Pain, comorbidities, and clinical decision-making: conceptualization, development, and pilot testing of the Pain in Aging, Educational Assessment of Need instrument by Bernadette C. Siaton, Bernadette C. Siaton, Beth B. Hogans, Beth B. Hogans, Laura A. Frey-Law, Lana M. Brown, Christopher M. Herndon, Christopher M. Herndon, Luis F. Buenaver

“…To address gaps in clinical training and geriatric pain management, we established the Pain in Aging—Educational Assessment of Need (PAEAN) project to appraise the impacts of medical and mental health conditions on clinical decision-making regarding older adults with pain. …”
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The Association between Sleep and Chronic Spinal Pain: A Systematic Review from the Last Decade by Eveline Van Looveren, Thomas Bilterys, Wouter Munneke, Barbara Cagnie, Kelly Ickmans, Olivier Mairesse, Anneleen Malfliet, Liesbet De Baets, Jo Nijs, Dorien Goubert, Lieven Danneels, Maarten Moens, Mira Meeus

“…Addressing frequently reported sleep problems in chronic spinal pain patients therefore appears to be a necessary complement to pain management to achieve optimal treatment outcomes.…”
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Testing implementation facilitation of a primary care-based collaborative care clinical program using a hybrid type III interrupted time series design: a study protocol by Amanda M. Midboe, Steve Martino, Sarah L. Krein, Joseph W. Frank, Jacob T. Painter, Michael Chandler, Allison Schroeder, Brenda T. Fenton, Lara Troszak, Taryn Erhardt, Robert D. Kerns, William C. Becker

“…Participants include pharmacists and allied staff involved in the delivery of clinical pain management services as well as patients. Eligible patients are prescribed either an outpatient opioid prescription greater than or equal to 90 mg morphine equivalent daily dose or a combination opioid-benzodiazepine regimen. …”
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A Retrospective Comparison of Three Patient-Controlled Analgesic Strategies: Intravenous Opioid Analgesia Plus Abdominal Wall Nerve Blocks versus Epidural Analgesia versus Intraven... by Hsin-I Tsai, Yu-Chieh Lu, Chih-Wen Zheng, Ming-Chin Yu, An-Hsun Chou, Cheng-Han Lee, Hao-Wei Kou, Jr-Rung Lin, Yu-Hua Lai, Li-Ling Chang, Chao-Wei Lee

“…<b>Conclusions</b>: For postoperative pain management, it is expected that the TEA group required the least amount of opioid; however, IV-PCA + NBs and TEA demonstrated comparable postoperative outcomes, namely, the time to remove nasogastric tube/urinary catheter, to start the diet, and the length of hospital stay. …”
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Factors Associated with Increased Analgesic Use in German Women with Endometriosis during the COVID-19 Pandemic by Roxana Schwab, Kathrin Stewen, Tanja Kottmann, Mona W. Schmidt, Katharina Anic, Susanne Theis, Bashar Haj Hamoud, Tania Elger, Walburgis Brenner, Annette Hasenburg

“…(1) Background: Endometriosis is a frequent chronic pain condition in women of fertile age. Pain management with analgesics is frequently used by women with endometriosis. …”
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Analgesic efficacy of ultrasound-guided transversus abdominis plane block in dogs undergoing ovariectomy by Jéssica Sperandio Cavaco, Pablo Ezequiel Otero, Aline Magalhães Ambrósio, Ieda Cristina Boni Neves, Felipe Montanheiro Perencin, Marco Aurélio Amador Pereira, Julia Maria Matera, Denise Tabacchi Fantoni

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Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China by Ma K, Cheng Z, Jiang H, Lin Z, Liu C, Liu X, Lu L, Lu Y, Tao W, Wang S, Yang X, Yi Q, Zhang X, Zhang Y, Liu Y

“…Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, People’s Republic of China; 15Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ke Ma, Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University school of medicine, Shanghai, 200092, People’s Republic of China, Tel +86133618792160, Email marke72@163.com Yanqing Liu, Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People’s Republic of China, Tel +8618601203409, Email lyqttyy@126.comAbstract: Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. …”
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Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study by Chongjie Yao, Yuchen Zhang, Ping Lu, Bin Xiao, Pingping Sun, Jiming Tao, Yanbin Cheng, Lingjun Kong, Dongsheng Xu, Min Fang

“…Conclusions Our results enhance the understanding of the complex interplay between pain and mental health and highlight the importance of a holistic approach to pain management that addresses both physical and psychological factors.…”
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Systematic literature review of the impact of psychiatric pharmacists by Jessica L. Ho, PharmD, BCPP, BCPS, Jenna Roberts, PharmD, BCPP, Gregory H. Payne, MBA, CAE, Dorothy N. Holzum, PharmD, BCPP, BCPS, Hannah Wilkoff, PharmD, BCPP, Tran Tran, PharmD, BCPS, Carla D. Cobb, PharmD, BCPP, Tera D. Moore, PharmD, BCACP, Kelly C. Lee, PharmD, MAS, BCPP

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The Quantum Tunneling of Ions Model Can Explain the Pathophysiology of Tinnitus by Baeth M Al-Rawashdeh, Abdallah Barjas Qaswal, Aiman Suleiman, Fuad Mohammed Zayed, S. M. Al-Rawashdeh, Mohamed Tawalbeh, Lubna Khreesha, Ayham Alzubaidi, Enas Al-Zubidi, Zuhir Ghala, Ahmad Almasri, Mohammed Yasein, Khaled Ojjoh, Ahmad Alraiqib, Mohammad Iswaid, Murad Emar, Shahed Haimour, Ala’ Saifan, Zaid Mahameed

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Investigation of preclinical pharmacokinetics of N-demethylsinomenine, a potential novel analgesic candidate, using an UPLC-MS/MS quantification method by Lulu Yu, Xunjia Qian, Yiheng Feng, Yujian Yin, Xiao-Dan Zhang, Qianqian Wei, Liyun Wang, Weiwei Rong, Weiwei Rong, Jie-Jia Li, Jun-Xu Li, Qing Zhu, Qing Zhu

“…N- Demethylsinomenine (NDSM), the in vivo demethylated metabolite of sinomenine, has exhibited antinociceptive efficacy against various pain models and may become a novel drug candidate for pain management. However, no reported analytical method for quantification of N- Demethylsinomenine in a biological matrix is currently available, and the pharmacokinetic properties of N- Demethylsinomenine are unknown. …”
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Virtual reality hypnosis diminishes experimental cold pain and alters autonomic responses by Claire Terzulli, Claire Terzulli, Chloé Chauvin, Chloé Chauvin, Cédric Champagnol Di-Liberti, Sylvain Faisan, Laurent Goffin, Coralie Gianesini, Denis Graff, Denis Graff, André Dufour, Edouard Laroche, Eric Salvat, Pierrick Poisbeau

“…Further studies are expected to determine more precisely to whom it will be the most useful to offer tailored, non-pharmacological pain management solutions to patients.…”
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Accuracy Evaluation Trial of Mixed Reality-Guided Spinal Puncture Technology by Wu J, Gao L, Shi Q, Qin C, Xu K, Jiang Z, Zhang X, Li M, Qiu J, Gu W

“…Jiajun Wu,1,2,&ast; Lei Gao,1,2,&ast; Qiao Shi,3 Chunhui Qin,4 Kai Xu,1,2 Zhaoshun Jiang,1,2 Xixue Zhang,1,2 Ming Li,5 Jianjian Qiu,6,&ast; Weidong Gu1,2,&ast; 1Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicine, Shanghai, 200040, People’s Republic of China; 3Department of Anesthesiology, International Peace Maternity and Child Health Hospital of China, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, People’s Republic of China; 4Department of Pain Management, Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, People’s Republic of China; 5Department of Radiology, Huadong Hospital affiliated to Fudan University, Shanghai, 200040, People’s Republic of China; 6Department of Radiation Oncology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Weidong Gu; Jianjian Qiu, Email hdmz0800@163.com; qiujianjian@fudan.edu.cnPurpose: To evaluate the accuracy of mixed reality (MR)-guided visualization technology for spinal puncture (MRsp).Methods: MRsp involved the following three steps: 1. …”
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Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates by Amanda Klein, Hans Jürgen Solinski, Nathalie M Malewicz, Hada Fong-ha Ieong, Elizabeth I Sypek, Steven G Shimada, Timothy V Hartke, Matthew Wooten, Gang Wu, Xinzhong Dong, Mark A Hoon, Robert H LaMotte, Matthias Ringkamp

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Effects of cardamonin alleviate hyperalgesia and allodynia with possible involvement of monoaminergic pathways in chronic constriction injury-induced neuropathic pain mice model by Kaswan, Nur Khalisah

“…In conclusion, our findings demonstrated that monoaminergic pathways were involved in mediating the antineuropathic effect of cardamonin in CCI induced neuropathic pain model and can be a new therapeutic approach for neuropathic pain management.…”
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The impact of epidural analgesia on delivery mode in Robson class 1 women: a retrospective cohort studyAJOG MFM at a Glance by Fedora Ambrosetti, MD, Giovanni Grandi, MD, Elisabetta Petrella, MD, Veronica Sampogna, MD, Lara Donno, MD, Laura Rinaldi, MD, Anna Maria Ghirardini, MD, Fabio Facchinetti, MD

“…BACKGROUND: The use of epidural analgesia represents the gold standard for pain management during labor, but the influence of the use of epidural analgesia on delivery mode is not fully understood. …”
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Postoperative Analgesic Efficacy of Transverse Abdominis Plane Block versus Port Site Local Infiltration in Laparoscopic Gynaecological Surgeries-A Randomised Clinical Trial by MS Anusha, K Udaya Bhaskar, Jaganath, T Dharani Priya, Mohan Koyee

“…Non Steroidal Anti-Inflammatory Drugs (NSAIDs) and opioids are the most commonly used drugs in pain management. Transverse Abdominis Plane (TAP) block is a regional analgesic technique, which provides analgesia of the anterolateral abdominal wall and hence can be used to provide analgesia for caesarean section, hernia repairs, hysterectomies, cholecystectomy. …”
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Scheduled and Breakthrough Opioid Use for Cancer Pain in an Inpatient Setting at a Tertiary Cancer Hospital by Aline Rozman de Moraes, Elif Erdogan, Ahsan Azhar, Suresh K. Reddy, Zhanni Lu, Joshua A. Geller, David Mill Graves, Michal J. Kubiak, Janet L. Williams, Jimin Wu, Eduardo Bruera, Sriram Yennurajalingam

“…<b>Background</b>: Our aim was to examine the frequency and prescription pattern of breakthrough (BTO) and scheduled (SCH) opioids and their ratio (BTO/SCH ratio) of use, prior to and after referral to an inpatient supportive care consult (SCC) for cancer pain management (CPM). <b>Methods and Materials</b>: Patients admitted at the MD Anderson Cancer Center and referred to a SCC were retrospectively reviewed. …”
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Prevalence and Risk Factors for Iatrogenic Opioid Withdrawal in Medical Critical Care Patients by Marlena A. Fox, PharmD, BCPS, BCCCP, Chancey Carothers, PharmD, BCCCP, Katie K. Dircksen, PharmD, BCCCP, Kara L. Birrer, PharmD, BCPS, Min J. Choi, PharmD, Satyanarayana R. Mukkera, MD

“…Opioids are the mainstay of pain management and sedation in critically ill patients, which can lead to the development of physiologic tolerance and dependency. …”
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Comparing the clinical and cost-effectiveness of remote (telehealth and online) cognitive behavioral therapy-based treatments for high-impact chronic pain relative to usual care: s... by Meghan Mayhew, Benjamin H. Balderson, Andrea J. Cook, John F. Dickerson, Charles R. Elder, Alison J. Firemark, Irina V. Haller, Morgan Justice, Francis J. Keefe, Carmit K. McMullen, Maureen C. O’Keeffe-Rosetti, Ashli A. Owen-Smith, Christine Rini, Jennifer L. Schneider, Michael Von Korff, Laura D. Wandner, Lynn L. DeBar

“…The trial compares (1) an 8-session, one-on-one, professionally delivered telephonic/video CBT-CP program; and (2) a previously developed and tested 8-session online CBT-CP-based program (painTRAINER) to (3) usual care augmented by a written guide for chronic pain management. Participants are followed for 1 year post-allocation and are assessed at baseline, and 3, 6, and 12 months post-allocation. …”
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