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    Functional Ultrasound Imaging Reveals Activation Properties of Clinical Spinal Cord Stimulation Therapy Programming by Lim K, Slee SJ, Kibler A, Falowski S, Amirdelfan K

    Published 2025-02-01
    Subjects: “…high frequency and multi-frequency scs paradigms. results: scs stimulation resulted in significant activation of the sdh in differing patterns across two vertebral segments. the magnitude and volume of ∆sbv increased at higher amplitudes and was typically maximal in the sdh regions underlying the active electrodes. therapy mode significantly influenced total area and depth of ∆sbv. multiphase therapy produced the largest area of ∆sbv followed by multi-frequency and other scs modes. multiphase therapy also produced the greatest depth of ∆sbv followed by multi-frequency and burst therapies. conclusions: this work demonstrates that fus can effectively measure scs neural response patterns in the pain processing laminae of a large animal model implanted with a clinical scs system. hemodynamic responses in the sc varied significantly across scs therapy modes…”
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