Method development for quantification of DMET-proteins in the paediatric intestinal tract via LC-MS/MS using a QconCAT technique by Jan Goelen, Richard D Horniblow, Hannah Batchelor

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Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study by Karen Rowland Yeo, Oliver Hatley, Ben G. Small, Trevor N. Johnson

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Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood C... by Matthias Van der Veken, Joachim Brouwers, Agustos Cetin Ozbey, Kenichi Umehara, Cordula Stillhart, Noël Knops, Patrick Augustijns, Neil John Parrott

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Development and Performance Verification of the PBPK Model for Antazoline and Its Metabolite and Its Utilization for Pharmacological Hypotheses Formulating by Barbara Wiśniowska, Joanna Giebułtowicz, Roman Piotrowski, Piotr Kułakowski, Sebastian Polak

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PBPK Modelling of Dexamethasone in Patients With COVID-19 and Liver Disease by Maiara Camotti Montanha, Nicolas Cottura, Michael Booth, Daryl Hodge, Fazila Bunglawala, Hannah Kinvig, Sandra Grañana-Castillo, Andrew Lloyd, Saye Khoo, Marco Siccardi

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The Use of a Physiologically Based Pharmacokinetic Modelling in a “Full-Chain” Exposure Assessment Framework: A Case Study on Urban and Industrial Pollution in Northern Italy by Lorenzo Vaccari, Andrea Ranzi, Annamaria Colacci, Grazia Ghermandi, Sergio Teggi

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Physiologically Based Pharmacokinetic Modelling and Simulation to Predict the Plasma Concentration Profile of Doxorubicin by George A. Mystridis, Georgios C. Batzias, Ioannis S. Vizirianakis

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PBPK modelling of ceftriaxone Na-loaded starch-sodium alginate polymeric blend prepared by water-in-oil emulsification for oral delivery by Hina Raza, Yusra Ilahi, Zermina Rashid, Shabnam Nazir, Suryyia Manzoor, Mohamed Deifallah Yousif

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Prospects and limitations of physiologically-based pharmacokinetic modelling for cross-species extrapolation by Lars Kuepfer

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Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid by Miro Julian Eigenmann, Tine Veronica Karlsen, Marek Wagner, Olav Tenstad, Tina Weinzierl, Tanja Fauti, Hans Peter Grimm, Trude Skogstrand, Christian Klein, Johannes Sam, Pablo Umana, Marina Bacac, Helge Wiig, Antje-Christine Walz

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SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator by Hiba Khalidi, Anthonia Onasanwo, Barira Islam, Heeseung Jo, Ciarán Fisher, Rich Aidley, Iain Gardner, Frederic Y. Bois

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Application of Modelling and Simulation Approaches to Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies in Pediatric Population by Andrew Lim, Pradeep Sharma, Oleg Stepanov, Venkatesh Pilla Reddy

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Integrating In Vitro Biopharmaceutics into Physiologically Based Biopharmaceutic Model (PBBM) to Predict Food Effect of BCS IV Zwitterionic Drug (GSK3640254) by Konstantinos Stamatopoulos, Paola Ferrini, Dung Nguyen, Ying Zhang, James M. Butler, Jon Hall, Nena Mistry

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Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants—A Contribution... by Martje Van Neste, Annick Bogaerts, Nina Nauwelaerts, Julia Macente, Anne Smits, Pieter Annaert, Karel Allegaert

Subjects: “…physiologically based pharmacokinetic (PBPK) modelling and simulation…”
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On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development by Patrick J. O’Dwyer, Georgios Imanidis, Karl J. Box, Christos Reppas

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A physiologically based pharmacokinetic model of clopidogrel in populations of European and Japanese ancestry: An evaluation of CYP2C19 activity by Janna K. Duong, Romina A. Nand, Aarti Patel, Oscar Della Pasqua, Annette S. Gross

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Advancements in Virtual Bioequivalence: A Systematic Review of Computational Methods and Regulatory Perspectives in the Pharmaceutical Industry by Nasser Alotaiq, Doni Dermawan

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Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling—A Contribution from the ConcePTION Project by Nina Nauwelaerts, Julia Macente, Neel Deferm, Rodolfo Hernandes Bonan, Miao-Chan Huang, Martje Van Neste, David Bibi, Justine Badee, Frederico S. Martins, Anne Smits, Karel Allegaert, Thomas Bouillon, Pieter Annaert

Subjects: “…physiologically-based pharmacokinetic (PBPK) modelling and simulation…”
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Health Risk Assessment of Ortho-Toluidine Utilising Human Biomonitoring Data of Workers and the General Population by Pasi Huuskonen, Spyros Karakitsios, Bernice Scholten, Joost Westerhout, Dimosthenis A. Sarigiannis, Tiina Santonen

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Prediction of pediatric dose of tirzepatide from the reference adult dose using physiologically based pharmacokinetic modelling by Ruifang Guan, Ruifang Guan, Xuening Li, Guo Ma

Subjects: “…physiologically based pharmacokinetic (PBPK) modelling…”
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