Median Nerve Neural Mobilization Adds No Additional Benefit When Combined with Cervical Lateral Glide in the Treatment of Neck Pain: A Randomized Clinical Trial by Daniel Martin-Vera, Josué Fernández-Carnero, David Rodríguez-Sanz, Cesar Calvo-Lobo, Ibai López-de-Uralde-Villanueva, Alberto Arribas-Romano, Pedro Martínez-Lozano, Daniel Pecos-Martín

“…Methods: A single-blinded randomized controlled clinical trial was carried out in a Pain Management Unit from a Hospital. A total sample of 72 patients with NP was recruited from a hospital. …”
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Transition to Virtual Care Services during COVID-19 at Canadian Pain Clinics: Survey and Future Recommendations by Victoria Borg Debono, Samuel Neumark, Norman Buckley, Ramesh Zacharias, Eleni Hapidou, Jennifer Anthonypillai, Susy Faria, Carrie-Lynn Meyer, Thomas Carter, Nadia Parker, Brenda Lau, Emmanuel Abreu, Scott Duggan, Etienne Bisson, Josie Pierre, Regina Visca, Patricia Poulin

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Reducing substance abuse in patients receiving prescription opioids for chronic non-cancer pain: a quality improvement and patient safety study in a primary care setting by Abdelrahman Ahmed, Emmanuel Akintoye, Neelima Thati

“…Interventions: (1) Rolling out of the chronic non-cancer pain management policy to clinic staff; (2) pain medication contracts with patients; (3) random urine drug screen (UDS) testing performed on patients during their clinic visits; 4) a didactics curriculum for internal medicine residents to highlight the key elements in utilizing and interpreting UDS results; (5) adding alerts to the electronic medical record that notifies clinic staff of discrepancy between patients’ prescribed medications and UDS findings, as well as for quick identification of patients who had violated a stipulation of the contract; (6) mandatory regular utilization of Michigan State’s online prescription monitoring records; and (7) employment of an on-site behavioral specialist for patients with mental illness or at risk of drug abuse. …”
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A systematic review to assess the use of psilocybin in the treatment of headaches by S. Bhanot, M. C. Q. Lin, S. Bains, A. Monroe, V. W. L. Tsang

“… Introduction Psilocybin is a naturally occurring psychedelic compound whose effects have been seen in studies for treatment of depression, anxiety and pain management. Given its structural similarities to 5-hydroxytryptamine, a monoamine controlling brain modulation of pain input, preliminary studies sought to test serotonergic interactions of psilocybin with headaches. …”
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What works to support carers of older people and older carers? an international evidence map of interventions and outcomes by Gemma Spiers, Michelle M.C. Tan, Jayne L Astbury, Alex Hall, Nisar Ahmed, Kate Lanyi, Oleta Williams, Fiona Beyer, Dawn Craig, Barbara Hanratty

“…Few studies evaluated interventions that focused on delivering financial information and advice, pain management, and physical skills training for carers. …”
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Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia: a systematic review and meta-analysis by Muhammad Hudaib, Hurais Malik, Syeda Javeria Zakir, Samra Rabbani, Dhanushan Gnanendran, Abdul Rehman Shah Syed, Noor Fatima Suri, Javeria Khan, Arham Iqbal, Nowal Hussain, Muhammad Abdullah, Satesh Kumar, Mahima Khatri, Giustino Varrassi

“…While propofol provides a faster onset of induction, ciprofol exhibits advantages in terms of pain management. Clinicians should consider these findings when selecting anesthetic agents, and tailoring choices to individual patient needs and clinical scenarios.…”
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Molecular Mechanisms Underlying the Retrieval and Extinction of Morphine Withdrawal-Associated Memories in the Basolateral Amygdala and Dentate Gyrus by Aurelio Franco-García, Francisco José Fernández-Gómez, Victoria Gómez-Murcia, Juana M. Hidalgo, M. Victoria Milanés, Cristina Núñez

“…Despite their indisputable efficacy for pain management, opiate prescriptions remain highly controversial partially due to their elevated addictive potential. …”
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The effect and safety of periarticular multimodal drug injection without morphine and epinephrine in anterior cruciate ligament reconstruction by Changhun Han, Yusuke Hashimoto, Sunao Nakagawa, Shinji Takahashi, Yohei Nishida, Shinya Yamasaki, Junsei Takigami, Hiroaki Nakamura

“…Background Periarticular multimodal drug injection (PMDI) is a safe and effective pain management technique after anterior cruciate ligament reconstruction (ACLR); however, adding morphine and epinephrine sometimes causes adverse effects. …”
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Biased versus Partial Agonism in the Search for Safer Opioid Analgesics by Joaquim Azevedo Neto, Anna Costanzini, Roberto De Giorgio, David G. Lambert, Chiara Ruzza, Girolamo Calò

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Pericapsular Nerves Group (PENG) Block in Children under Five Years of Age for Analgesia in Surgery for Hip Dysplasia: Case Report by Małgorzata Domagalska, Katarzyna Wieczorowska-Tobis, Tomasz Reysner, Alicja Geisler-Wojciechowska, Monika Grochowicka, Grzegorz Kowalski

“…Conclusions: This case series showed that the PENG block assured opioid-free pain management and provided adequate postoperative analgesia. …”
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Analgesic effectiveness of serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgery: a systematic review and updated meta-analysis of randomized co... by Jie Li, Xiaoyu Wang, Yinge Wang, Wenwu Zhang

“…Conclusion SAPB shows an excellent performance in postoperative pain management in patients undergoing VATS by reducing pains scores, postoperative opioid consumption and incidence of PONV. …”
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Chronic non malignant pain and nonsteroid antinflammatory drugs misuse: Nsaid misuse by Jovičić Jelena, Brkić Tatjana, Terzić Branka, Gvozdić Branka, Antonijević Vesna, Petrović Nataša D., Srećković Svetlana

“…Diclofenac 75 mg was added for severe pain management. Haematuria, eosinophylia, decreased creatinine clearance were consequences of NSAIDs toxic nephritis. …”
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A transmandibular lateral transsphenoidal navigated surgical approach to access a pituitary macroadenoma in a warmblood mare by Mathieu de Preux, Christina Precht, Julien Guevar, Claudia Graubner, Sebastian Thenhaus-Schnabel, Larissa Buser, Anton Lukes, Christoph Koch

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Erector Spinae Plane Block versus Paravertebral Block after Thoracic Surgery for Lung Cancer: A Propensity Score Study by Benjamin Durey, Zoubir Djerada, Fairuz Boujibar, Emmanuel Besnier, François Montagne, Jean-Marc Baste, Marie-Mélody Dusseaux, Vincent Compere, Thomas Clavier, Jean Selim

“…Introduction: The prevention of respiratory complications is a major issue after thoracic surgery for lung cancer, and requires adequate post-operative pain management. The erector spinae plane block (ESPB) may decrease post-operative pain. …”
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Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia by Xue Wang, Cong Lin, Siru Wu, Siru Wu, Tianshu Zhang, Tianshu Zhang, Yibo Wang, Yanfang Jiang, Xiaohui Wang, Xiaohui Wang, Xiaohui Wang

“…This study confirms that MD2 is a direct binding target of CBDV for the anti-neuroinflammatory effect and implies that CBDV has great translational potential in pain management.…”
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Trajectory of worst pain within the first two weeks following pelvic and sacral tumor surgery and long-term outcome: a pilot observational prospective cohort study by Qingfen Zhang, Yaqing Wu, Shenda Hong, Yi Feng

“…Abstract Background Pain management after pelvic and sacral tumor surgery is challenging and requires a multidisciplinary and multimodal approach. …”
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Vertebral Augmentation: Is It Time to Get Past the Pain? A Consensus Statement from the Sardinia Spine and Stroke Congress by Joshua A. Hirsch, Chiara Zini, Giovanni Carlo Anselmetti, Francisco Ardura, Douglas Beall, Matteo Bellini, Allan Brook, Alessandro Cianfoni, Olivier Clerk-Lamalice, Bassem Georgy, Gianluca Maestretti, Luigi Manfré, Mario Muto, Orlando Ortiz, Luca Saba, Alexis Kelekis, Dimitrios K. Filippiadis, Stefano Marcia, Salvatore Masala

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Pain Therapy and Regional Analgesia in Patients in the Intensive Care Unit: A Survey Study by Volkan Hancı, Şule Özbilgin, Serhan Yurtlu, Dilek Ömür Arça, Necati Gökmen, Atalay Arkan

“…Notably, the incidence of complications in regional analgesia methods was generally very low.Conclusion:The most commonly used drugs for pain management in intensive care units were opioids and NSAIDs. …”
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Therapeutic use of cannabinoids for the treatment of neurodegenerative disorders: a potential breakthrough by Danisha Kumar, Taimur Faheem Usmani, Moeez Tariq

“…Sherman et al. (2018) reported the association of cannabis administration with weight and pain management in AD patients. The adverse effects are typically well tolerated at the levels supplied, even though cannabis is linked to an increased risk of euphoria, sleepiness and psychosis (1). …”
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Virtual reality–guided mindfulness for chronic pain in cancer survivors: protocol for the virtual mind study—a single-group feasibility trial by Mohamad Baydoun, Zen Gajtani, Michaela Patton, Andrew McLennan, Stephen Cartwright, Linda E. Carlson

“…This study has been approved by the Health Research Ethics Board of Alberta Cancer Committee (HREBA.CC-20-0411).ConclusionsThis novel intervention provides a potential alternative treatment to pharmacological pain management. Results from this study may inform future larger VGRM trials for chronic CRP to help reduce suffering in people with cancer. …”
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