IMMEDIATE AND LONGTERM RESULTS OF ENDOVASCULAR STENT-GRAFTING IN DISSECTIONS AND ATHEROSCLEROTIC ANEURYSMS OF THORACIC AORTA by Kyaw K. Latt, Alexey A. Moiseev, Natalya R. Chernaya, Konstantin N. Vasilyev, Nikolay L. Bayandin, Viktor A. Stupin

“…In-hospital mortality was 4 (14,2 %) and 30-day mortality was 3 (10,7 %). Events of paraplegia, TIA (Transient Ischemic Attack), prosthetic infection were not found in our research. …”
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Catheter-Related Urinary Tract Infection in Patients Suffering from Spinal Cord Injuries by Amela Dedeić-Ljubović, Mirsada Hukić

“…Urinary tract infection is commoner in patients with spinal cord injuries because of incomplete bladder emptying and the use of catheters that can result in the introduction of bacteria into the bladder. 145 patients suffering from spinal cord injuries, admitted to the Institute for physical medicine and rehabilitation, Centre for paraplegia of the Clinical Centre of the University of Sarajevo, were included. …”
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MIELITE TRANSVERSA POR HERPES VÍRUS: RELATO DE CASO by Guilherme Dorneles Zinelli, Maria Carolina Rey Alt, Bruna Kochhann Menezes, Viviane Raquel Buffon

“…A despeito disso, a necessidade de um rápido diagnóstico é crucial para evitar paraplegia e morte. Relato de caso: Paciente masculino de 24 anos, previamente hígido, descreve sinais e sintomas inespecíficos de febre, mialgia e surgimento de exantema maculopapular em membros superiores e dorso, evoluindo com dificuldade de micção e evacuação, sendo, por diversas vezes, realizado sondagem vesical de alívio e tratado, empiricamente, para infecção urinária. …”
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Diagnostic utility of exome sequencing for inherited peripheral neuropathies by O. A. Shchagina, O. P. Ryzhkova, A. L. Chukhrova, T. V. Milovidova, P. Gundorova, O. L. Mironovich, A. A. Orlova, M. D. Orlova, A. V. Poliakov

“…Among the causal variants, mutations in B4GALNT1 caused spastic paraplegia, in COL6A1 led to Bethlem’s congenital muscular dystrophy, and in SYT2 caused congenital myasthenic syndrome indicating difficulties in differential diagnosis of inherited neuromuscular disorders. …”
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Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion by Rossella Spataro, Maria Kousi, Sali M. K. Farhan, Jason R. Willer, Jay P. Ross, Patrick A. Dion, Guy A. Rouleau, Mark J. Daly, Benjamin M. Neale, Vincenzo La Bella, Nicholas Katsanis

“…Conclusions We here expand the phenotypic spectrum associated with genetic variants in ATP13A2 that previously comprised Kufor-Rakeb syndrome, spastic paraplegia 78, and neuronal ceroid lipofuscinosis type 12 (CLN12), to also include juvenile-onset ALS, as supported by both genetic and functional data. …”
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Hours and costs of formal and informal care following Traumatic Brain Injury and Spinal Cord Injury sustained through Motor Vehicle Accidents: A Cross-sectional Study by Robert Gordon, Grahame K. Simpson, Josephine M. Paasila

“…Results: Spinal cord injury (tetraplegia/ paraplegia) was significantly more expensive for both formal and informal care compared with traumatic brain injury. …”
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Clinical Characterization and Founder Effect Analysis in Chinese Patients with Phospholipase A2-Associated Neurodegeneration by Hao-Ling Cheng, Yi-Jun Chen, Yan-Yan Xue, Zhi-Ying Wu, Hong-Fu Li, Ning Wang

“…Interestingly, we found that one patient had hereditary spastic paraplegia and showed various atypical clinical characteristics of PLAN, and five patients had a phenotype of parkinsonism. …”
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Experience with aortic arch inclusion technique using artificial blood vessel for type A aortic dissection: an application study by Qingfeng Li, Bin Li, Shuqiang Xi, Zhaobin Li, Zhe Zhu, Zeyue Jin, Fan Yang, Lei Liu

“…Other notable complications included two cases of postoperative renal failure necessitating continuous renal replacement therapy (CRRT), one case of postoperative double lower limb paraplegia, and one case of cerebral infarction resulting in unilateral impairment of the left upper limb. …”
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Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology by Barış Genç, Mukesh Gautam, Öge Gözütok, Ina Dervishi, Santana Sanchez, Gashaw M. Goshu, Nuran Koçak, Edward Xie, Richard B. Silverman, P. Hande Özdinler

“…Their degeneration is a hallmark for diseases, such as hereditary spastic paraplegia (HSP), primary lateral sclerosis (PLS), and amyotrophic lateral sclerosis (ALS). …”
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Quality of life improvement in people with spinal cord injury: The transition from rehabilitation hospital to the everyday life from users’ perspective La mejora de la calidad de v... by Mariona Gifre Monreal, Arantza del Valle Gómez, Mercè Yuguero Rueda, Angel Gil Origüen, Pilar Monreal Bosch

“…Two discussion groups, one formed by 12 people with paraplegia, and another formed by 6 people with tetraplejia, have been carried out. …”
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Effect of Reciprocating Gait Orthosis with Hip Actuation on Upper Extremity Loading during Ambulation in Patient with Spinal Cord Injury: A Single Case Study by Jong-Won Lee, Juhwan Bae, Hyuk-Jae Choi, Chilyong Kwon, Yoon Heo, Hyeonseok Cho, Gyoosuk Kim

“…We believe that a substantial reduction in upper extremity loading during ambulation provided by hip actuation holds promise to promote long-term RGO use and enable patients with paraplegia to perform frequent and intensive rehabilitation training. …”
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Incremental medical cost of delirium in elderly patients with cognitive impairment: analysis of a nationwide administrative database in Japan by Shigeru Tokita, Kotoba Okuyama, Yasuyuki Okumura, Naoya Ueda, Masakazu Igarashi, Hideki Sano, Kanae Takahashi, Zaina P Qureshi, Asao Ogawa, Shoki Okuda

“…Subgroup analyses revealed significantly higher total medical costs for patients with delirium compared with those without delirium in most subgroups except patients with hemiplegia or paraplegia.Conclusions Medical costs during hospitalisation were significantly higher for patients with delirium compared with those without delirium in elderly Japanese patients with cognitive impairment, regardless of patient subgroups such as age, sex, intensive care unit admission and most comorbidities. …”
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Development of versatile allele-specific siRNAs able to silence all the dominant dynamin 2 mutations by Swati Dudhal, Lylia Mekzine, Bernard Prudhon, Karishma Soocheta, Bruno Cadot, Kamel Mamchaoui, Delphine Trochet, Marc Bitoun

“…Dominant DNM2 mutations also cause rare forms of Charcot-Marie-Tooth disease and hereditary spastic paraplegia, and deleterious DNM2 overexpression was noticed in several diseases. …”
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Microscopic and Biochemical Hallmarks of <i>BICD2</i>-Associated Muscle Pathology toward the Evaluation of Novel Variants by Andreas Unger, Andreas Roos, Andrea Gangfuß, Andreas Hentschel, Dieter Gläser, Karsten Krause, Kristina Doering, Ulrike Schara-Schmidt, Sabine Hoffjan, Matthias Vorgerd, Anne-Katrin Güttsches

“…<i>BICD2</i> variants have been linked to neurodegenerative disorders like spinal muscular atrophy with lower extremity predominance (SMALED2) or hereditary spastic paraplegia (HSP). Recently, mutations in <i>BICD2</i> were implicated in myopathies. …”
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Case report: A case of acute disseminated encephalomyelitis after SARS-CoV-2 infection in pediatric patients by Francesca Cautilli, Mariavittoria Feleppa, Massimiliano Valeriani, Laura Papetti, Gabriele Monte, Fabio Midulla, Alberto Spalice

“…Neurological symptoms began with headache, fever, irritability, paraplegia, and loss of sensitivity from the T1 level. …”
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KIF1A-Associated Neurological Disorder: An Overview of a Rare Mutational Disease by Ayushi Nair, Alosh Greeny, Rajalakshmi Rajendran, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Roshni Pushpa Raghavan, Sachithra Thazhathuveedu Sudevan, Bijo Mathew, Hoon Kim

“…Variations in the <i>KIF1A</i> gene, which primarily affect the motor domain, disrupt its ability to transport synaptic vesicles containing synaptophysin and synaptotagmin leading to various neurological pathologies such as hereditary sensory neuropathy, autosomal dominant and recessive forms of spastic paraplegia, and different neurological conditions. These mutations are frequently misdiagnosed because they result from spontaneous, non-inherited genomic alterations. …”
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Development and Validation of a Risk Nomogram Model for Predicting Community-Acquired Pressure Injury Among the Older Adults in China: A Case-Control Study by Zhang ZL, Hu XX, Yang HL, Wang D

“…A nomogram was constructed including eight variables: age ≥ 80, malnutrition status, cerebrovascular accidents, hypoproteinemia, respiratory failure, malignant tumor, paraplegia/hemiplegia, and dementia. The AUC of the prediction model in the original model, internal validation, and external validation were 0.868 (95% CI: 0.847, 0.890), mean 0.867, and 0.840 (95% CI: 0.807,03.873), respectively. …”
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Accuracy of Heart Rate Measurement by the Fitbit Charge 2 During Wheelchair Activities in People With Spinal Cord Injury: Instrument Validation Study by Dirk Hoevenaars, Iris E Yocarini, Stylianos Paraschiakos, Jasmijn F M Holla, Sonja de Groot, Wessel Kraaij, Thomas W J Janssen

“…The accuracy was just above the acceptable level in people with paraplegia, whereas in people with tetraplegia, a worse accuracy was found. …”
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Secondary Open Aortic Procedure Following Thoracic Endovascular Aortic Repair: Meta‐Analytic State of the Art by Ivancarmine Gambardella, George A. Antoniou, Francesco Torella, Cristiano Spadaccio, Aung Y. Oo, Mario Gaudino, Francesco Nappi, Matthew A. Shaw, Leonard N. Girardi

“…Neurological morbidity was substantial between stroke (5.1%, 2.8–9.1) and paraplegia (8.3%, 5.2–13.1). At 2‐year follow‐up, mortality (20.4%, 11.5–33.5) and aortic adverse event (aortic death 7.7%, 4.3–13.3, tertiary aortic open procedure 7.4%, 4.0–13.2) were not negligible. …”
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Prediction model for spinal cord injury in spinal tuberculosis patients using multiple machine learning algorithms: a multicentric study by Sitan Feng, Shujiang Wang, Chong Liu, Shaofeng Wu, Bin Zhang, Chunxian Lu, Chengqian Huang, Tianyou Chen, Chenxing Zhou, Jichong Zhu, Jiarui Chen, Jiang Xue, Wendi Wei, Xinli Zhan

“…Abstract Spinal cord injury (SCI) is a prevalent and serious complication among patients with spinal tuberculosis (STB) that can lead to motor and sensory impairment and potentially paraplegia. This research aims to identify factors associated with SCI in STB patients and to develop a clinically significant predictive model. …”
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