The gut microbiota mediates protective immunity against tuberculosis via modulation of lncRNA by Fang Yang, Yi Yang, Lingming Chen, Zhiyi Zhang, Linna Liu, Chunmin Zhang, Qiongdan Mai, Yiwei Chen, Zixu Chen, Tao Lin, Liang Chen, Huixin Guo, Lin Zhou, Hongbo Shen, Xinchun Chen, Lei Liu, Guoliang Zhang, Hongying Liao, Lingchan Zeng, Gucheng Zeng

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Day‐1 PELOD‐2 and day‐1 “quick” PELOD‐2 scores in children with sepsis in the PICU by Mianling Zhong, Yuge Huang, Tufeng Li, Lu Xiong, Ting Lin, Miaofen Li, Dongqiang He

“…Objectives: This study aimed to evaluate the predictive validity of the day‐1 PELOD‐2 and day‐1 “quick” PELOD‐2 (qPELOD‐2) scores for in‐hospital mortality in children with sepsis in a pediatric intensive care unit (PICU) of a developing country. …”
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Carbapenem-resistant Enterobacteriaceae bloodstream infections: A case-control study from a pediatric referral hospital in Argentina by Silvina Ruvinsky, Carla Voto, Macarena Roel, Verónica Deschutter, Daiana Ferraro, Norma Aquino, Vanesa Reijtman, María Eugenia Galvan, Eduardo Motto, Mauro García, Claudia Sarkis, Rosa Bologna

“…A total of 54.3% of cases vs. 32.6 % (p = 0.016) of controls were admitted to the pediatric intensive care unit (PICU), and 48 vs. 21% (p = 0.001) required mechanical ventilation. …”
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Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group by Roberto Grandinetti, Valentina Fainardi, Carlo Caffarelli, Gaia Capoferri, Angela Lazzara, Marco Tornesello, Aniello Meoli, Barbara Maria Bergamini, Luca Bertelli, Loretta Biserna, Paolo Bottau, Elena Corinaldesi, Nicoletta De Paulis, Arianna Dondi, Battista Guidi, Francesca Lombardi, Maria Sole Magistrali, Elisabetta Marastoni, Silvia Pastorelli, Alessandra Piccorossi, Maurizio Poloni, Sylvie Tagliati, Francesca Vaienti, Giuseppe Gregori, Roberto Sacchetti, Sandra Mari, Manuela Musetti, Francesco Antodaro, Andrea Bergomi, Lamberto Reggiani, Fabio Caramelli, Alessandro De Fanti, Federico Marchetti, Giampaolo Ricci, Susanna Esposito, on behalf of the Emilia-Romagna Asthma (ERA) Study Group

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Treatment and outcomes of 1041 pediatric patients with neuroblastoma who received multidisciplinary care in China by Yan Su, Hong Qin, Chenghao Chen, Shengcai Wang, Shihan Zhang, Dawei Zhang, Mei Jin, Yun Peng, Lejian He, Xiaoman Wang, Suyun Qian, Maoquan Qin, Ming Ge, Fuquan Zhang, Qi Zeng, Huanmin Wang, Xiaoli Ma, Xin Ni

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Lactato sérico como marcador de morbimortalidade no pós-operatório de operação de Jatene em lactentes Serum lactate as mortality and morbidity marker in infants after Jatene's oper... by Taís Sica da Rocha, Alan Soares da Silveira, Aline Medeiros Botta, Cláudia Pires Ricachinevsky, Lisiane Dalle Mulle, Aldemir Nogueira

“…METHODS: We performed a historical cohort with infants admitted in a pediatric intensive care unit during 1995 to 2005 who underwent this surgery. …”
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Case Report: Severe ARDS in a Pediatric Hematopoietic Stem-Cell Transplantation Recipient Caused by Disseminated Toxoplasmosis by Sara de la Mata Navazo, Sara de la Mata Navazo, Sara de la Mata Navazo, Sara de la Mata Navazo, María Slöcker Barrio, María Slöcker Barrio, María Slöcker Barrio, María Slöcker Barrio, Marina García-Morín, Marina García-Morín, Marina García-Morín, Cristina Beléndez, Cristina Beléndez, Cristina Beléndez, Laura Escobar Fernández, Elena María Rincón-López, Elena María Rincón-López, Elena María Rincón-López, David Aguilera Alonso, David Aguilera Alonso, David Aguilera Alonso, Jesús Guinea, Jesús Guinea, Mercedes Marín, Mercedes Marín, Laura Butragueño-Laiseca, Laura Butragueño-Laiseca, Laura Butragueño-Laiseca, Laura Butragueño-Laiseca, Jesús López-Herce Cid, Jesús López-Herce Cid, Jesús López-Herce Cid, Jesús López-Herce Cid

“…We present the case of a 6-year-old patient with acute lymphoblastic leukemia and HSCT recipient who was admitted to the Pediatric Intensive Care Unit (PICU) on post-transplantation day +39 with fever, hypotension, severe respiratory distress and appearance of a lumbar subcutaneous node. …”
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Management of Central Venous Catheters in Children and Adults on Home Parenteral Nutrition: A French Survey of Current Practice by Julien Gotchac, Florian Poullenot, Dominique Guimber, Emmanuelle Ecochard-Dugelay, Stéphane Schneider, Noël Peretti, Lore Billiauws, Corinne Borderon, Anne Breton, Emilie Chaillou Legault, Cécile Chambrier, Aurélie Comte, Marie-Edith Coste, Djamal Djeddi, Béatrice Dubern, Claire Dupont, Lucile Espeso, Philippe Fayemendy, Nicolas Flori, Ginette Fotsing, Swellen Gastineau, Olivier Goulet, Emeline Guiot, Adam Jirka, Jeanne Languepin, Sabrina Layec, Didier Quilliot, Laurent Rebouissoux, David Seguy, Isabelle Talon, Anne Turquet, Marjolaine Vallee, Stéphanie Willot, Thierry Lamireau, Raphael Enaud

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Comparison of Interleukin-6 Plasma Concentration in Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Pediatric Sepsis by Franco Diaz, Franco Diaz, Franco Diaz, Raúl Bustos B, Raúl Bustos B, Felipe Yagnam, Todd J. Karsies, Pablo Vásquez-Hoyos, Pablo Vásquez-Hoyos, Pablo Vásquez-Hoyos, Juan-Camilo Jaramillo-Bustamante, Juan-Camilo Jaramillo-Bustamante, Juan-Camilo Jaramillo-Bustamante, Sebastián Gonzalez-Dambrauskas, Sebastián Gonzalez-Dambrauskas, Sebastián Gonzalez-Dambrauskas, Michelle Drago, Pablo Cruces, Pablo Cruces, Pablo Cruces

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Predictive Value of Optic Nerve Sheath Diameter for Diagnosis of Intracranial Hypertension in Children With Severe Brain Injury by Fleur Cour-Andlauer, Fleur Cour-Andlauer, Aurélie Portefaix, Aurélie Portefaix, Isabelle Wroblewski, Muriel Rabilloud, Muriel Rabilloud, Muriel Rabilloud, Muriel Rabilloud, Fabienne Bordet, Bérengère Cogniat, Capucine Didier, Robin Pouyau, Frédéric V. Valla, Behrouz Kassai-Koupai, Behrouz Kassai-Koupai, Gaëlle Siméon, Tiphanie Ginhoux, Tiphanie Ginhoux, Sonia Courtil-Teyssedre, Etienne Javouhey, Etienne Javouhey

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Clinical, microbiological, and molecular characterization of pediatric invasive infections by Streptococcus pyogenes in Spain in a context of global outbreak by Eva Ramírez de Arellano, Jesús Saavedra-Lozano, Pilar Villalón, Ana Jové-Blanco, David Grandioso, Jared Sotelo, Anna Gamell, Juan José González-López, Eloísa Cervantes, María José Gónzalez, Victoria Rello-Saltor, Cristina Esteva, Francisco Sanz-Santaeufemia, Genoveva Yagüe, Ángela Manzanares, Patricia Brañas, Enrique Ruiz de Gopegui, Jaime Carrasco-Colom, Federico García, Emilia Cercenado, Isabel Mellado, Elena del Castillo, María Pérez-Vazquez, Jesús Oteo-Iglesias, Cristina Calvo

“…Forty-six of 93 cases (49.5%) required admission to the pediatric intensive care unit. iGAS isolates mainly belonged to emm1 and emm12; emm12 predominated in 2022 but was surpassed by emm1 in 2023. …”
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Biomarkers for the Discrimination of Acute Kawasaki Disease From Infections in Childhood by Judith Zandstra, Annemarie van de Geer, Michael W. T. Tanck, Diana van Stijn-Bringas Dimitriades, Cathelijn E. M. Aarts, Sanne M. Dietz, Robin van Bruggen, Nina A. Schweintzger, Werner Zenz, Marieke Emonts, Dace Zavadska, Marko Pokorn, Effua Usuf, Henriette A. Moll, Luregn J. Schlapbach, Enitan D. Carrol, Stephane Paulus, Maria Tsolia, Colin Fink, Shunmay Yeung, Shunmay Yeung, Chisato Shimizu, Adriana Tremoulet, Rachel Galassini, Victoria J. Wright, Federico Martinón-Torres, Jethro Herberg, Jane Burns, Michael Levin, Taco W. Kuijpers, Taco W. Kuijpers, EUCLIDS Consortium, PERFORM Consortium and UK Kawasaki Disease Genetics Study Network

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Impact of hospital characteristics on implementation of a Pediatric Early Warning System in resource-limited cancer hospitals by Farris Abutineh, Dylan E. Graetz, Hilmarie Muniz-Talavera, Gia Ferrara, Maria Puerto-Torres, Yichen Chen, Srinithya R. Gillipelli, Paul Elish, Alejandra Gonzalez-Ruiz, Yvania Alfonso Carreras, Shillel Alvarez, Daniela Arce Cabrera, Deiby Arguello Vargas, Miriam Armenta Cruz, Camila Barra, Patricia Calderon Sotelo, Zulma Carpio, Mayra Chavez Rios, Daniela Covarrubias, Lucy de Leon Vasquez, Rosdali Diaz Coronado, Ever Amilcar Fing Soto, Wendy Gomez-Garcia, Cinthia Hernandez, María Susana Juarez Tobias, Esmeralda Leon, Jose de Jesus Loeza Oliva, Alejandra Mendez, Kenia Miller, Erika Montalvo Cozar, Natalia del Carmen Negroe Ocampo, Eulalia Penafiel, Estuardo Pineda, Ligia Rios, Esperanza Rodriguez Ordonez, Veronica Soto Chavez, Meenakshi Devidas, Asya Agulnik

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Osteoarticular Infections in Pediatric Hospitals in Europe: A Prospective Cohort Study From the EUCLIDS Consortium by Andreas Trobisch, Andreas Trobisch, Andreas Trobisch, Nina A. Schweintzger, Daniela S. Kohlfürst, Manfred G. Sagmeister, Matthias Sperl, Andrea J. Grisold, Gebhard Feierl, Jethro A. Herberg, Enitan D. Carrol, Stephane C. Paulus, Marieke Emonts, Marieke Emonts, Marieke Emonts, Michiel van der Flier, Michiel van der Flier, Ronald de Groot, Miriam Cebey-López, Miriam Cebey-López, Irene Rivero-Calle, Irene Rivero-Calle, Navin P. Boeddha, Paul-Michael Agapow, Fatou Secka, Suzanne T. Anderson, Uta Behrends, Uwe Wintergerst, Karl Reiter, Federico Martinon-Torres, Federico Martinon-Torres, Michael Levin, Werner Zenz, The EUCLIDS consortium

“…Thirty-five patients were admitted to the Pediatric Intensive Care Unit; out of these, six suffered from shock, one needed an amputation of the right foot and of four left toes, and two had skin transplantation. …”
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Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis by Viktor Kožich, Bernd C Schwahn, Jitka Sokolová, Michaela Křížková, Tamas Ditroi, Jakub Krijt, Youssef Khalil, Tomáš Křížek, Tereza Vaculíková-Fantlová, Blanka Stibůrková, Philippa Mills, Peter Clayton, Kristýna Barvíková, Holger Blessing, Jolanta Sykut-Cegielska, Carlo Dionisi-Vici, Serena Gasperini, Ángeles García-Cazorla, Tobias B Haack, Tomáš Honzík, Pavel Ješina, Alice Kuster, Lucia Laugwitz, Diego Martinelli, Francesco Porta, René Santer, Guenter Schwarz, Peter Nagy

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Does physiological-based cord clamping improve cerebral tissue oxygenation and perfusion in healthy term neonates? – A randomized controlled trial by Bernhard Schwaberger, Bernhard Schwaberger, Bernhard Schwaberger, Mirjam Ribitsch, Gerhard Pichler, Gerhard Pichler, Gerhard Pichler, Marlies Krainer, Marlies Krainer, Marlies Krainer, Alexander Avian, Alexander Avian, Nariae Baik-Schneditz, Nariae Baik-Schneditz, Nariae Baik-Schneditz, Evelyn Ziehenberger, Evelyn Ziehenberger, Evelyn Ziehenberger, Lukas Peter Mileder, Lukas Peter Mileder, Lukas Peter Mileder, Johann Martensen, Johann Martensen, Johann Martensen, Christian Mattersberger, Christian Mattersberger, Christina Helene Wolfsberger, Christina Helene Wolfsberger, Christina Helene Wolfsberger, Berndt Urlesberger, Berndt Urlesberger, Berndt Urlesberger

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Factors Associated With Hospitalization or Intensive Care Admission in Children With COVID-19 in Latin America by Eduardo López-Medina, Eduardo López-Medina, Eduardo López-Medina, German Camacho-Moreno, Martin E. Brizuela, Diana M. Dávalos, Diana M. Dávalos, Juan Pablo Torres, Rolando Ulloa-Gutierrez, Pio López, Pio López, Roberto Debbag, Paola Pérez, Paola Pérez, Jaime Patiño, Jaime Patiño, Ximena Norero, Cristina Mariño, Miguel A. Luengas, Gabriela Ensinck, Carlos Daza, Kathia Luciani, Paola Quintana Kuhner, Mónica Rodriguez, Juan Pablo Rodríguez-Auad, Alejandra Estrada-Villarroel, Mayli Carnevale, Orlando Cesar Mantese, Eitan N. Berezin, José Iván Castillo, Abiel Mascareñas, Andrea Jimenez-Zambrano, Lourdes Dueñas, Mario Melgar, Nancy Galvez, Erika Cantor, Erika Cantor, Edwin J. Asturias, Edwin J. Asturias

“…BackgroundLimited data is available from low-middle and upper-middle income countries of the factors associated with hospitalization or admission to pediatric intensive care unit (PICU) for children with COVID-19.ObjectiveTo describe the factors associated with hospitalization or PICU admission of children with COVID-19 in Latin America.MethodMulticenter, analytical, retrospective study of children reported from 10 different Latin American countries to the Latin-American Society of Pediatric Infectious Diseases (SLIPE-COVID) research network from June 1, 2020, and February 28, 2021. …”
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Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisys... by Luregn J. Schlapbach, Luregn J. Schlapbach, Maya C. Andre, Maya C. Andre, Serge Grazioli, Nina Schöbi, Nina Schöbi, Nicole Ritz, Christoph Aebi, Philipp Agyeman, Manuela Albisetti, Douggl G. N. Bailey, Christoph Berger, Géraldine Blanchard-Rohner, Sabrina Bressieux-Degueldre, Michael Hofer, Michael Hofer, Arnaud G. L'Huillier, Mark Marston, Patrick M. Meyer Sauteur, Jana Pachlopnik Schmid, Marie-Helene Perez, Bjarte Rogdo, Johannes Trück, Johannes Trück, Andreas Woerner, Daniela Wütz, Petra Zimmermann, Petra Zimmermann, Michael Levin, Michael Levin, Elizabeth Whittaker, Elizabeth Whittaker, Peter C. Rimensberger, the PIMS-TS working group of the Interest Group for Pediatric Neonatal Intensive Care (IGPNI) of the Swiss Society of Intensive Care and the Pediatric Infectious Diseases Group Switzerland (PIGS)

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Global PARITY: Study Design for a Multi-Centered, International Point Prevalence Study to Estimate the Burden of Pediatric Acute Critical Illness in Resource-Limited Settings by Qalab Abbas, Adrian Holloway, Paula Caporal, Paula Caporal, Eliana López-Barón, Asya Agulnik, Kenneth E. Remy, Kenneth E. Remy, John A. Appiah, Jonah Attebery, Ericka L. Fink, Jan Hau Lee, Jan Hau Lee, Shubhada Hooli, Niranjan Kissoon, Erika Miller, Srinivas Murthy, Fiona Muttalib, Katie Nielsen, Maria Puerto-Torres, Karla Rodrigues, Firas Sakaan, Adriana Teixeira Rodrigues, Erica A. Tabor, Amelie von Saint Andre-von Arnim, Matthew O. Wiens, Matthew O. Wiens, Matthew O. Wiens, William Blackwelder, David He, Teresa B. Kortz, Teresa B. Kortz, Adnan T. Bhutta, Adnan T. Bhutta

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Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort by Pedro D. Wendel Garcia, Hernán Aguirre-Bermeo, Philipp K. Buehler, Mario Alfaro-Farias, Bernd Yuen, Sascha David, Thomas Tschoellitsch, Tobias Wengenmayer, Anita Korsos, Alberto Fogagnolo, Gian-Reto Kleger, Maddalena A. Wu, Riccardo Colombo, Fabrizio Turrini, Antonella Potalivo, Emanuele Rezoagli, Raquel Rodríguez-García, Pedro Castro, Arantxa Lander-Azcona, Maria C. Martín-Delgado, Herminia Lozano-Gómez, Rolf Ensner, Marc P. Michot, Nadine Gehring, Peter Schott, Martin Siegemund, Lukas Merki, Jan Wiegand, Marie M. Jeitziner, Marcus Laube, Petra Salomon, Frank Hillgaertner, Alexander Dullenkopf, Hatem Ksouri, Sara Cereghetti, Serge Grazioli, Christian Bürkle, Julien Marrel, Isabelle Fleisch, Marie-Helene Perez, Anja Baltussen Weber, Samuele Ceruti, Katharina Marquardt, Tobias Hübner, Hermann Redecker, Michael Studhalter, Michael Stephan, Daniela Selz, Urs Pietsch, Anette Ristic, Antje Heise, Friederike Meyer zu Bentrup, Marilene Franchitti Laurent, Patricia Fodor, Tomislav Gaspert, Christoph Haberthuer, Elif Colak, Dorothea M. Heuberger, Thierry Fumeaux, Jonathan Montomoli, Philippe Guerci, Reto A. Schuepbach, Matthias P. Hilty, Ferran Roche-Campo, RISC-19-ICU Investigators

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