The effect of remifentanil on hemodynamic changes and muscle spasticity in patients undergoing total abdominal hysterectomy: A double-blind randomized clinical trial study by Hasan Zabetian, Sarina Malekzadeh, Navid Kalani, Farideh Mogharab, Mohammad Rahmanian

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Lidocaine infusion for the treatment of burn pain: A review of recent updates by Attia Attia, Assem Emam, Tarek Atta, Ahmed Harfoush, Mostafa Moataz, Ahmed Awny Basiouny, Assem Elshora, Aya Zidan

“…Therefore, we recommend further randomized, double blind, placebo-controlled trials to address the safety and efficacy of lidocaine infusion on pain management in burn patients. There is a controversy regarding dose of opioid consumption with intravenous lidocaine.…”
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Fumagillin Attenuates Spinal Angiogenesis, Neuroinflammation, and Pain in Neuropathic Rats after Chronic Constriction Injury by Zhi-Hong Wen, Shi-Ying Huang, Hsiao-Mei Kuo, Chao-Ting Chen, Nan-Fu Chen, Wu-Fu Chen, Kuan-Hao Tsui, Hsin-Tzu Liu, Chun-Sung Sung

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A Novel Rat Model to Study Postsurgical Pain After Joint Replacement Surgery by Aoyama N, Izumi M, Morimoto T, Wada H, Dan J, Kasai Y, Satake Y, Aso K, Ikeuchi M

“…Naoki Aoyama, Masashi Izumi, Toru Morimoto, Hiroyuki Wada, Junpei Dan, Yusuke Kasai, Yoshinori Satake, Koji Aso, Masahiko Ikeuchi Department of Orthopedic Surgery, Kochi Medical School, Kochi University, Nankoku, JapanCorrespondence: Masashi Izumi, Department of Orthopedic Surgery, Kochi Medical School, Kochi University, 185-1 Oko-cho Kohasu, Nankoku, 783-8505, Japan, Tel +81-88-880-2386, Fax +81-88-880-2388, Email izumim@kochi-u.ac.jpPurpose: The mechanisms underlying chronic postsurgical pain after joint replacement (JR) are complex, and it has been suggested that chronic postsurgical pain can develop as a result of inadequate acute pain management. Few studies have addressed acute pain after JR using specific animal models. …”
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Acupoint Catgut Embedding Diminishes Fibromyalgia Pain through TRPV1 in the Mouse Brain by Po-Chih Lai, Chia-Ming Yen, I-Han Hsiao, Yung-Hsiang Chen, Yi-Wen Lin

“…ACE is a novel acupuncture technique that provides convenience and continuous nerve stimulation that has been reported effective on pain management. Results: Our behavioral experiments showed similar levels of pain response among all groups before treatment. …”
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Mistreatment of women during childbirth and its influencing factors in public maternity hospitals in Tehran, Iran: a multi-stakeholder qualitative study by Marjan Mirzania, Elham Shakibazadeh, Meghan A. Bohren, Sedigheh Hantoushzadeh, Farah Babaey, Abdoljavad Khajavi, Abbas Rahimi Foroushani

“…Four themes were also identified as influencing factors: (1) individual-level factors (e.g., providers’ perception about women’s limited knowledge on childbirth process), (2) healthcare provider-level factors (e.g., provider stress and stressful working conditions); (3) hospital-level factors (e.g., staff shortages); and (4) national health system-level factors (e.g., lack of access to pain management during labour and childbirth). Conclusions Our study showed that women experienced various forms of mistreatment during labour and childbirth. …”
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Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study by Mateusz Szmit, Siddarth Agrawal, Waldemar Goździk, Andrzej Kübler, Anil Agrawal, Piotr Pruchnicki, Marta Woźniak, Matylda Nowak, Bartłomiej Bartoszewicz, Jerzy Rudnicki

“…Given the rising rate of opioid-related adverse drug events during postsurgical pain management, a nonpharmacologic therapy that could decrease analgesic medication requirements would be of immense value. …”
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Efficacy of preemptive intercostal nerve block on recovery in patients undergoing video-assisted thoracic lobectomy by Shaojuan Chen, Zhihua Guo, Xin Wei, Zhenzhu Chen, Na Liu, Weiqiang Yin, Lan Lan

“…Conclusions Pre- ICNB is equally efficacious in perioperative pain management as post-ICNB, and pre-ICNB significantly reduces intra-operative opioid consumption, providing faster recovery in PACU. …”
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Efficacy and Safety of Ketamine Versus Opiates in the Treatment of Patients with Renal Colic: A Systematic Review and Meta-analysis by Dongxu Zhang, Pu Liang, Bowen Xia, Xin Zhang, Xiaopeng Hu

“…Abstract Introduction Renal colic is one of the most common urological emergencies, and is usually caused by ureteral colic spasms. Pain management in renal colic remains the central focus of emergency treatment. …”
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Effects of different acupuncture manipulations on protein expression in the parietal cortex of spontaneously hypertensive rats by Jiaojuan Wu, Tianxiao Zeng, Jingrong Liang, Xudong Zhang, Qi Xie, Taotao Lv, Pui Yee Wong, Zhi Ji, Qingguo Liu

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A Protocol for a Single-Centered, Pragmatic, Randomized, Controlled, Parallel Trial Comparing Comprehensive Nonsurgical Therapy Options for Individuals with Lumbar Spinal Stenosis by Sun Y, An Y, Fan X, Liu C, Li D, Lei Y, Weng Z, Gong Y, Wang X, Yu C

“…Ya’nan Sun,1,* Yi An,2,* Xiran Fan,2 Changxin Liu,3 Duoduo Li,3 Yuan Lei,3 Zhiwen Weng,3 Yuanyuan Gong,3 Xiyou Wang,3 Changhe Yu3 1Traditional Chinese Medicine Department, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China; 2First Clinical College, Beijing University of Chinese Medicine Affiliated Dongzhimen Hospital, Beijing, People’s Republic of China; 3Tuina and Pain Management Department, Beijing University of Chinese Medicine Affiliated Dongzhimen Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiyou Wang; Changhe Yu, Email dwxy658@163.com; yakno2@163.comAim: Lumbar spinal stenosis (LSS) is a long-term degenerative disease. …”
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Survey of Surgeon-reported Postoperative Protocols for Deep Inferior Epigastric Perforator Flap in Breast Reconstruction by Sthefano Araya, MD, Madison Hackley, BS, Grace M. Amadio, BS, Mengying Deng, MS, Civanni Moss, BSN, RN, Eliann Reinhardt, BA, BM, Adam Walchak, MD, Michael G. Tecce, MD, Sameer A. Patel, MD, FACS

“…Such protocols have the potential to reduce both the length of hospital stays and overall care costs all while ensuring optimal pain management and vigilant flap monitoring.…”
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Pain reduction in fibromyalgia syndrome through pairing transcranial direct current stimulation and mindfulness meditation: A randomized, double-blinded, sham-controlled pilot clin... by Perianen Ramasawmy, Sarah Khalid, Frank Petzke, Andrea Antal

“…The combined treatment was well tolerated among participants, with no serious adverse effects.ConclusionThis study was the first to pair these two effective non-pharmacological therapies for pain management in FMS. In the light of an underpowered sample size, repetitive anodal tDCS combined with MM did not improve pain or FMS-associated symptoms. …”
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Nomogram for predicting severe abdominal pain after initial conventional transarterial chemoembolisation for hepatocellular carcinoma: a retrospective study by Huixia Qin, Xuhua Xiao, Houxiang Ya, Jinhai Li, Fugang Liang, Haiqing Jin, Lianghuan Liao, Yaohua Li, Jiahui Qin, Jue Yu, Jing Gu, Chunmei Zhou, Ming Jin, Ying Miao, Shuqun Li

“…The nomogram model can provide an accurate prediction of severe abdominal pain in patients with HCC after first cTACE, aiding in the personalization of pain management and providing novel insights into hospital nursing.…”
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An implantable device for localized drug delivery and sensing by Daniel, Karen D

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Increasing utilization of strong opioid analgesics in a UK primary care population by Zin, Che Suraya, Chen, Li-Chia, Knaggs, Roger D

“…Data were obtained from patients prescribed a strong opioid-containing drug (buprenorphine, fentanyl, morphine and oxycodone) for pain management from 1st January 2000 to 31st December 2010 by using specific product codes. …”
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Building health system capacity through medical education: a targeted needs assessment to guide development of a structured internal medicine curriculum for medical interns in Bots... by Peluso, MJ, Tapela, N, Langeveldt, J, Williams, ME, Mochankana, K, Motseosi, K, Ricci, B, Rodman, A, Haverkamp, C, Haverkamp, M, Maoto, R, Luckett, R, Prozesky, D, Nkomazana, O, Barak, T

“…Interns felt they had adequate exposure to content such as HIV and tuberculosis, but inadequate exposure to areas including medical emergencies, non-communicable diseases, pain management, procedural skills, X-ray and EKG interpretation, disclosing medical information, and identifying career goals. …”

Carbamazepine for acute and chronic pain in adults. by Wiffen, P, Derry, S, Moore, R, McQuay, H

“…OBJECTIVES: Evaluation of analgesic efficacy and adverse effects of carbamazepine for acute and chronic pain management (except headaches). SEARCH STRATEGY: Randomised controlled trials (RCTs) of carbamazepine in acute, chronic or cancer pain were identified, searching MEDLINE, EMBASE, SIGLE and Cochrane CENTRAL to June 2010, reference lists of retrieved papers, and reviews. …”

Chronic fatigue syndromes: real illnesses that people can recover from by Tomas Nordheim Alme, Anna Andreasson, Tarjei Tørre Asprusten, Anne Karen Bakken, Michael BJ Beadsworth, Birgitte Boye, Per Alf Brodal, Elias Myrstad Brodwall, Kjetil Gundro Brurberg, Ingrid Bugge, Trudie Chalder, Reidar Due, Hege Randi Eriksen, Per Klausen Fink, Signe Agnes Flottorp, Egil Andreas Fors, Bård Fossli Jensen, Hans Petter Fundingsrud, Paul Garner, Lise Beier Havdal, Helene Helgeland, Henrik Børsting Jacobsen, Georg Espolin Johnson, Martin Jonsjö, Hans Knoop, Live Landmark, Gunvor Launes, Mats Lekander, Hannah Linnros, Elin Lindsäter, Helena Liira, Lina Linnestad, Jon Håvard Loge, Peter Solvoll Lyby, Sadaf Malik, Ulrik Fredrik Malt, Trygve Moe, Anna-Karin Norlin, Maria Pedersen, Siv Elin Pignatiello, Charlotte Ulrikka Rask, Silje Endresen Reme, Gisle Roksund, Markku Sainio, Michael Sharpe, Ruth Foseide Thorkildsen, Betty van Roy, Per Olav Vandvik, Henrik Vogt, Hedda Bratholm Wyller, Vegard Bruun Bratholm Wyller

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Tracheostomy Timing and Outcome in Severe COVID-19: The WeanTrach Multicenter Study by Denise Battaglini, Francesco Missale, Irene Schiavetti, Marta Filauro, Francesca Iannuzzi, Alessandro Ascoli, Alberto Bertazzoli, Federico Pascucci, Salvatore Grasso, Francesco Murgolo, Simone Binda, Davide Maraggia, Giorgia Montrucchio, Gabriele Sales, Giuseppe Pascarella, Felice Eugenio Agrò, Gaia Faccio, Sandra Ferraris, Savino Spadaro, Giulia Falò, Nadia Mereto, Alessandro Uva, Jessica Giuseppina Maugeri, Bellissima Agrippino, Maria Vargas, Giuseppe Servillo, Chiara Robba, Lorenzo Ball, Francesco Mora, Alessio Signori, Antoni Torres, Daniele Roberto Giacobbe, Antonio Vena, Matteo Bassetti, Giorgio Peretti, Patricia R. M. Rocco, Paolo Pelosi

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