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Hepatitis B Virus Genotype D: An Overview of Molecular Epidemiology, Evolutionary History, and Clinical Characteristics
Published 2023-04-01“…We have additionally explored recent paleogenomic findings, which facilitated the detection of HBV/D genomes dating back to the late Iron Age and provided new perspectives on the origins of modern HBV/D strains. …”
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82
Convergent Mutations and Single Nucleotide Variants in Mitochondrial Genomes of Modern Humans and Neanderthals
Published 2024-03-01“…The genetic contributions of Neanderthals to the modern human genome have been evidenced by the comparison of present-day human genomes with paleogenomes. Neanderthal signatures in extant human genomes are attributed to intercrosses between Neanderthals and archaic anatomically modern humans (AMHs). …”
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83
Domestication of farmed fish via the attenuation of stress responses mediated by the hypothalamus–pituitary–inter-renal endocrine axis
Published 2022-07-01“…Over recent decades, growing evidence implicating the attenuation of the HPA/I axis during the domestication of animals have been identified through comprehensive genomic analyses of the paleogenomic datasets of wild progenitors and their domestic congeners. …”
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84
Genomic Approaches Reveal an Endemic Subpopulation of Gray Wolves in Southern China
Published 2019-10-01“…Our study is the first to survey museum gray wolves' genomes from Southern China, highlighting how sequencing the paleogenome from museum specimens can help us to study extinct species. : Biological Sciences; Genomics; Evolutionary Biology Subject Areas: Biological Sciences, Genomics, Evolutionary Biology…”
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85
Historical and Modern Classifications of the Plague Agent
Published 2023-02-01“…The review presents the data on domestic and foreign phenotypic classifications of Yersinia pestis strains developed in the XX century; genetic classifications of the XXI century; as well as on the genealogy of ancient strains of the plague microbe, reconstructed using paleogenomic technologies. Since the discovery of the plague agent in 1894, many classifications were created that corresponded to the level of development of microbiology at that time. …”
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86
Extended longevity of DNA preservation in Levantine Paleolithic sediments, Sefunim Cave, Israel
Published 2022-08-01“…Abstract Paleogenomic research can elucidate the evolutionary history of human and faunal populations. …”
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87
Genome-wide analysis of nearly all the victims of a 6200 year old massacre.
Published 2021-01-01“…Paleogenomic and bioanthropological studies of ancient massacres have highlighted sites where the victims were male and plausibly died all in battle, or were executed members of the same family as might be expected from a killing intentionally directed at subsets of a community, or where the massacred individuals were plausibly members of a migrant community in conflict with previously established groups, or where there was evidence that the killing was part of a religious ritual. …”
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88
5000 years of dietary variations of prehistoric farmers in the Great Hungarian Plain.
Published 2018-01-01“…Although there has been considerable research into the dietary changes associated with the initial spread of farming, less attention has been given to how dietary choices continued to develop during subsequent millennia. A paleogenomic time transect for 5 millennia of human occupation in the Great Hungarian Plain spanning from the advent of the Neolithic to the Iron Age, showed major genomic turnovers. …”
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89
Incidence of ancient variants associated with oncological diseases in modern populations
Published 2023-12-01“…Data on germline mutations in tumour suppressor genes in ancient human genomes are scarce and their historic prevalence gives insights into the evolution of predisposition to cancer disease and hence helps advance paleogenomic medicine.…”
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90
Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene.
Published 2007-10-01“…Following an in silico paleogenomic strategy based on genome-wide searches for paralog sequences, we discovered that opossum and wallaby nPE2 sequences are highly similar to members of the superfamily of CORE-short interspersed nucleotide element (SINE) retroposons, in particular to MAR1 retroposons that are widely present in marsupial genomes. …”
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91
Modern Diagnostic Technologies in the Study of the Field Material Collected from the Natural Plague Foci of the Kyrgyz Republic in 2023
Published 2024-01-01“…Areas of the territory of the KR that are promising for paleogenomic research are also discussed.…”
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