Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy by Chenyang Meng, Yun Yang, Wei Feng, Penglei Ma, Rui Bai

Subjects: “…Osteosarcoma…”
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Deep learning for differentiation of osteolytic osteosarcoma and giant cell tumor around the knee joint on radiographs: a multicenter study by Jingjing Shao, Hongxin Lin, Lei Ding, Bing Li, Danyang Xu, Yang Sun, Tianming Guan, Haiyang Dai, Ruihao Liu, Demao Deng, Bingsheng Huang, Shiting Feng, Xianfen Diao, Zhenhua Gao

“…Abstract Objectives To develop a deep learning (DL) model for differentiating between osteolytic osteosarcoma (OS) and giant cell tumor (GCT) on radiographs. …”
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Genomic nursing science revealed the prolyl 4-hydroxylase subunit alpha 2 as a significant biomarker involved in osteosarcoma by Hua-ping Chen, Xiao Han, Hui-ping Sun, Tao Xie, Xiao-liang Fan

Subjects: “…Osteosarcoma…”
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Lupeol inhibits osteosarcoma progression by up-regulation of HMGA2 via regulating miR-212-3p by Jinghua Zhong, Chunlei He, Fangtian Xu, Xianyun Xu, Lulin Liu, Mingjun Xu, Zheng Guo, Yili Wang, Jiahua Liao, Yonghong Li

“…Abstract Background Osteosarcoma (OS) is a common severe illness globally. …”
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Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis by Chien-Feng Huang, Yi-Hsien Hsieh, Shun-Fa Yang, Chao-Hung Kuo, Pei-Han Wang, Chung-Jung Liu, Renn-Chia Lin

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Pan-cancer analysis shows that IBSP is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including osteosarcoma by Boyu Pan, Xiaoyun Cheng, Xiaoyun Cheng, Wei Tan, Renfeng Liu, Xin Wu, Jinpeng He, Qizhi Fan, Yan Zhang, Jun Cheng, Jun Cheng, Youwen Deng

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Viable tumor cell density after neoadjuvant chemotherapy assessed using deep learning model reflects the prognosis of osteosarcoma by Kengo Kawaguchi, Kazuki Miyama, Makoto Endo, Ryoma Bise, Kenichi Kohashi, Takeshi Hirose, Akira Nabeshima, Toshifumi Fujiwara, Yoshihiro Matsumoto, Yoshinao Oda, Yasuharu Nakashima

“…Abstract Prognosis after neoadjuvant chemotherapy (NAC) for osteosarcoma is generally predicted using manual necrosis-rate assessments; however, necrosis rates obtained in these assessments are not reproducible and do not adequately reflect individual cell responses. …”
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Chondroblastic Osteosarcoma Associated with Previous Chronic Osteomyelitis Caused by <i>Serratia liquefaciens</i> in a German Shepherd Dog by Delia Franchini, Serena Paci, Stefano Ciccarelli, Carmela Valastro, Grazia Greco, Antonio Di Bello

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Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and SDF-1 by Fanlu Wang, Harald Schmidt, Dijana Pavleska, Thees Wermann, Andreas Seekamp, Sabine Fuchs

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CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588 by Zhizhong Liang, Yuxia Shi, Zhe Guan

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Retracted: Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway by Hang Lin, Yi Hao, Zhengxu Zhao, Yongjun Tong

“…However, the clinical significance and biological function of SIRT6 are not known for osteosarcoma (OS). Here, we report that SIRT6 was notably overexpressed in OS tissues compared with non‐cancerous specimens. …”
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How Do the Outcomes of Radiation-Associated Pelvic and Sacral Bone Sarcomas Compare to Primary Osteosarcomas following Surgical Resection? by Alexander L. Lazarides, Zachary D. C. Burke, Manit K. Gundavda, Rostislav Novak, Michelle Ghert, David A. Wilson, Peter S. Rose, Philip Wong, Anthony M. Griffin, Peter C. Ferguson, Jay S. Wunder, Matthew T. Houdek, Kim M. Tsoi

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Circ_WWC3 overexpression decelerates the progression of osteosarcoma by regulating miR-421/PDE7B axis by Liu Sihai, Zhang Jing, Zheng Ting, Mou Xiongneng, Xin Wenwei

“…Emerging evidence has shown that circular RNAs (circRNAs) are vital regulators in osteosarcoma (OS) progression. However, the effects of circ_WWC3 in OS have not been explored. …”
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CD44 expression is correlated with osteosarcoma cell progression and immune infiltration and affects the Wnt/β-catenin signaling pathway by Hairu Ji, Lingwei Kong, Yu Wang, Zhiping Hou, Wei Kong, Jiemin Qi, Yu Jin

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The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth by Sarah Morice, Mathilde Mullard, Regis Brion, Maryne Dupuy, Sarah Renault, Robel Tesfaye, Bénédicte Brounais-Le Royer, Benjamin Ory, Françoise Redini, Franck Verrecchia

Subjects: “…osteosarcoma…”
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CKM and TERT dual promoters drive CRISPR–dCas9 to specifically inhibit the malignant behavior of osteosarcoma cells by Yawei Hu, Hao Zhang, Zengfeng Guo, Jianhua Zhou, Wang Zhang, Ming Gong, Jiawen Wu

Subjects: “…Osteosarcoma…”
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Co-delivery of curcumin and si-STAT3 with a bioinspired tumor homing for polydopamine nanoparticles for synergistic osteosarcoma therapy by Kunzhe Wu, Zhongsheng Zhou, Te Liu, Chunkang Liu, Xupeng Mu, Jinlan Jiang

“…Results CPDA/siSTAT3@SCM NPs were successfully synthesized to deliver CUR and siRNA simultaneously, and they showed osteosarcoma-targeting ability. Furthermore, it showed high cellular uptake and excellent synergistic antitumor effects in vitro. …”
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Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis by Fengxiang Pang, Shouchang Ding, Nan Li, Zhipeng Li, Nannan Tian, Chuanjian Shi, Fengwei Zhang, Yongxin Mai, Jinfang Zhang, Junyan Wang

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Functional Characterization of Circadian Nuclear Receptors REV-ERBα and REV-ERBβ in Human Osteosarcoma Cell Cultures by Hana Cho, Ahee Yun, Joohee Kim, Eunjeong Park, Jong-Wha Jung, Sooyoung Chung, Gi Hoon Son

“…Therefore, this study aimed to identify the redundant and distinct roles of each isoform in controlling its target genes by comparing the transcriptome profiles of a panel of mutant U2OS human osteosarcoma cells in which either <i>NR1D1</i> or <i>NR1D2</i> was ablated. …”
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The combination of baseline neutrophil to lymphocyte ratio and dynamic changes during treatment can better predict the survival of osteosarcoma patients by Longqing Li, Ye Li, Minxun Lu, Yitian Wang, Zhuangzhuang Li, Xin Hu, Xuanhong He, Taojun Gong, Yi Luo, Yong Zhou, Li Min, Chongqi Tu

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