Meropenem for children with severe pneumonia: Protocol for a randomized controlled trial by Xue Tian, Lei Dong, Ting-Ting Jiang, Bo-Hao Tang, Ze-Ming Wang, Yue-E Wu, Dian-Ping You, Jing Bi, Su-Yun Qian, Hui Qi, A-Dong Shen, A-Dong Shen

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Risk factors for central venous catheter-related infections in pediatric intensive care Fatores de risco para as infecções relacionadas ao caracter venoso central em terapia intens... by Ricardo Vilela, Andréa D N Jácomo, Antonia Teresinha Tresoldi

“…METHOD: After reviewing the charts of patients who developed catheter-related infection in a university hospital's pediatric intensive care unit, we conducted a case-controlled study with 51 pairs. …”
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Case report: Aggressive progression of acute heart failure due to juvenile tuberculosis-associated Takayasu arteritis with aortic stenosis and thrombosis by Wenjie Xuan, Wenjie Xuan, Zhaoling Wang, Jinjing Lin, Jinjing Lin, Lixia Zou, Xisheng Xu, Xinghui Yang, Yiping Xu, Yan Zhang, Qi Zheng, Xuefeng Xu, Meiping Lu

“…We report a case of tuberculosis (TB)-associated TA with aggressive acute heart failure (AHF), pulmonary hypertension (PH), thrombosis, and seizure, who failed to survive after surgery.Case presentationA 10-year-old boy who developed a cough with chest tightness, shortness of breath, hemoptysis with reduced left ventricular ejection fraction, PH, and increased C-reactive protein and erythrocyte sedimentation rate was hospitalized at the pediatric intensive care unit of our hospital. He had strongly positive purified protein derivative skin test and interferon-gamma release assay result. …”
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Malformações detectadas pelo ultrassom abdominal em crianças com cardiopatia congênita Malformations detected by abdominal ultrasound in children with congenital heart disease by Rosana Cardoso Manique Rosa, Rafael Fabiano Machado Rosa, José Antônio Monteiro Flores, Eliete Golendziner, Ceres Andréia Vieira de Oliveira, Marileila Varella-Garcia, Giorgio Adriano Paskulin, Paulo Ricardo Gazzola Zen

“…The cases consisted of patients with CHD admitted for the first time in a pediatric intensive care unit; the controls consisted of children without CHD who underwent AUS at the hospital shortly thereafter a case. …”
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Severe fever with thrombocytopenia syndrome virus induces platelet activation and apoptosis via a reactive oxygen species-dependent pathway by Yi-Hui Li, Xue-Hui Wang, Wen-Wu Huang, Ren-Rong Tian, Wei Pang, Yong-Tang Zheng

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Does Skin Bathing With Chlorhexidine Gluconate (2%) Affect the Carbapenem-resistant Enterobacteriaceae and Vancomycin-resistant Enterococcus Colonization in Pediatric Intensive Car... by Sevgi TOPAL, Gülhan ATAKUL, Mustafa ÇOLAK, Ekin SOYDAN, Özlem SANDAL, Gökhan CEYLAN, Utku KARAARSLAN, Nevbahar YAŞAR, Elif BÖNCÜOĞLU, İlker DEVRİM, Fahri Yüce AYHAN, Hasan AĞIN

“…Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococcus (VRE) colonization and infections are important in the pediatric intensive care unit (PICU). This study aimed to investigate the effect of a 2% chlorhexidine gluconate (CHG) bath on VRE and CRE colonization. …”
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Increase of Parkin and ATG5 plasmatic levels following perinatal hypoxic-ischemic encephalopathy by Anna Tarocco, Giampaolo Morciano, Mariasole Perrone, Claudia Cafolla, Cristina Ferrè, Tiziana Vacca, Ginevra Pistocchi, Fabio Meneghin, Ilaria Cocchi, Gianluca Lista, Irene Cetin, Pantaleo Greco, Giampaolo Garani, Marcello Stella, Miria Natile, Gina Ancora, Immacolata Savarese, Francesca Campi, Iliana Bersani, Andrea Dotta, Eloisa Tiberi, Giovanni Vento, Elisabetta Chiodin, Alex Staffler, Eugenia Maranella, Sandra Di Fabio, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton

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Early Diagnosis and Prognostic Value of Acute Kidney Injury in Critically Ill Patients by Diana Dobilienė, Jūratė Masalskienė, Šarūnas Rudaitis, Astra Vitkauskienė, Jurgita Pečiulytė, Rimantas Kėvalas

“…<i>Materials and methods:</i> This single-center prospective observational study included 107 critically ill children aged from 1 month to 18 years, who were treated in the Pediatric Intensive Care Unit (PICU) of Lithuanian University of Health Sciences Hospital Kauno Klinikos from 1 December 2013, to 30 November 2016. …”
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Prevalence and factors associated with trajectories of antenatal depression: a prospective multi-center cohort study in Chengdu, China by Xiuhua Huang, Ying Wang, Yuqiong Wang, Xiujing Guo, Ling Zhang, Wenxia Wang, Jing Shen

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Evolução e característica de lactantes com bronquiolite viral aguda submetidos à ventilação mecânica em uma unidade de terapia intensiva pediátrica brasileira Outcome and character... by Fernanda Umpierre Bueno, Jefferson Pedro Piva, Pedro Celiny Ramos Garcia, Patrícia Miranda Lago, Paulo Roberto Einloft

“…METHODS: We performed a retrospective study enrolling all infants (less than 12 months old) admitted with the diagnosis of acute viral bronchiolitis and submitted to mechanical ventilation in an university affiliated Brazilian pediatric intensive care unit between March, 2004 and September, 2006 (3 consecutives winters). …”
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Canadian Association of Paediatric Nephrologists COVID-19 Rapid Response: Guidelines for Management of Acute Kidney Injury in Children by Abdullah Alabbas, Amrit Kirpalani, Catherine Morgan, Cherry Mammen, Christoph Licht, Veronique Phan, Andrew Wade, Elizabeth Harvey, Michael Zappitelli, Edward G. Clark, Swapnil Hiremath, Steven D. Soroka, Ron Wald, Matthew A. Weir, Rahul Chanchlani, Mathieu Lemaire

“…Implications: Given that most acute KRT related to COVID-19 is likely to be required in the pediatric intensive care unit initial setting, close collaboration and planning between critical care and pediatric nephrology programs are needed. …”
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Knowledge, Attitude, and Practice About Antibiotic Use and Antimicrobial Resistance Among Nursing Students in China: A Cross Sectional Study by Yang C, Xie J, Chen Q, Yuan Q, Shang J, Wu H, Yang Y, Wang M, Shu X, Yue J, Tu D, Lin Y, Zheng R, Wu X

“…Chaoping Yang,1,&ast; Jing Xie,2,&ast; Qianjun Chen,2 Qiongyin Yuan,3 Jianping Shang,4 Haibo Wu,5 Youhua Yang,6 Mingfang Wang,7 Xiaolan Shu,8 Jing Yue,9 Danna Tu,10 Ying Lin,1,&ast; Ronghao Zheng,4,&ast; Xiaolin Wu4 1Nursing Department, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Hubei University of Medicine, Shiyan, Hubei, People’s Republic of China; 3Obstetrical department, Huanggang Maternal and Child Health Hospital, Hubei, People’s Republic of China; 4Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 5School of Health and Nursing, Wuchang University of Technology, Wuhan, People’s Republic of China; 6Department of Basic Medical Sciences, School of Medicine, Jianghan University, Wuhan, People’s Republic of China; 7Department of Pediatric Gastroenterology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 8Department of Pediatric Intensive Care Unit (PICU), Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 9Emergency Department, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China; 10Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ronghao Zheng, Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, 745 Wu Luo Road, Hongshan District, Wuhan, Hubei Province, 430070, People’s Republic of China, Email hytwo2001@126.com Ying Lin, Nursing department, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China, Email 523933025@qq.comPurpose: The knowledge, attitude, and practices (KAP) concerning antibiotics by healthcare students have the potential impact on controlling antibiotic abuse and antimicrobial resistance (AMR) growth. …”
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A phase II dose evaluation pilot feasibility randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study) by Katie O’Hearn, Kusum Menon, Hope A. Weiler, Karin Amrein, Dean Fergusson, Anna Gunz, Raul Bustos, Roberto Campos, Valentina Catalan, Siegfried Roedl, Anne Tsampalieros, Nick Barrowman, Pavel Geier, Matthew Henderson, Ali Khamessan, Margaret L. Lawson, Lauralyn McIntyre, Stephanie Redpath, Glenville Jones, Martin Kaufmann, Dayre McNally, the Canadian Critical Care Trials Group

“…Abstract Background Vitamin D deficiency (VDD) is highly prevalent in the pediatric intensive care unit (ICU) and associated with worse clinical course. …”
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Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time... by Giuseppe Maglietta, Matteo Puntoni, Caterina Caminiti, Andrea Pession, Marcello Lanari, Fabio Caramelli, Federico Marchetti, Alessandro De Fanti, Lorenzo Iughetti, Giacomo Biasucci, Giacomo Biasucci, Agnese Suppiej, Andrea Miceli, Chiara Ghizzi, Gianluca Vergine, Melodie Aricò, Marcello Stella, Susanna Esposito, Susanna Esposito, on behalf of Emilia-Romagna Paediatric COVID-19 network

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Variabilidade na determinação do ponto externo de referência para a medida de pressão venosa central em crianças Variability in the establishment of an external reference point for... by Aline S. C. Belela, Mavilde L. G. Pedreira, Maria Angélica S. Peterlini, Denise M. Kusahara, Werther B. Carvalho, Gisele C. Gentil

“…METHODS: Descriptive and correlational study carried out in a pediatric intensive care unit of a teaching hospital. During the establishment of the midaxillary line as ERP for central venous pressure measurement, five assessments of the same patient made by healthcare workers and one assessment made by a trained evaluator were compared. …”
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The Role of Muscle Biopsy in Diagnostic Process of Infant Hypotonia: From Clinical Classification to the Genetic Outcome by Marco Veneruso, Chiara Fiorillo, Chiara Fiorillo, Paolo Broda, Serena Baratto, Monica Traverso, Alice Donati, Salvatore Savasta, Raffaele Falsaperla, Maria Margherita Mancardi, Marina Pedemonte, Chiara Panicucci, Gianluca Piatelli, Mattia Pacetti, Andrea Moscatelli, Luca Antonio Ramenghi, Lino Nobili, Lino Nobili, Carlo Minetti, Carlo Minetti, Claudio Bruno, Claudio Bruno

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Prominent and Regressive Brain Developmental Disorders Associated with Nance-Horan Syndrome by Celeste Casto, Valeria Dipasquale, Ida Ceravolo, Antonella Gambadauro, Emanuela Aliberto, Karol Galletta, Francesca Granata, Giorgia Ceravolo, Emanuela Falzia, Antonella Riva, Gianluca Piccolo, Maria Concetta Cutrupi, Pasquale Striano, Andrea Accogli, Federico Zara, Gabriella Di Rosa, Eloisa Gitto, Elisa Calì, Stephanie Efthymiou, Vincenzo Salpietro, Henry Houlden, Roberto Chimenz

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Distribution and Magnitude of Regional Volumetric Lung Strain and Its Modification by PEEP in Healthy Anesthetized and Mechanically Ventilated Dogs by Joaquin Araos, Pablo Cruces, Pablo Cruces, Manuel Martin-Flores, Pablo Donati, Robin D. Gleed, Tomas Boullhesen-Williams, Agustin Perez, Francesco Staffieri, Jaime Retamal, Jaime Retamal, Marcos F. Vidal Melo, Daniel E. Hurtado, Daniel E. Hurtado

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Malformações detectadas pelo ultrassom abdominal em crianças com cardiopatia congênita Malformations detected by abdominal ultrasound in children with congenital heart disease by Rosana Cardoso Manique Rosa, Rafael Fabiano Machado Rosa, José Antônio Monteiro Flores, Eliete Golendziner, Ceres Andréia Vieira de Oliveira, Marileila Varella-Garcia, Giorgio Adriano Paskulin, Paulo Ricardo Gazzola Zen

“…The cases consisted of patients with CHD admitted for the first time in a pediatric intensive care unit; the controls consisted of children without CHD who underwent AUS at the hospital shortly thereafter a case. …”
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Molecular Changes in Prepubertal Left Ventricular Development Under Experimental Volume Overload by Yuqing Hu, Debao Li, Chunxia Zhou, Yingying Xiao, Sijuan Sun, Chuan Jiang, Chuan Jiang, Chuan Jiang, Lijun Chen, Jinfen Liu, Hao Zhang, Hao Zhang, Fen Li, Haifa Hong, Lincai Ye, Lincai Ye, Lincai Ye

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