Transosseous Multiple Finger Flexor Tendon Pulley Reconstruction by Michael Simon MD, Christoph Lutter MD, Thomas Tischer MD, PhD, Volker Schöffl MD, PhD

“…Technique Description: Standard palmar-sided incision, followed by debridement of the tendon sheath, pulley flap, and, if applicable, scare tissue in between the flexor tendons and the bone is performed. …”
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Evaluation of hand functions and distal radioulnar joint instability in elite wheelchair basketball athletes: a cross-sectional pilot study by Hiroshi Yuine, Hirotaka Mutsuzaki, Yuichi Yoshii, Yukiyo Shimizu, Natsuki Ishida, Taku Yasuda, Koichi Iwai, Kazushi Hotta, Hideki Shiraishi, Kaori Tachibana

“…Hand functions were evaluated based on the range of motion (ROM) of wrist palmar flexion, dorsiflexion, radial deviation, and ulnar deviation; grip strength; arm circumference; forearm circumference; and DRUJ instability or pain using the ballottement test. …”
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Cost-effectiveness of SAPIEN 3 transcatheter aortic valve implantation in low surgical mortality risk patients in Spain by José Manuel Vázquez Rodríguez, Eduardo Pinar Bermúdez, José Luis Zamorano, José Moreu Burgos, José Francisco Díaz-Fernández, Bruno García del Blanco, Archita Sarmah, Pascal Candolfi, Judith Shore, Michelle Green

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Quality Assessment of Hand Hygiene and Effectiveness of WHO 6 Step Training among Healthcare Personnel in a Tertiary Care Cancer Hospital in Trivandrum, India: A Cross-sectional St... by Deepthi J Prabhu, Munish Palliyalil Kakkolil, Divya V Gladston, Rachel Cherian Koshy, Jagathnath KM Krishna, Ashish Mathew

“…Pass criteria allowed a maximum of two small uncovered areas (dark spots <0.6 cm2) on the dorsal side of the hand and no uncovered areas on the palmar aspect. Each hand was observed specifically at four areas and the most missed areas were identified. …”
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Efficacy and safety of PD-1/PD-L1 inhibitor combined with chemotherapy versus chemotherapy alone in the treatment of advanced gastric or gastroesophageal junction adenocarcinoma: a... by Bo-Wei Liu, Qi-Xing Shang, Yu-Shang Yang, Long-Qi Chen

“…However, immunotherapy combined with chemotherapy increased the incidence of adverse reactions such as alanine aminotransferase elevation (OR = 1.55 [95% CI: 1.17–2.07]; p = 0.003) and palmar-plantar erythrodysesthesia (PPE) syndrome (OR = 1.30 [95% CI: 1.05–1.63]; p = 0.02). …”
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Evaluation of a Comprehensive Profile of Salivary Analytes for the Diagnosis of the Equine Gastric Ulcer Syndrome by Alberto Muñoz-Prieto, José J. Cerón, Camila P. Rubio, María Dolores Contreras-Aguilar, Luis Pardo-Marín, Ignacio Ayala-de la Peña, María Martín-Cuervo, Ida-Marie Holm Henriksen, Julián J. Arense-Gonzalo, Fernando Tecles, Sanni Hansen

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Pegylated Liposomal Doxorubicin (Caelyx^®) as Adjuvant Treatment in Early-Stage Luminal B-like Breast Cancer: A Feasibility Phase II Trial by Silvia Dellapasqua, Pamela Trillo Aliaga, Elisabetta Munzone, Vincenzo Bagnardi, Eleonora Pagan, Emilia Montagna, Giuseppe Cancello, Raffaella Ghisini, Claudia Sangalli, Mara Negri, Manuelita Mazza, Monica Iorfida, Anna Cardillo, Angela Sciandivasci, Nadia Bianco, Ana Paula De Maio, Monica Milano, Giuseppe Maria Campennì, Loredana Sansonno, Giuseppe Viale, Anna Morra, Maria Cristina Leonardi, Viviana Galimberti, Paolo Veronesi, Marco Colleoni

“…Most common AEs were palmar-plantar erythrodysesthesia (12.2%), fatigue (10.4%), and mucositis (8.5%). …”
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Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma by Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon

“…Primary outcome was objective response rate (ORR); secondary outcomes were progression-free survival (PFS) and overall survival (OS).Results In total, 325 patients were included: 234 (72%) plantar, 69 (21%) subungual and 22 (7%) palmar primary sites. First CPI included: 184 (57%) anti-PD-1, 59 (18%) anti-PD-1/ipilimumab combination and 82 (25%) ipilimumab. …”
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Factors Associated with Re‐Displacement after Nonsurgical Treatment of Distal Radius Fractures in Adults: A Retrospective Study by Hong‐zhou Zhao, Jian‐ge Chen, Hai‐ning Zhang, Jia‐hui Xing, Ming‐jun Liu, Wei‐min Wang

“…There were no statistically significant differences (p > 0.05) between the two groups in terms of gender, external fixation method, and palmar tilt angle at pre‐reduction and immediate reduction, while significant differences (p < 0.05) were observed in age, side, AO/OTA type, and radial inclination, radial length, and radiographic outcomes of ulnar variance at pre‐reduction and immediate reduction. …”
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Systemic taurine treatment affords functional and morphological neuroprotection of photoreceptors and restores retinal pigment epithelium function in RCS rats by Ana Martínez-Vacas, Johnny Di Pierdomenico, Alejandro Gallego-Ortega, Francisco J. Valiente-Soriano, Manuel Vidal-Sanz, Serge Picaud, María Paz Villegas-Pérez, Diego García-Ayuso

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Polypharmacy and adverse events in atrial fibrillation: Main cause or reflection of multimorbidity? by Lorena Martínez-Montesinos, José Miguel Rivera-Caravaca, Stefan Agewall, Eva Soler, Gregory Y.H. Lip, Francisco Marín, Vanessa Roldán

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Factors Associated with Withdrawal Time in European Colonoscopy Practice: Findings of the European Colonoscopy Quality Investigation (ECQI) Group by Cristiano Spada, Anastasios Koulaouzidis, Cesare Hassan, Pedro Amaro, Anurag Agrawal, Lene Brink, Wolfgang Fischbach, Matthias Hünger, Rodrigo Jover, Urpo Kinnunen, Akiko Ono, Árpád Patai, Silvia Pecere, Lucio Petruzziello, Jürgen F. Riemann, Harry Staines, Ann L. Stringer, Ervin Toth, Giulio Antonelli, Lorenzo Fuccio

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Dosimetric parameters in congenital cardiac catheterizations in Spain: the GTH-SECPCC Radcong-21 multicenter registry by Fernando Rueda Núñez, César Abelleira Pardeiro, Beatriz Insa Albert, María Álvarez-Fuente, Vanesa Balboa Barreiro, Fernando Ballesteros Tejerizo, Pedro Betrián-Blasco, Félix Coserría Sánchez, Juana María Espín López, Luis Fernández González, Dolores Herrera Linde, Miguel Romero Moreno, Fernando Sarnago Cebada, Ricardo Sanz-Ruiz, Juan Ignacio Zabala Argüelles

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A Middle-Late Devonian fish fauna from the Sierra de Perijá, western Venezuela, South America by G. C. Young, J. M. Moody

“…A new Devonian fossil fish fauna from the region of Caño Colorado between the Rio Palmar and Rio Socuy, Sierra de Perijá, Venezuela, comes from two localities and several horizons within the Campo Chico Formation, dated on plants and spores as Givetian-Frasnian in age. …”
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Trends in hospitalisation for ischaemic stroke in young adults in the region of Murcia (Spain) between 2006 and 2014 by A.B. Maldonado-Cárceles, L. Hernando-Arizaleta, J.A. Palomar-Rodríguez, A. Morales-Ortiz

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Integrated Genomic Analysis of Chromosomal Alterations and Mutations in B-Cell Acute Lymphoblastic Leukemia Reveals Distinct Genetic Profiles at Relapse by Maribel Forero-Castro, Adrián Montaño, Cristina Robledo, Alfonso García de Coca, José Luis Fuster, Natalia de las Heras, José Antonio Queizán, María Hernández-Sánchez, Luis A. Corchete-Sánchez, Marta Martín-Izquierdo, Jordi Ribera, José-María Ribera, Rocío Benito, Jesús M. Hernández-Rivas

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Real-world prostate-specific antigen reduction and survival outcomes of metastatic hormone-sensitive prostate cancer patients treated with apalutamide: An observational, retrospect... by Alicia López-Abad, Miguel Ramírez Backhaus, Gerardo Server Gómez, Enrique Cao Avellaneda, Cristóbal Moreno Alarcón, Pedro López Cubillana, Pablo Yago Giménez, Pedro de Pablos Rodríguez, María J. Juan Fita, Miguel Á. Climent Durán, Iris Guardiola Ruiz, Natalia Vidal Crespo, Miriam Artés Artés, Raúl Montoya Chinchilla, Juan Moreno Avilés, Pablo L. Guzmán Martínez-Valls, Pedro Á. López González

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First occurrence of <i>Panthera atrox</i> (Felidae, Pantherinae) in the Mexican state of Hidalgo and a review of the record of felids from the Pleistocene of Mexico by V. M. Bravo-Cuevas, J. Priego-Vargas, M. Á. Cabral-Perdomo, M. A. Pineda Maldonado

“…atrox</i>: a large, robust, and non-strongly curved lower canine; a large and relatively slender fifth metacarpal with a well-developed projection on the palmar side at the proximal end, narrow articulating surface for the unciform; a narrow notch on the articulating surface for the fourth metacarpal; and a diaphysis that at the middle is oval in cross section. …”
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Adverse events of bevacizumab for triple negative breast cancer and HER-2 negative metastatic breast cancer: A meta-analysis by Xueqiong Xun, Jun Ai, Fuhui Feng, Pan Hong, Saroj Rai, Ruikang Liu, Baowen Zhang, Yeming Zhou, Huiyong Hu

“…Of all graded ≥3 AEs, proteinuria (RR = 9.22, 95%CI 4.49–18.93, Rate: 4.22% vs. 0.38%), mucosal inflammation (RR = 8.12, 95%CI 2.46–26.77, Rate: 3.49% vs. 0.43%), palmar-plantar erythrodysesthesia syndrome (RR = 6.95, 95%CI 2.47–19.57, Rate: 6.01% vs. 0.87%), increased Alanine aminotransferase (ALT) (RR = 6.95, 95%CI 1.59–30.38, Rate: 3.13% vs. 0.24%) and hypertension (RR = 4.94, 95%CI 3.84–6.35, Rate: 9.44% vs. 2.02%) had the top five risk ratios.Conclusion: The addition of Bevacizumab for TNBC and HER-2 negative MBC patients showed an increased incidence of AEs especially for grade ≥3 AEs. …”
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Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 studyResear... by Marwan Fakih, Kanwal Pratap Singh Raghav, David Z. Chang, Tim Larson, Allen L. Cohn, Timothy K. Huyck, David Cosgrove, Joseph A. Fiorillo, Rachel Tam, David D'Adamo, Neelesh Sharma, Barbara J. Brennan, Ying A. Wang, Sabine Coppieters, Hong Zebger-Gong, Anke Weispfenning, Henrik Seidel, Bart A. Ploeger, Udo Mueller, Carolina Soares Viana de Oliveira, Andrew Scott Paulson

“…The most common (≥20%) events were fatigue (26/70), palmar-plantar erythrodysesthesia syndrome (19/70), maculopapular rash (17/70), increased blood bilirubin (14/70), and decreased appetite (14/70). …”
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