel I. Martinez, Loredana Zocchi, Claire C. Chen, Jocelyne Lopez, Kelsey Salcido, Sarah Singh, Jie Wu, Ali Nael, Claudia A. Benavente

“…Here, we determined the role and regulatory mechanisms of UHRF1 in rendering osteosarcoma cells more aggressive. Higher UHRF1 expression correlated with malignancy in osteosarcoma cell lines, clinical samples, and genetically engineered mouse models. …”
Get full text

miR-328-3p mediates the anti-tumor effect in osteosarcoma via directly targeting MMP-16 by Jianhui Shi, Gang An, Ying Guan, Tianli Wei, Zhibin Peng, Min Liang, Yansong Wang

Subjects: Get full text

Mediating effect assessment of ifosfamide on limb salvage rate in osteosarcoma: A study from a single center in China by Yan Li, Yiwei Fu, Zhaohui Zhang, Zhuo Wang, Junqiang Yin, Jingnan Shen

Subjects: Get full text

CYR61 triggers osteosarcoma metastatic spreading via an IGF1Rβ-dependent EMT-like process by Nadia Habel, Bojana Stefanovska, Dimitri Carène, Ana Patiño-Garcia, Fernando Lecanda, Olivia Fromigué

“…Abstract Background Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. …”
Get full text