Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. by S Leah Etheridge, Saugata Ray, Shuangding Li, Natasha S Hamblet, Nardos Lijam, Michael Tsang, Michael Tsang, Joy Greer, Natalie Kardos, Jianbo Wang, Daniel J Sussman, Ping Chen, Anthony Wynshaw-Boris

“…Dvl3(-/-) mice died perinatally with cardiac outflow tract abnormalities, including double outlet right ventricle and persistent truncus arteriosis. …”
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Living situation affects adherence to combination antiretroviral therapy in HIV-infected adolescents in Rwanda: a qualitative study. by Philippe R Mutwa, Jennifer Ilo Van Nuil, Brenda Asiimwe-Kateera, Evelyne Kestelyn, Joseph Vyankandondera, Robert Pool, John Ruhirimbura, Chantal Kanakuze, Peter Reiss, Sibyl Geelen, Janneke van de Wijgert, Kimberly R Boer

“…Forty-two HIV positive adolescents (ages 12-21) and a selection of their primary caregivers were interviewed. All were perinatally-infected and received (cART) for ≥ 12 months. …”
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Is universal HBV vaccination of healthcare workers a relevant strategy in developing endemic countries? The case of a university hospital in Niger. by Gérard Pellissier, Yazdan Yazdanpanah, Eric Adehossi, William Tosini, Boubacar Madougou, Kaza Ibrahima, Isabelle Lolom, Sylvie Legac, Elisabeth Rouveix, Karen Champenois, Christian Rabaud, Elisabeth Bouvet

“…However, the high rate of natural immunization among adults in such countries where most infections occur perinatally or during early childhood must be taken into account. …”
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Low-cost HIV-1 diagnosis and quantification in dried blood spots by real time PCR. by Nishaki Mehta, Sonia Trzmielina, Bareng A S Nonyane, Melissa N Eliot, Rongheng Lin, Andrea S Foulkes, Kristina McNeal, Arthur Ammann, Vindu Eulalievyolo, John L Sullivan, Katherine Luzuriaga, Mohan Somasundaran

“…Recent recommendations to treat perinatally infected infants within the first year of life are feasible only if early diagnosis is routinely available. …”
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Successful tactile based visual sensory substitution use functions independently of visual pathway integrity by Vincent eLee, Amy Catherine Nau, Charles eLaymon, Kevin eChan, Beda eRosario, Chris eFisher

“…Purpose: We explored the microstructural differences between perinatally blind (PB), acquired blind (AB), and normally sighted controls (SC) and related these differences to performance on functional tasks using a sensory substitution device (BrainPort). …”
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CD4+ cell count recovery following initiation of HIV antiretroviral therapy in older childhood and adolescence by Simms, V, Rylance, S, Bandason, T, Dauya, E, McHugh, G, Munyati, S, Mujuru, H, Rowland-Jones, S, Weiss, H, Ferrand, R

“… <h4>Objective</h4> <p>To investigate CD4þ cell count recovery following ART initiation in perinatally HIV-infected children diagnosed in later childhood.…”

A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation. by Esapa, C, Hough, T, Testori, S, Head, R, Crane, E, Chan, C, Evans, H, Bassett, J, Tylzanowski, P, McNally, E, Carr, A, Boyde, A, Howell, P, Clark, A, Williams, G, Brown, M, Croucher, P, Nesbit, M, Brown, S, Cox, R, Cheeseman, M, Thakker, R

“…Lpk/+ mice were viable and fertile and Lpk/Lpk mice died perinatally. Lpk was mapped to chromosome 15 and mutational analysis of likely candidates from the interval revealed a Col2a1 missense Ser1386Pro mutation. …”

How mothers feel: validation of a measure of maternal mood by McGlynn, ES, Martin, CR, Redshaw, M

“…Early identification of mood disturbance is crucial to improve outcomes for women perinatally. Instruments such as the Edinburgh Postnatal Depression Scale (EPDS) are used routinely, with evidence that some women do not feel comfortable with how they are asked about their mental health.…”

Impact of host restriction factors and capsid evolution on HIV disease progression by Boswell, M

“…In chapter three we discuss the effect of <em>TRIM</em> genotype on disease outcomes in children and adolescents infected perinatally with HIV-1. We characterised TRIM genetic diversity in this cohort and found that TRIM22 genotype is associated with CD4⁺ T cell counts and, potentially, disease progression rates. …”

History of tuberculosis is associated with lower exhaled nitric oxide levels in HIV-infected children by Sovershaeva, E, Kranzer, K, McHugh, G, Bandason, T, Majonga, ED, Usmani, OS, Rowland-Jones, S, Gutteberg, T, Flægstad, T, Ferrand, RA, Odland, JØ

“…We investigated the relationship between exhaled nitric oxide (eNO), HIV status and airway abnormalities in perinatally HIV-infected children aged 6-19 years. DESIGN:A cross-sectional study.…”

Access, timeliness and retention for HIV testing under early infant diagnosis (EID) program, India by Suchit Kamble, Nilesh Gawde, Noopur Goel, Mohan Thorwat, Kalyani Nikhare, Shilpa Bembalkar, Sushmita Kamble, Radhika Brahme, Swapna Pawar, Rakesh Sahoo, Manish Rana, Manishkumar Singh, Syed Ahmed Mohiuddin, Shivappa Hatnoor, Bayapa Reddy Narapureddy, M. Saleem, Kirti Shekhawat, Vinita Verma, Neha Kapoor, Chinmoyee Das, Raman Gangakhedkar

“…Abstract Early Infant Diagnosis of HIV infection services are crucial for managing the perinatally acquired HIV infection. Assessing the performance of the EID services and its underlying determinants is important for the National AIDS Control Program, India. …”
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Activation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis by Eva Svandova, Eva Svandova, Barbora Vesela, Barbora Vesela, Abigail S. Tucker, Eva Matalova, Eva Matalova

“…In the adjacent bone, active caspases-7 and -8 were present abundantly in the prenatal period, while the appearance of caspases-3,-6, and -9 was marginal. Perinatally, caspases-3 and -7 were evident in some osteoclasts and osteoblastic cells, and caspase-8 was abundant mostly in osteoclasts. …”
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Association of umbilical cord serum TARC/CCL17 with childhood allergies: A birth cohort study by Noriko Sato, Fumiya Yamaide, Taiji Nakano, Syuji Yonekura, Yoshitaka Okamoto, Naoki Shimojo

“…We collected 263 pairs of maternal and child cord blood samples perinatally and child blood samples at ages 1, 2, and 5 years. …”
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Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression by Avinash V. Dharmadhikari, Jenny J. Sun, Krzysztof Gogolewski, Brandi L. Carofino, Vladimir Ustiyan, Misty Hill, Tadeusz Majewski, Przemyslaw Szafranski, Monica J. Justice, Russell S. Ray, Mary E. Dickinson, Vladimir V. Kalinichenko, Anna Gambin, Paweł Stankiewicz

“…Thirty-five percent of heterozygous R26-Lox-Stop-Lox (LSL)-Foxf1 embryonic day (E)15.5 embryos exhibit subcutaneous edema, hemorrhages and die perinatally when bred to Tie2-cre mice, which targets Foxf1 overexpression to endothelial and hematopoietic cells. …”
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Neuromodulation and antenatal depression: a&nbsp;review by Kim DR, Snell JL, Ewing GC, O’Reardon J

“…Keywords: electroconvulsive therapy, transcranial magnetic stimulation, pregnancy, depression, antenatal depression, perinatal…”
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A cost-effective melting temperature assay for the detection of single-nucleotide polymorphism in the MBL2 gene of HIV-1-infected children by Arraes L.C., de Souza P.R., Bruneska D., Castelo Filho A., de Souza Cavada B., de Lima Filho J.L., Crovella S.

“…Our data confirm the association between the presence of the mutated MBL2 allele (allele 0) and HIV-1 infection in perinatally exposed children. Our results are in agreement with the literature data which indicate that the presence of the allele 0 confers a relative risk of 1.37 for HIV-1 infection through vertical transmission.…”
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Acute development of Cushing syndrome in an HIV-infected child on atazanavir/ritonavir based antiretroviral therapy by Gueorgui Dubrocq, Andrea Estrada, Shannon Kelly, Natella Rakhmanina

“…An 11-year-old male with perinatally acquired human immune deficiency virus (HIV) infection on antiretroviral regimen, which included abacavir plus lamivudine (Epzicom), didanosine, ritonavir and atazanavir presented with bilateral axillary striae, increased appetite, fatigue, facial swelling and acute weight gain. …”
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Differences in location of cerebral white matter hyperintensities in children and adults living with a treated HIV infection: A retrospective cohort comparison. by Jason G van Genderen, Malon Van den Hof, Anders C Boyd, Matthan W A Caan, Ferdinand W N M Wit, Peter Reiss, Dasja Pajkrt

“…As age and principal routes of transmission differ between children (perinatally) and adults (behaviorally), comparing the characteristics and determinants of WMH between these populations may increase our understanding of the pathophysiology of WMH. …”
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Higher retention and viral suppression with adolescent-focused HIV clinic in South Africa. by Brian C Zanoni, Thobekile Sibaya, Chelline Cairns, Sara Lammert, Jessica E Haberer

“…PARTICIPANTS:Two hundred forty-one perinatally HIV-infected adolescents and young adults aged 13 to 24 years attending an adolescent-friendly clinic or the standard pediatric clinic from April 2007 to November 2015. …”
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Microglial heterogeneity and complement component 3 elimination within emerging multisensory midbrain compartments during an early critical period by Julianne B. Carroll, Shaida Hamidi, Mark L. Gabriele

“…This arrangement emerges perinatally in mice (postnatal day, P0-P12) as somatosensory and auditory inputs segregate into their respective modular and matrix terminal patterns. …”
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