Relaxin-like Gonad-Stimulating Peptides in Asteroidea by Masatoshi Mita

“…Starfish relaxin-like gonad-stimulating peptide (RGP) is the first identified peptide hormone with gonadotropin-like activity in invertebrates. …”
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Inflammation Mediated Hepcidin-Ferroportin Pathway and Its Therapeutic Window in Breast Cancer by Shibabaw T, Teferi B, Molla MD, Ayelign B

“…Thus, hepcidin (Hp) and ferroportin (Fpn) are molecules that regulate and maintain the metabolism of iron. A peptide hormone hepcidin limits recycled and stored iron fluxes in macrophage and hepatic hepatocyte, respectively, to the blood stream by promoting degradation of the only iron exporter, Fpn, in the target cells. …”
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Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart. by Stéphanie C Choisy, Hongwei Cheng, Godfrey L Smith, Andrew F James, Jules C Hancox

“…Although it is known that receptors for the peptide hormone endothelin-1 (ET-1) are expressed in the AVN, there is very little information available on the modulatory effects of ET-1 on AVN electrophysiology. …”
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Membrane Guanylate Cyclase, A Multimodal Transduction Machine: History, Present and Future Directions by Rameshwar K Sharma, Teresa eDuda

“…MGC becomes the transducer of a hormonal signal and founder of the peptide hormone receptor family, and creates the notion that hormone signal transduction is its sole physiological function. …”
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Dhr96[1] mutation and maternal tudor[1] mutation increase life span and reduce the beneficial effects of mifepristone in mated female Drosophila. by Gary N Landis, Hans S Bell, Oscar Peng, Brett Bognar, Andy Tong, Tomás D Manea, Hanmei Bao, Xianlin Han, John Tower

“…Mating and receipt of male Sex Peptide hormone cause increased egg laying, increased midgut size and decreased life span in female Drosophila. …”
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Serum Irisin Predicts Mortality Risk in Acute Heart Failure Patients by Shutong Shen, Rongrong Gao, Yihua Bei, Jin Li, Haifeng Zhang, Yanli Zhou, Wenming Yao, Dongjie Xu, Fang Zhou, Mengchao Jin, Siqi Wei, Kai Wang, Xuejuan Xu, Yongqin Li, Junjie Xiao, Xinli Li

“…Background/Aims: Irisin is a peptide hormone cleaved from a plasma membrane protein fibronectin type III domain containing protein 5 (FNDC5). …”
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Association of serum adropin with risk and severity of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus by Nearmeen M Rashad, Hanan M Sabry, Samir A Afifi, Maha A Fathy

“…Background Diabetic peripheral neuropathy (DPN) is the major microvascular complication of type 2 diabetes mellitus (T2DM). Adropin is a peptide hormone that has essential roles in metabolic homeostasis and the pathogenesis of T2DM and its complications. …”
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Myricetin Increases Circulating Adropin Level after Activation of Glucagon-like Peptide 1 (GLP-1) Receptor in Type-1 Diabetic Rats by Ying-Xiao Li, Kai-Chun Cheng, I-Min Liu, Ho-Shan Niu

“…Moreover, adropin is a nutritionally regulated peptide hormone, which regulates energy metabolism, and plays a role in ameliorating diabetes. …”
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Mesenchymal Stromal Cells for the Treatment of Graft Versus Host Disease by Kilian Kelly, John E. J. Rasko, John E. J. Rasko, John E. J. Rasko

“…MSCs promote an immunosuppressive and immunoregulatory environment via multifactorial mechanisms, including: secretion of proteins/peptides/hormones; transfer of mitochondria; and transfer of exosomes or microvesicles containing RNA and other molecules. …”
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Apo-ghrelin receptor (apo-GHSR1a) Regulates Dopamine Signaling in the Brain by Andras eKern, Cristina eGrande, Roy G Smith

“…The orexigenic peptide hormone ghrelin is synthesized in the stomach and its receptor growth hormone secretagogue receptor (GHSR1a) is expressed mainly in the central nervous system (CNS). …”
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Acylated Ghrelin Level Response to Daily Step in the Post-Menopause Active and Sedentary Elderly Women by Farzad Nazem, Zohreh Hosainzadeh, Mohammad Faramarzi

“…WalkingSince walking is used as a movement current pattern with a different lifestyle conditions, especially in several social jobs activities of daily livings of the middle-aged and elderly, the aim of the present study is to evaluate whether therelationship betweenthe number of step per day steps per day andwith acylated ghrelin of menopausal women is related to different life styles.as well, the effects of physical activity volume on this peptide hormone. Methods & Materials: Daily step volumes voluntarily were measured in the health postmenopausal women (n=40) by the electronic pedometer. …”
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The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line by Mandana Mahmoodzaeh Sagheb, Negar Azarpira, Mokhtar Mokhtary

“…Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. …”
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GIP_HUMAN[22–51] is a new proatherogenic peptide identified by native plasma peptidomics by Tsuguto Masaki, Yoshio Kodera, Michishige Terasaki, Kazumi Fujimoto, Tsutomu Hirano, Masayoshi Shichiri

“…To discover a novel polypeptide that potently modulates the cardiovascular system, we performed a bioinformatics analysis of the large-scale identification results, sequentially synthesized the selected peptide sequences, tested their biological activities, and identified a 30-amino-acid proatherogenic peptide, GIP_HUMAN[22–51], as a potent proatherosclerotic peptide hormone. GIP_HUMAN[22–51] has a common precursor with the glucose-dependent insulinotropic polypeptide (GIP) and is located immediately N-terminal to GIP. …”
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UV-light exposure of insulin: pharmaceutical implications upon covalent insulin dityrosine dimerization and disulphide bond photolysis. by Manuel Correia, Maria Teresa Neves-Petersen, Per Bendix Jeppesen, Søren Gregersen, Steffen B Petersen

“…Continuous UV-excitation of the peptide hormone in solution leads to the progressive formation of tyrosine photo-product dityrosine, formed upon tyrosine radical cross-linkage. …”
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Phosphaturic mesenchymal tumor (PMT): exceptionally rare disease, yet crucial not to miss by Amir Ghorbani-Aghbolagh, Morgan Angus Darrow, Tao Wang

“…The tumor cells produce a peptide hormone-like substance known as fibroblast growth factor 23 (FGF23), a physiologic regulator of phosphate levels. …”
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Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History by Hideaki Kaneto, Tomohiko Kimura, Atsushi Obata, Masashi Shimoda, Kohei Kaku

“…It is also known that metformin reduces food intake and lowers body weight by increasing circulating levels of the peptide hormone growth/differentiation factor 15 (GDF15). …”
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Serum hepcidin levels related to interlukin-6 in patients with acute myeloid leukemia before and after treatment by Khitam Abdulwahhab Ali, Hiba Ammar Mohammad, Alaadin Sahham Naji, Alaa Fadhil Alwan

“…Hepcidin is a small bioactive peptide hormone produced in many tissues mainly by the liver, macrophage, and adipocyte and it has been proposed as a marker of inflammation. …”
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Current and upcoming methods of pharmacotherapy of obesity by Jan Bieniasz, Konrad Dendys, Marcel Kazzi, Michał Puła, Marta Wychota

“…FGF21 is a catabolic peptide hormone, showing a beneficial pleiotropic effect. …”
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HMGB1 induces hepcidin upregulation in astrocytes and causes an acute iron surge and subsequent ferroptosis in the postischemic brain by Dashdulam Davaanyam, Hahnbi Lee, Song-I Seol, Sang-A Oh, Seung-Woo Kim, Ja-Kyeong Lee

“…Abstract Dysregulation of brain iron levels causes functional disturbances and damages neurons. Hepcidin (a peptide hormone) plays a principal role in regulating intracellular iron levels by modulating ferroportin (FPN, the only known iron exporter) through triggering its internalization and lysosomal degradation. …”
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Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts by Herington Adrian C, Collet Chris, Seim Inge, Chopin Lisa K

“…<p>Abstract</p> <p>Background</p> <p>Ghrelin is a multifunctional peptide hormone expressed in a range of normal tissues and pathologies. …”
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