Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression by Cristina Fernández-Mendívil, Miguel A. Arreola, Lindsay A. Hohsfield, Kim N. Green, Manuela G. Lopez

Subjects: “…Heme oxygenase-1…”
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Heme Oxygenase-1 Is Upregulated during Differentiation of Keratinocytes but Its Expression Is Dispensable for Cornification of Murine Epidermis by Marta Surbek, Supawadee Sukseree, Attila Placido Sachslehner, Dragan Copic, Bahar Golabi, Ionela Mariana Nagelreiter, Erwin Tschachler, Leopold Eckhart

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Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis by Rachitha Singhabahu, Sujani M. Kodagoda Gamage, Vinod Gopalan

“…The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. …”
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Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors by Isha Sharma, Fei Deng, Yashpal S. Kanwar

Subjects: “…Myo-inositol oxygenase (MIOX)…”
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The Protective Effect of Heme Oxygenase-1 on Liver Injury Caused by DON-Induced Oxidative Stress and Cytotoxicity by Zitong Meng, Liangliang Wang, Yuxiao Liao, Zhao Peng, Dan Li, Xiaolei Zhou, Shuang Liu, Yanmei Li, Andreas K. Nüssler, Liegang Liu, Liping Hao, Wei Yang

“…The potentially harmful effect of DON given at doses comparable to the daily human consumption in target organs, especially the liver, which is the main detoxification organ of DON, is also still not fully understood. Otherwise, Heme Oxygenase-1 (HO-1) has also reduced cell damage under the DON condition according to our previous study. …”
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Spotlight on a New Heme Oxygenase Pathway: Testosterone-Induced Shifts in Cardiac Oxidant/Antioxidant Status by Renáta Szabó, Denise Börzsei, Krisztina Kupai, Alexandra Hoffmann, Rudolf Gesztelyi, Anikó Magyariné Berkó, Csaba Varga, Anikó Pósa

Subjects: “…heme oxygenase…”
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Labile Heme and Heme Oxygenase-1 Maintain Tumor-Permissive Niche for Endometriosis-Associated Ovarian Cancer by Jonathan L. Hecht, Monika Janikova, Reeham Choudhury, Fong Liu, Giacomo Canesin, Lubica Janovicova, Eva Csizmadia, Elisa M. Jorgensen, Katharine M. Esselen, Peter Celec, Kenneth D. Swanson, Barbara Wegiel

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Role of Heme-Oxygenase-1 in Biology of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells by Mateusz Jeż, Alicja Martyniak, Kalina Andrysiak, Olga Mucha, Krzysztof Szade, Alan Kania, Łukasz Chrobok, Katarzyna Palus-Chramiec, Anna M. Sanetra, Marian H. Lewandowski, Ewelina Pośpiech, Jacek Stępniewski, Józef Dulak

“…Heme oxygenase-1 (HO-1, encoded by <i>HMOX1</i>) is a cytoprotective enzyme degrading heme into CO, Fe²⁺, and biliverdin. …”
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Immunohistochemical localization of heme oxygenase-1 and bilirubin/biopyrrin of heme metabolites as antioxidants in human placenta with preeclampsia by Michiko Miya, Aikou Okamoto, Takashi Nikaido, Rie Tachimoto-Kawaguchi, Tadao Tanaka

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Heme oxygenase-1 and inflammation in experimental right ventricular failure on prolonged overcirculation-induced pulmonary hypertension. by Asmae Belhaj, Laurence Dewachter, François Kerbaul, Serge Brimioulle, Céline Dewachter, Robert Naeije, Benoît Rondelet

“…Heme oxygenase (HO)-1 is a stress response enzyme which presents with cardiovascular protective and anti-inflammatory properties. …”
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Identification of a c-type heme oxygenase and its function during acclimation of cyanobacteria to nitrogen fluctuations by Zhaoxing Ran, Zhenyu Du, Gengkai Miao, Mei Zheng, Ligang Luo, Xiaoqin Pang, Lanzhen Wei, Dezhi Li, Weimin Ma

“…The unknown protein is further identified as a c-type heme oxygenase (cHO) in tetrapyrrole biosynthetic pathway and catalyzes the opening of heme ring to form biliverdin IXα, which is required for phycobilin production and ensuing phycobiliprotein synthesis. …”
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In vitro characterization of a nitro-forming oxygenase involved in 3-(trans-2’-aminocyclopropyl)alanine biosynthesis by Linlin Pang, Weijing Niu, Yuwei Duan, Liujie Huo, Aiying Li, Jiequn Wu, Youming Zhang, Xiaoying Bian, Guannan Zhong

Subjects: “…Nitro-forming oxygenase…”
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Characterization of a novel P53 target gene, Heme Oxygenase (decycling) 1 (HMOX1) by Nam, Shin Yuen

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Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases by Brewitz, L, Nakashima, Y, Tumber, A, Salah, E, Schofield, CJ

“…2-Oxoglutarate (2OG) oxygenases have important roles in human biology and are validated medicinal chemistry targets. …”

Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus. by Bird, L, Ren, J, Zhang, J, Foxwell, N, Hawkins, A, Charles, I, Stammers, D

“…Prokaryotic genes related to the oxygenase domain of mammalian nitric oxide synthases (NOSs) have recently been identified. …”

Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk by Moore, R, Derry, S, McQuay, H

Comparative effects of cyclo-oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance. by Powell, K, Hosokawa, A, Bell, A, Sutak, M, Milne, B, Quirion, R, Jhamandas, K

Characterisation of caprine islet-related genes and enhancement of islet viability and function by heme oxygenase 1 gene by Vakhshiteh, Faezeh

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Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates by Matthew E Cockman, Kerstin Lippl, Ya-Min Tian, Hamish B Pegg, William D Figg Jnr, Martine I Abboud, Raphael Heilig, Roman Fischer, Johanna Myllyharju, Christopher J Schofield, Peter J Ratcliffe

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Genome-resolved analyses show an extensive diversification in key aerobic hydrocarbon-degrading enzymes across bacteria and archaea by Maryam Rezaei Somee, Mohammad Ali Amoozegar, Seyed Mohammad Mehdi Dastgheib, Mahmoud Shavandi, Leila Ghanbari Maman, Stefan Bertilsson, Maliheh Mehrshad

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