Cranio-cervical decompression associated with non-instrumented occipito-C2 fusion in children with mucopolysaccharidoses: Report of twenty-one cases by Mohamed Zairi, Ahmed Msakni, Ahmed Amin Mohseni, Nesrine Nessib, Sofiene Bouali, Rim Boussetta, Mohamed Nabil Nessib

“…As major complications, a child had immediate post-operative paraplegia due to spinal cord ischemia. The postoperative follow-up ranged from 1.5 to 4 years, with an average of 3.3 years. …”
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Multiple Bone Destruction Secondary to <i>Mycobacterium kansasii</i> Pulmonary Disease: A Case Report by Lu Dai, Yanyan Wu, Xi Zhou, Sen Liu, Junping Fan, Huaiya Xie, Luo Wang, Xinlun Tian, Wenbing Xu

“…The patient underwent an emergency operation after experiencing unexpected incomplete paraplegia during hospitalization, indicating an aggravation of bone destruction. …”
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OSTEOMIELITE SACRAL- INFECÇÃO DE DIFÍCIL TRATAMENTO by Bruna de Brito Silva Fernandes, Otilia Lupi, Magda de Souza da Conceição, Marcelo Gomes dos Santos

“…No pós-operatório evoluiu com paraplegia e extensa lesão por pressão sacral com osteomielite. …”
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Incidence and prevalence of traumatic spinal cord injury in Canada using health administrative data by Nancy P. Thorogood, Vanessa K. Noonan, Xiaozhi Chen, Nader Fallah, Nader Fallah, Suzanne Humphreys, Nicolas Dea, Brian K. Kwon, Brian K. Kwon, Marcel F. Dvorak, Marcel F. Dvorak

“…The estimated number of people living with TSCI was 30,239 (804/million); 15,533 (52%) with paraplegia and 14,706 (48%) with tetraplegia. Trends included an increase in the number of people injured each year from 874 to 1,199 incident cases (37%), an older average age at injury rising from 46.6 years to 54.3 years and a larger proportion over the age of 65 changing from 22 to 38%, during the 15-year time frame.ConclusionThis study provides a standard method for calculating the incidence and prevalence of TSCI in Canada using national-level health administrative data. …”
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A Consecutive 25-Week Program of Gait Training, Using the Alternating Hybrid Assistive Limb (HAL^®) Robot and Conventional Training, and its Effects on the Walking Abilit... by Atsushi Kanazawa, Kenichi Yoshikawa, Kazunori Koseki, Ryoko Takeuchi, Hirotaka Mutsuzaki

“…<i>Materials and Methods:</i> Clinical features of this patient&#8217;s paraplegia were as follows: neurological level, T7; American Spinal Cord Injury Association Impairment Scale Score, C; Lower Extremity Motor Score, 20 points; Berg Balance Scale score, 15 points; and Walking Index for Spinal Cord Injury, 6 points. …”
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Cure of recurring Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae septic shock episodes due to complicated soft tissue infection using a ceftazidime and avibact... by Giustino Parruti, Antonella Frattari, Ennio Polilli, Vincenzo Savini, Antonina Sciacca, Augusta Consorte, Donatella Concetta Cibelli, Adriana Agostinone, Francesco Di Masi, Alessandro Pieri, Pierluigi Cacciatore, Giancarlo Di Iorio, Paolo Fazii, Tullio Spina

“…Case presentation A Caucasian 53-year-old man with paraplegia suffered multiple vertebral fractures due to a car crash. …”
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The surgical management of congenital kyphosis and kyphoscoliosis by McMaster, Michael J., Harwant Singh

“…Congenital kyphosis and kyphoscoliosis are much less common than congenital scoliosis but potentially more serious, because these curves can progress rapidly and Type I deformities can lead to spinal cord compression and paraplegia. No one operative procedure can be applied to all types and sizes of deformity. …”
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Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device by Petroula Nana, Konstantinos Spanos, Tomasz Jakimowicz, Jose I. Torrealba, Katarzyna Jama, Giuseppe Panuccio, Fiona Rohlffs, Tilo Kölbel

“…SCI rate was 14.7%, (4.8% paraplegia rate) with 22.2% of patients receiving prophylactic cerebrospinal drainage. …”
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Dynamics of independence and locomotor capabili- ties caused by powered exoskeleton-induced walk training in patients with severe chronic spinal cord injury by Elena Yu. Shapkova, Dmitry V. Emelyannikov, Yulia E. Larionova, Nikita A. Kupreev, Ekaterina V. Grigoreva

“…To evaluate the effectiveness of complex rehabilitation with walk training induced by powered exoskeleton ‘ExoAtlet’ for the patients with severe chronic paraplegias caused by thoracic or upper lumbar spine injuries. …”
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Early outcome of simplified total arch reconstruction under mild hypothermia (30–32 °C) with distal aortic perfusion by Hua-Jie Zheng, Xin Liu, Ping He, Jun Li, Xian-Pu Zhang, Yong-Bo Cheng, De-Qing Lin, Chao-Jun Yan, San-Jiu Yu, Wei Cheng

“…The mean duration of mechanical ventilation was shorter in the s-TAR group. Paraplegia was observed in 4 of 105 patients (3.8%) in the c-TAR group, while no such events were observed in the s-TAR group. …”
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Single-center experience with thoracoabdominal aortic replacement in patients with Marfan syndromeCentral MessagePerspective by Saad Rustum, MD, Osama Zahlout, MD, Andreas Martens, MD, Tim Kaufeld, MD, Heike Krüger, RN, Linda Rudolph, MS, Axel Haverich, MD, PhD, Malakh Shrestha, MBBS, PhD, Erik Beckmann, MD, PhD

“…One (1.7%) patient had permanent paraplegia and 2 (3%) permanent paraparesis. Two (3%) patients had stroke. …”
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Intramedullary Spinal Cord Abscess with Concomitant Spinal Degenerative Diseases: A Case Report and Systematic Literature Review by Redwan Jabbar, Bartosz Szmyd, Jakub Jankowski, Weronika Lusa, Agnieszka Pawełczyk, Grzegorz Wysiadecki, R. Shane Tubbs, Joe Iwanaga, Maciej Radek

“…The follow-up MRI showed improvement, but the patient’s paraplegia persisted. In light of his persistent hypoesthesia and paraplegic gait with developing neuropathic pain, he was readmitted, and an MRI of his lumbar spine revealed multilevel degenerative disease and tethered spinal cord syndrome with compression of the medulla at the L2–L3 level. …”
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Email-Based Recruitment Into the Health eHeart Study: Cohort Analysis of Invited Eligible Patients by Madelena Y Ng, Jeffrey E Olgin, Gregory M Marcus, Courtney R Lyles, Mark J Pletcher

“…The odds of registration were lower among those with medical conditions such as dementia, chronic pulmonary disease, moderate or severe liver disease, paraplegia or hemiplegia, renal disease, or cancer. …”
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Single-center initial experience with inner-branch complex EVAR in 44 patients by Marvin Kapalla, Albert Busch, Brigitta Lutz, Heiner Nebelung, Steffen Wolk, Christian Reeps

“…There was no in-hospital mortality. Permanent paraplegia developed in 6.8% (n = 3) of patients. The mean follow-up was 12 months (range 0–52 months). …”
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Development of a High-Power Capacity Open Source Electrical Stimulation System to Enhance Research into FES-Assisted Devices: Validation of FES Cycling by Tiago Coelho-Magalhães, Emerson Fachin-Martins, Andressa Silva, Christine Azevedo Coste, Henrique Resende-Martins

“…A volunteer with complete paraplegia participated in the functional testing of the system. …”
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Plasma CHI3L1 in Amyotrophic Lateral Sclerosis: A Potential Differential Diagnostic Biomarker by Alessandro Bombaci, Umberto Manera, Giovanni De Marco, Federico Casale, Paolina Salamone, Giuseppe Fuda, Giulia Marchese, Barbara Iazzolino, Laura Peotta, Cristina Moglia, Andrea Calvo, Adriano Chiò

“…We evaluated the plasmatic levels of CHI3L1 in MNDs, MND mimics, and healthy controls (HCs). (2) Methods: We used a sandwich ELISA to quantify the CHI3L1 in plasma samples from 44 MND patients, 7 hereditary spastic paraplegia (HSP) patients, 9 MND mimics, and 19 HCs. …”
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Computational study of the motor neuron protein KIF5A to identify nsSNPs, bioactive compounds, and its key regulators by Rupesh Kumar, Thirumurthy Madhavan, Kalaiarasan Ponnusamy, Honglae Sohn, Shazia Haider

“…Variations in the KIF5A gene that interfere with axonal transport have emerged as a distinguishing feature in several neurodegenerative disorders, including hereditary spastic paraplegia (HSP10), Charcot-Marie-Tooth disease type 2 (CMT2), and Amyotrophic Lateral Sclerosis (ALS).Methods: In this study, we implemented a computational structural and systems biology approach to uncover the role of KIF5A in ALS. …”
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Case Report: Aicardi-Goutières Syndrome Type 6 and Dyschromatosis Symmetrica Hereditaria With Congenital Heart Disease and Mitral Valve Calcification – Phenotypic Variants Caused b... by Lingjuan Liu, Lingjuan Liu, Lu Zhang, Lu Zhang, Peng Huang, Peng Huang, Jie Xiong, Jie Xiong, Yangyang Xiao, Yangyang Xiao, Cheng Wang, Cheng Wang, Dingan Mao, Dingan Mao, Liqun Liu, Liqun Liu

“…The pathogenic gene is adenosine deaminase acting on the RNA 1 gene (ADAR1), mutations in this gene also lead to Aicardi-Goutières syndrome type 6 (AGS 6), a rare hereditary encephalopathy with isolated spastic paraplegia. The pathomechanism of the ADAR1 gene mutations inducing DSH has not been clarified yet. …”
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Risk Factors for Postoperative Deep Infection after Instrumented Spinal Fusion Surgeries for Degenerative Spinal Disease: A Nationwide Cohort Study of 194,036 Patients by Jihye Kim, Tae-Hwan Kim

“…The final multivariable model identified the following variables as significant risk factors for postoperative deep infection: age between 60–69 years (OR = 1.6 [1.1–2.3]); age between 70–79 years (OR = 1.7 [1.2–2.5]); age > 80 years (OR = 2.1 [1.3–3.2]); male sex (OR = 1.7 [1.5–2.0]); rural residence (OR = 1.3 [1.1–1.5]); anterior cervical approach (OR = 0.2 [0.1–0.3]); posterior cervical approach (OR = 0.5 [0.2–1.0]); multiple approaches (OR = 1.4 [1.2–1.6]); cerebrovascular disease (OR = 1.5 [1.2–1.8]); peripheral vascular disease (OR = 1.3 [1.1–1.5]); chronic pulmonary disease (OR = 1.2 [1.0–1.4]); rheumatologic disease (OR = 1.6 [1.3–2.1]); liver disease (OR = 1.4 [1.1–1.7]); diabetes (OR = 1.5 [1.3–1.7]); hemiplegia or paraplegia (OR = 2.2 [1.5–3.3]); allogenous transfusion (OR = 1.6 [1.3–1.8]); and use of systemic steroids over 2 weeks (OR = 1.5 [1.1–2.0]). …”
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Association of variants in the KIF1A gene with amyotrophic lateral sclerosis by Panlin Liao, Yanchun Yuan, Zhen Liu, Xiaorong Hou, Wanzhen Li, Jin Wen, Kexuan Zhang, Bin Jiao, Lu Shen, Hong Jiang, Jifeng Guo, Beisha Tang, Zhuohua Zhang, Zhonghua Hu, Junling Wang

“…Notably, sensory and motor neuron diseases such as hereditary sensory and autonomic neuropathy type 2 (HSAN2) and spastic paraplegia 30 (SPG30) share several causative genes with ALS, as well as having common clinical phenotypes. …”
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