Implementing ecological momentary assessments to measure violence and adolescent HIV transmission risk: Lessons from Johannesburg, South Africa. by Janan Janine Dietrich, Stefanie Hornschuh, Phumla Madi, Candice W Ramsammy, Lerato Tsotetsi, Gugulethu Tshabalala, Busisiwe Nkala-Dlamini, Avy Violari, Rachel Kidman

“…The Tsamaisano study was a longitudinal study from 2020-2023 to recruit adolescent boys aged 15-19 years; including those without HIV and those perinatally infected and living with HIV. Participants were prompted to complete 52 weekly mobile phone survey on emotional state, exposure to and perpetration of violence, and sexual risk behaviour. …”
Get full text

Developmental Trajectory of Depressive Symptoms from Early Childhood through High School in Children and Adolescents with a High Intellectual Potential by Laurence Vaivre-Douret, Soukaina Hamdioui

“…The children’s parents completed a self-report questionnaire collected on different stages of the child’s school level, perinatality, psychomotor development, health, family’s history, behavior, interpersonal relationships and daily activities, school performance, presence of learning disorders and remediation. …”
Get full text

Entecavir Treatment in Children and Adolescents with Chronic Hepatitis B Virus Infection by Kai-Chi Chang, Jia-Feng Wu, Hong-Yuan Hsu, Huey-Ling Chen, Yen-Hsuan Ni, Mei-Hwei Chang

“…The aim of this study was to investigate the treatment response of entecavir (ETV) in children and adolescents with chronic hepatitis B (CHB) who acquired infection perinatally or during early childhood. Methods: A total of nine treatment-naïve patients [median aged 12.2 years (range: 2.6–18.0); five girls and four boys], with hepatitis B e antigen (HBeAg) seropositive > 6 months, alanine aminotransferase (ALT) > 2 times of upper limit of normal value (30 IU/L), were enrolled for ETV therapy. …”
Get full text

Asymptomatic Infant Rib Fractures Are Primarily Non-abuse-Related and Should Not Be Used to Assess Physical Child Abuse by Martin J. C. van Gemert, Marianne Vlaming, Steven C. Gabaeff, Peter G. J. Nikkels, H. A. Martino Neumann

“…In conclusion, occult asymptomatic rib fractures develop perinatally, virtually always as birth trauma, in infants with sufficiently weak bones due to vitamin D deficiency, transmitted by their vitamin D deficient pregnant mothers. …”
Get full text

Assessment of the HBV vaccine response in a group of HIV-infected children in Morocco by Houda Haban, Soumia Benchekroun, Mina Sadeq, Abdelaziz Benjouad, Said Amzazi, Hicham Oumzil, Elmir Elharti

“…Seroprotection titer i.e. anti-HBs ≥10mUI/ml among control group was 76% (85/112), and only 29% (14/49) among the perinatally HIV-infected children (p < 0.0001). Lower % of CD4 + T cells was observed in HIV-infected children with a poor anti-HBs response. …”
Get full text

Prevalence of physical and sexual violence and psychological abuse among adolescents and young adults living with HIV in Zambia. by Katherine G Merrill, Jacquelyn C Campbell, Michele R Decker, John McGready, Virginia M Burke, Jonathan K Mwansa, Sam Miti, Christiana Frimpong, Caitlin E Kennedy, Julie A Denison

“…<h4>Methods</h4>We analyzed baseline data from 272 AYA (60.1% female, 71.0% perinatally infected) enrolled in Project YES! (Youth Engaging for Success), a randomized controlled trial conducted in four HIV clinics in Ndola, Zambia. …”
Get full text

Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants. by Prendergast, A, Mphatswe, W, Tudor-Williams, G, Rakgotho, M, Pillay, V, Thobakgale, C, McCarthy, N, Morris, L, Walker, B, Goulder, P

“…OBJECTIVES: Infants infected with HIV-1 perinatally despite single-dose nevirapine progress rapidly. …”

Screening and supporting through schools: educational experiences and needs of adolescents living with HIV in a South African cohort by Toska, E, Cluver, L, Orkin, M, Bains, A, Sherr, L, Berezin, M, Gulaid, L

“…Slow progressors–adolescents infected perinatally who survive without access to lifesaving treatment–remain unidentified and disconnected from heath systems, especially in high-prevalence settings. …”

Doppler Spectral Wave Patterns of Ductus Venosus: Do they Change with Foetal Position in the First Trimester? by Harshavardan, V Ram Sanjith, SC Sanjay, Srinivas Shentar

Get full text

A longitudinal and qualitative analysis of caregiver depression and quality of life in the Cape Town adolescent antiretroviral cohort by Tatum Sevenoaks, Jean-Paul Fouche, Bulelwa Mtukushe, Nicole Phillips, Sarah Heany, Landon Myer, Heather J. Zar, Dan J. Stein, Jacqueline Hoare

“…Background: This study aimed to investigate depression and quality of life longitudinally in caregivers of adolescents with perinatally acquired HIV (PHIV) enrolled in the Cape Town Adolescent Antiretroviral Cohort (CTAAC). …”
Get full text

Immunogenicity of the Conjugate Meningococcal ACWY-TT Vaccine in Children and Adolescents Living with HIV by Arantxa Berzosa, Sara Guillen, Cristina Epalza, Luis Escosa, Maria Luisa Navarro, Luis M. Prieto, Talía Sainz, Santiago Jimenez de Ory, Marina Montes, Raquel Abad, Julio A. Vázquez, Irene Serrano García, José Tomás Ramos-Amador

“…Results: There were 29 CALHIV included, 76% of whom were perinatally infected. All were receiving TAR and presented a good immunovirological and clinical status overall. …”
Get full text

Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis by Annelies L. Robijn, Marleen P. Bokern, Megan E. Jensen, Daniel Barker, Katherine J. Baines, Vanessa E. Murphy

“…Methods Electronic databases were searched for the following terms: (asthma or wheeze) and (pregnan* or perinat* or obstet*) and (exacerb* or flare up or morbidit* or attack*). …”
Get full text

Viral suppression and adherence among HIV‐infected children and adolescents on antiretroviral therapy: results of a multicenter study by Maria L.S. Cruz, Claudete A.A. Cardoso, Mariana Q. Darmont, Edvaldo Souza, Solange D. Andrade, Marcia M. D’Al Fabbro, Rosana Fonseca, Jaime G. Bellido, Simone S. Monteiro, Francisco I. Bastos

“…Objective: To evaluate treatment adherence among perinatally‐infected pediatric human immunodeficiency virus (HIV) patients followed in pediatric centers in Brazil. …”
Get full text

Incidence of congenital toxoplasmosis among infants born to HIV-coinfected mothers: case series and literature review by Flávia Alves Campos, Gláucia Manzan Queiroz de Andrade, Antônio de Pádua Santos Lanna, Bruno Freitas Lage, Maria Vitória Mourão Assumpção, Jorge A. Pinto

“…Objective: To evaluate aspects of the mother–infant pairs associated with vertical transmission of toxoplasmosis in women co-infected with HIV in a referral center for perinatally acquired infections in Belo Horizonte, Brazil. …”
Get full text

Identification of a Potential Vaccine against <i>Treponema pallidum</i> Using Subtractive Proteomics and Reverse-Vaccinology Approaches by Siyab Khan, Muhammad Rizwan, Adnan Zeb, Muhammad Alaa Eldeen, Said Hassan, Ashfaq Ur Rehman, Refaat A. Eid, Mohamed Samir A. Zaki, Ghadeer M. Albadrani, Ahmed E. Altyar, Nehal Ahmed Talaat Nouh, Mohamed M. Abdel-Daim, Amin Ullah

“…It can be transmitted both sexually and perinatally. Since syphilis is the second most fatal sexually transmitted disease after AIDS, an efficient vaccine candidate is needed to establish long-term protection against infections by <i>T. pallidum.…”
Get full text

Impact of the 1st Wave of the COVID-19 Pandemic and Lockdown on In Utero Transfer Activity in the Paris Area, France by Alexandre J. Vivanti, Stanislas Fesquet, Diane Gabriel, Alexandra Letourneau, Catherine Crenn-Hebert, Daniele De Luca, Jean Bouyer, Sophie Novelli, Alexandra Benachi, Raphaël Veil

Get full text

Screening and supporting through schools: educational experiences and needs of adolescents living with HIV in a South African cohort by Elona Toska, Lucie Cluver, Mark Orkin, Anurita Bains, Lorraine Sherr, McKenzie Berezin, Laurie Gulaid

“…Slow progressors–adolescents infected perinatally who survive without access to lifesaving treatment–remain unidentified and disconnected from heath systems, especially in high-prevalence settings. …”
Get full text

HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study. by Willy Le Roi Togna Pabo, Joseph Fokam, Debimeh Njume, Désiré Takou, Maria-Mercedes Santoro, Raymond Babila Nyasa, Collins Chenwi, Marie Laure Mpouel, Grace Beloumou, Ezechiel Semengue Ngoufack Jagni, Alex Durand Nka, Aude Christelle Ka'e, Georges Teto, Beatrice Dambaya, Sandrine Djupsa, Davy Hyacinthe Gouissi Anguechia, Molimbou Evariste, Cedric Kamta, Lionel Bala, Virginie Lambo, Edie Gregory Halle-Ekane, Vittorio Colizzi, Carlo Federico Perno, Alexis Ndjolo, Roland Ndip Ndip

“…<h4>Objective</h4>We sought to evaluate the variability of HIV-1 and its effect on immuno-virological response among adolescents living with perinatally acquired HIV (APHI).<h4>Methods</h4>A cohort study was conducted from 2018-2020 among 311 APHI receiving antiretroviral therapy (ART) in Cameroon. …”
Get full text

Functional analysis of cancer-causing FBXW7 mutations by Davis, HL

“…</p><p>This propellor-tip mutation was knocked-in constitutively and whilst heterozygous mice developed normally in utero, they died perinatally due to defective lung development. Cleft palate and eyelid fusion defects were also observed with incomplete penetrance. …”

Chitinase-3-like Protein 1 Is Associated with Poor Virologic Control and Immune Activation in Children Living with HIV by Isabelle Bernard, Doris G. Ransy, Jason Brophy, Fatima Kakkar, Ari Bitnun, Lindy Samson, Stanley Read, Hugo Soudeyns, Michael T. Hawkes, EPIC⁴ Study Group

“…Perinatally infected children living with HIV (CLWH) face lifelong infection and associated inflammatory injury. …”
Get full text