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4061
Effects of pharmacogenetic profiles on pediatric pain relief and adverse events with ibuprofen and oxycodone
Published 2023-12-01“…This pragmatic prospective, observational cohort included children aged 4 to 16 years who were seen in a pediatric emergency department with an acute fracture and prescribed ibuprofen or oxycodone for at-home pain management. Saliva samples were obtained for genotyping of allelic variants, and daily telephone follow-up was conducted for 3 days. …”
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4062
Long-term and serious harms of medical cannabis and cannabinoids for chronic pain: a systematic review of non-randomised studies
Published 2022-08-01“…We found insufficient evidence addressing the harms of medical cannabis compared with other pain management options, such as opioids.Conclusions There is very low certainty evidence that adverse events are common among people living with chronic pain who use medical cannabis or cannabinoids, but that few patients experience serious adverse events.…”
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4063
Five healthcare trajectories in the year before suicide and what they tell us about opportunities for prevention: a population-level case series studyResearch in context
Published 2023-09-01“…Trajectories B and D might benefit from opioid dispensing limits and access to psychological pain management. Trajectory C had high mental health medicine use, indicating that the time that medicines are prescribed or dispensed are important touchpoints. …”
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4064
Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies
Published 2023-08-01“…William D Chey,1 Darren M Brenner,2 Brooks D Cash,3 Martin Hale,4 Jeremy Adler,5 Mansi S Jamindar,6 Carol B Rockett,6 June S Almenoff,6 Enoch Bortey,7 Jeffrey Gudin8 1Department of Internal Medicine, Division of Gastroenterology and Hepatology, Michigan Medicine, Ann Arbor, MI, USA; 2Departments of Medicine and Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; 3Division of Gastroenterology, Hepatology, and Nutrition at the University of Texas Health Science Center at Houston, Houston, TX, USA; 4Gold Coast Research, L.L.C, Miami, FL, USA; 5Pacific Pain Medicine Consultants, Encinitas, CA, USA; 6Medical Affairs, RedHill Biopharma, Inc, Raleigh, NC, USA; 7Pharmaceutical Development Strategies, L.L.C, Chapel Hill, NC, USA; 8Department of Anesthesiology and Pain Management, University of Miami, Miami, FL, USACorrespondence: June S Almenoff, Email jalmenoff@redhillus.comObjective: This study evaluates the onset, magnitude, and consistency of improvement of opioid-induced constipation (OIC) symptoms with naloxegol treatment.Methods: This was a pooled analysis of two Phase 3, double-blind, randomized, placebo-controlled studies (KODIAC-04/05, NCT01309841/NCT01323790) in patients with chronic non-cancer pain and OIC treated with naloxegol 25mg or 12.5mg daily. …”
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4065
Applying a knowledge translation framework for triaging low back pain and radicular pain at an emergency department: an iterative process within an uncontrolled before-and-after de...
Published 2022-11-01“…Although evidence-based guidelines for LBP and radicular pain management exist, a protocol for use at the ED in the Belgian University Hospitals Leuven was not available, resulting in high practice variation. …”
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4066
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4067
Protocol for double-blind RCT of acupuncture for vulvodynia
Published 2022-12-01“…Conclusion: This study is responsive to the need for efficacious pain management for women with vulvodynia.ClinicalTrials.gov Identifier: NCT03364127.…”
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4068
The Effectiveness of Intravenous lidocaine in Burn Pain Relief: A Randomized Double-Blind Controlled Trial
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4069
Tafalgin is a Russian innovative tetrapeptide pharmaceutical for subcutaneous injection: review of the results of phase I and II clinical trials
Published 2022-08-01“…Tafalgin is characterized by fast absorption after subcutaneous administration (less than 30 minutes) which allows for fast clinical effect and absence of accumulation in the body. use of this pharmaceutical in patients with cancer allowed to maintain appropriate pain management achieved earlier through intramuscular morphine administration in 100 % of cases. …”
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4071
A remote group-mediated daylong physical activity intervention for older adults with chronic pain: Results of the MORPH-II randomized pilot trial
Published 2022-11-01“…Chronic pain is a debilitating condition that affects many older adults who often have limited access to non-pharmacological pain management strategies. One potentially effective and novel lifestyle medicine for chronic pain involves increasing physical activity through frequent movement across the day, thereby also decreasing the presence of extended sedentary bouts. …”
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4072
Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study
Published 2019-06-01“…All patients underwent a fast-track program including nutrition, blood, and pain management; VTE prophylaxis; early mobilization; and early intake. …”
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4073
Botulinum Toxin-A Injection in Chronic Pelvic Pain Syndrome Treatment: A Systematic Review and Pooled Meta-Analysis
Published 2022-01-01“…Introduction: Pain management of patients with chronic pelvic pain syndrome (CPPS) is challenging, because pain is often refractory to conventional treatments. …”
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4074
Analgesic Effect of Intraoperative Intravenous S(+)-Ketamine During Total Knee Arthroplasty Surgery: Study Protocol for a Randomized Controlled Clinical Trial
Published 2023-12-01“…ObjectiveEffective multimodal pain management in the early postoperative period is essential for anesthesiologists. …”
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4075
Acupuncture versus massage for pain in patients living with advanced cancer: a protocol for the IMPACT randomised clinical trial
Published 2022-09-01“…Clinical guidelines recommend non-pharmacological interventions, including acupuncture and massage, for pain management in adult patients with cancer in adjunct to conventional care. …”
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Continuous wound infusion catheter as part of a multimodal analgesia regimen for post-Caesarean delivery pain: a quality improvement impact study
Published 2024-03-01“…Conclusions: The addition of continuous wound infusion catheters to a multimodal analgesia regimen for post-Caesarean delivery pain management demonstrated minimal clinically significant analgesic benefits. …”
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4078
A rare case of successful pain control in a prostate cancer patient with bone metastasis undergoing hemodialysis by measuring the serum oxycodone level and using an activity tracke...
Published 2022-09-01“…Case Presentation: A 72-year-old male, with a history of hemodialysis induced by diabetic nephropathy for 16 years and prostate cancer for three years, was diagnosed with metastasis in his 12th thoracic and 2nd lumbar vertebrae, and treated with analgesic pain management (oxycodone, acetaminophen, and pregabalin) and radiotherapy. …”
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4079
Epidemiological Factors Associated with Prescription of Opioids for Chronic Non-Cancer Pain in Adults: A Country-Wide, Registry-Based Study in Denmark Spans 2004–2018
Published 2023-02-01“…Carrinna Aviaja Hansen,1– 4 Martin Thomsen Ernst,4,5 Christopher Dyer Smith,4 Bo Abrahamsen4,6 1Department of Orthopedic Surgery, Zealand University Hospital, University of Copenhagen, Koege, Denmark; 2Department of Regional Health Research, University of Southern Denmark, Odense, Denmark; 3Department of Anesthesia, Respiratory Support and Pain Management, the Neuroscience Centre, Rigshospitalet, Glostrup, University of Copenhagen, Copenhagen, Denmark; 4Odense Patient Data Explorative Network, University of Southern Denmark, Odense, Denmark; 5Department of Public Health, University of Southern Denmark, Odense, Denmark; 6Department of Medicine, Holbaek Hospital, Holbaek, DenmarkCorrespondence: Carrinna Aviaja Hansen, Zealand University Hospital, University of Copenhagen, Department of Orthopedic Surgery, Lykkebaekvej 1, Koege, 4600, Denmark, Tel +45 9357 6524, Email carrh@regionsjaelland.dkPurpose: Denmark has a high consumption of prescribed opioids, and many citizens with chronic non-cancer pain (CNCP). …”
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4080
TEleRehabilitation Nepal (TERN) for People With Spinal Cord Injury and Acquired Brain Injury: A Feasibility Study
Published 2022-10-01“…The telerehabilitation programme facilitated the delivery of support around multiple aspects of rehabilitation care, such as spasticity treatments and pain management. Outcome measures indicated a significant improvement in functional independence ( P < .001), depression, anxiety and stress ( P < .001) and quality of life ( P < .001). …”
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