Trends and Correlation Between Antimicrobial Resistance and Antibiotics Consumption in a Specialist Children’s Hospital from 2016 to 2021 by Gong W, Tang W, Luo L, Zhang F, Cai C, Zhang J, Wu X, Shang J, Shu X, Wang T, Tu D, Jin Z, Zheng R

“…Wenting Gong,1,* Wen Tang,2,* Lan Luo,3 Furong Zhang,1 Chenyang Cai,1 Jiangyan Zhang,1 Xiaolin Wu,4 Jianping Shang,4 Xiaolan Shu,2 Ting Wang,5 Danna Tu,6 Zhengjiang Jin,7,* Ronghao Zheng4,* 1Department of pharmacy, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Pediatric Intensive Care Unit, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 3Department of Child Health, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 4Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 5Department of Pediatric Neurology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 6Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 7Department of Clinical Laboratory, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ronghao Zheng, Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, 745 Wu luo Road, Hongshan District, Wuhan, 430070, Hubei Province, People’s Republic of China, Tel +86 02787169267, Email hytwo2001@126.com Zhengjiang Jin, Department of Clinical Laboratory, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, 745 Wu luo Road, Hongshan District, Wuhan, 430070, Hubei Province, People’s Republic of China, Email king199735@126.comPurpose: To explore the trends and correlation between antibiotics consumption and antimicrobial resistance in children in a specialist hospital from 2016– 2021 in China.Patients and Methods: This retrospective study investigated data on the consumption of antibiotics and antimicrobial resistance in children. …”
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Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease by Jun Dong, Li Chen, Fei Ye, Junhui Tang, Bing Liu, Jiacheng Lin, Pang-Hu Zhou, Bin Lu, Min Wu, Jia-Hong Lu, Jing-Jing He, Simone Engelender, Qingtao Meng, Zhiyin Song, He He

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Lung Ultrasound in Pediatric Acute Respiratory Distress Syndrome Received Extracorporeal Membrane Oxygenation: A Prospective Cohort Study by Yucai Zhang, Yucai Zhang, Chunxia Wang, Chunxia Wang, Chunxia Wang, Fei Wang, Jingyi Shi, Jiaying Dou, Jiaying Dou, Yijun Shan, Ting Sun, Yiping Zhou

“…ObjectiveThe aim of this study was to assess the prognostic value of the lung ultrasound (LUS) score in patients with pediatric acute respiratory distress syndrome (pARDS) who received extracorporeal membrane oxygenation (ECMO).MethodsA prospective cohort study was conducted in a pediatric intensive care unit (PICU) of a tertiary hospital from January 2016 to June 2021. …”
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Pediatric Intensive Care: Immunomodulation With Activated Protein C ex vivo by Hassan O. Eliwan, Hassan O. Eliwan, Hassan O. Eliwan, Hassan O. Eliwan, William R. G. Watson, Irene Regan, Brian Philbin, Fiona M. O'Hare, Fiona M. O'Hare, Fiona M. O'Hare, Tammy Strickland, Amanda O'Neill, Michelle O'Rourke, Alfonso Blanco, Martina Healy, Beatrice Nolan, Owen Smith, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy

“…Objective: Sepsis is major cause of morbidity and mortality in the Pediatric Intensive Care Unit (PICU). PICU patients may develop transient immune deficiency during sepsis. …”
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A Proof of Concept of the Role of TDM-Based Clinical Pharmacological Advices in Optimizing Antimicrobial Therapy on Real-Time in Different Paediatric Settings by Milo Gatti, Milo Gatti, Pier Giorgio Cojutti, Caterina Campoli, Fabio Caramelli, Luigi Tommaso Corvaglia, Luigi Tommaso Corvaglia, Marcello Lanari, Marcello Lanari, Andrea Pession, Andrea Pession, Stefania Ramirez, Pierluigi Viale, Pierluigi Viale, Federico Pea, Federico Pea

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Suporte farmacológico a lactentes e crianças com choque séptico Pharmacologic support of infants and children in septic shock by José Irazuzta, Kevin J. Sullivan, Pedro Celiny R. Garcia, Jefferson Pedro Piva

“…<br>OBJECTIVES: Septic shock (SS) is a frequent cause for admission to the pediatric intensive care unit, requiring prompt recognition and intervention to improve outcome. …”
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Non-dipping blood pressure pattern in pediatricians during on-duty by Javier Gonzalez-Garcia, Juan Mayordomo-Colunga, Manuel Gorostidi, Belen Gomez-Gonzalez, Eva Canteli, Corsino Rey

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An effort to reduce chest compression pauses during automated external defibrillator use among laypeople: A randomized partially blinded controlled trial by Cristian Abelairas-Gómez, Aida Carballo-Fazanes, Santiago Martínez-Isasi, Sergio López-García, Antonio Rodríguez-Núñez

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Status epilepticus in BRAF‐related cardio‐facio‐cutaneous syndrome: Focus on neuroimaging clues to physiopathology by Elisa Musto, Maria Luigia Gambardella, Marco Perulli, Michela Quintiliani, Chiara Veredice, Tommaso Verdolotti, Giovanna Berté, Chiara Leoni, Roberta Onesimo, Silvia Maria Pulitanò, Marco Tartaglia, Giuseppe Zampino, Ilaria Contaldo, Domenica Immacolata Battaglia

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Outcomes of neonatal congenital diaphragmatic hernia in a non-ECMO center in a middle-income country: a retrospective cohort study by Lucy Chai See Lum, Tindivanum Muthurangam Ramanujam, Yee Ian Yik, Mei Ling Lee, Soo Lin Chuah, Emer Breen, Anis Siham Zainal-Abidin, Srihari Singaravel, Conjeevaram Rajendrarao Thambidorai, Jessie Anne de Bruyne, Anna Marie Nathan, Surendran Thavagnanam, Kah Peng Eg, Lucy Chan, Mohamed E. Abdel-Latif, Chin Seng Gan

“…Methods We retrospectively reviewed the medical notes of neonates with unilateral CDH admitted to a pediatric intensive care unit (PICU) in a tertiary referral center over a 15-year period, from 2003–2017. …”
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Gut Microbiota Diversity of Preterm Neonates Is Associated With Clostridioides Difficile Colonization by Jeanne Couturier, Jeanne Couturier, Patricia Lepage, Sarah Jolivet, Johanne Delannoy, Victoria Mesa, Pierre-Yves Ancel, Pierre-Yves Ancel, Jean-Christophe Rozé, Marie-José Butel, Frédéric Barbut, Frédéric Barbut, Frédéric Barbut, Julio Aires

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Non-dipping blood pressure pattern in pediatricians during on-duty by Javier Gonzalez-Garcia, Juan Mayordomo-Colunga, Manuel Gorostidi, Belen Gomez-Gonzalez, Eva Canteli, Corsino Rey

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The international effort: building the bridge for Translational Medicine: Report of the 1st International Conference of Translational Medicine (ICTM) by Xiaoming Chen, Roland Andersson, William CS Cho, David Christiani, Richard Coico, Jeffery Drazen, Markus Ege, Thomas Fehniger, Hongwei Gao, Kunlin Jin, Michael N Liebman, Elena Lopez, Giuseppe Marraro, Gyorgy Marko‐Varga, Francesco M Marincola, Laurentiu M Popescu, Claudio Spada, Aamir Shahzad, Ena Wang, Wei Wang, Xiangdong Wang, Yong‐Xiao Wang, Jinglin Xia, Jia Qu

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Associação entre ângulo de fase, PRISM I e gravidade da sepse Association between phase angle, PRISM I and sepsis severity by Zina Maria Almeida de Azevedo, Dilma Ribeiro Silva, Maria Virgínia P. Dutra, Maria Ignêz C. Gaspar Elsas, Maria Cristina G. Barbosa-Silva, Vânia Matos Fonseca

“…METHODS: A transversal study was performed at the Pediatric Intensive Care Unit (PICU) in Instituto Fernandes Figueira. …”
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Mortality prediction in pediatric postcardiotomy veno-arterial extracorporeal membrane oxygenation: A comparison of scoring systems by Yu Jin, Peng Gao, Peiyao Zhang, Liting Bai, Yixuan Li, Wenting Wang, Zhengyi Feng, Xu Wang, Jinping Liu

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The Clinical Characteristics of ARDS in Children With Hematological Neoplasms by Qiao Zhang, Wen-ting Hu, Fan Yin, Han Qian, Ying Wang, Bi-ru Li, Juan Qian, Yan-jing Tang, Bo-tao Ning, Bo-tao Ning

“…In order to explore the clinical characteristics of pediatric patients admitted to the pediatric intensive care unit (PICU) who suffered from hematological neoplasms complicated with acute respiratory distress syndrome (ARDS), we retrospectively analyzed 45 ARDS children with hematological neoplasms who were admitted to the PICU of Shanghai Children's Medical Center from January 1, 2014, to December 31, 2020. …”
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Uso de diagramas de controle na vigilância epidemiológica das infecções hospitalares Use of statistical process control charts in the epidemiological surveillance of nosocomial inf... by Aglai Arantes, Eduardo da Silva Carvalho, Eduardo Alexandrino Servolo Medeiros, Calil Kairalla Farhat, Orlando César Mantese

“…METHODS: Between January 1998 and December 2000 nosocomial infection occurrence was evaluated in a cohort of 460 patients admitted to the Pediatric Intensive Care Unit of a university hospital, according to the concepts and criteria proposed by the National Nosocomial Infection Surveillance System of the Centers for Disease Control, in the United States. …”
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Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 by Natalia Vélez-Tirado, Lina Castaño-Jaramillo, Sonia Restrepo-Gualteros, Catalina Alcalá-Lozano, Erika Ruge, Carolina Puente, Diana Li-Zeng, Diego Chaparro-Arce, María Camila Beltrán-Dimas, Juan Francisco López, Miguel Luengas-Monroy, Diego Galvis-Trujillo, Iván Gutiérrez-Tobar, Pablo Vásquez-Hoyos, Germán Camacho-Moreno

“…Ninetyseven percent were admitted to the pediatric intensive care unit, 94% required respiratory support, and the in-hospital lethality rate was 11%. …”
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Adverse events related to central venous catheters (CVC) and the influence of CVC characteristics on peripheral blood hematopoietic progenitor cell collection in children by Josune Zubicaray, Sofía Martin-Consuegra, Monserrat Nieto, Gustavo Albi, June Iriondo, Elena Sebastian, Eva Gálvez, Blanca Molina, Marta González-Vicent, Jesus Gonzalez de Pablo, Ana Castillo, Manuel Ramírez, Luis Madero, Luis Madero, Luis Madero, Miguel Angel Díaz, Julián Sevilla

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A Comparison of Parenteral Phenobarbital vs. Parenteral Phenytoin as Second-Line Management for Pediatric Convulsive Status Epilepticus in a Resource-Limited Setting by Richard J. Burman, Richard J. Burman, Sally Ackermann, Alexander Shapson-Coe, Alvin Ndondo, Alvin Ndondo, Heloise Buys, Jo M. Wilmshurst, Jo M. Wilmshurst

“…Secondary outcomes included the need for admission to the pediatric intensive care unit (PICU) and breakthrough seizures during the admission. …”
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