Un-biased housekeeping gene panel selection for high-validity gene expression analysis by Ana I. Casas, Ahmed A. Hassan, Quirin Manz, Christian Wiwie, Pamela Kleikers, Javier Egea, Manuela G. López, Markus List, Jan Baumbach, Harald H. H. W. Schmidt

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scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases by Samuel Schäfer, Martin Smelik, Oleg Sysoev, Yelin Zhao, Desiré Eklund, Sandra Lilja, Mika Gustafsson, Holger Heyn, Antonio Julia, István A. Kovács, Joseph Loscalzo, Sara Marsal, Huan Zhang, Xinxiu Li, Danuta Gawel, Hui Wang, Mikael Benson

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Dynamic survival prediction of end-stage kidney disease using random survival forests for competing risk analysis by Daniel Christiadi, Daniel Christiadi, Daniel Christiadi, Kevin Chai, Aaron Chuah, Bronwyn Loong, Thomas D. Andrews, Aron Chakera, Giles Desmond Walters, Giles Desmond Walters, Giles Desmond Walters, Simon Hee-Tang Jiang, Simon Hee-Tang Jiang, Simon Hee-Tang Jiang

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Extracellular Vesicles in Amyotrophic Lateral Sclerosis by Gavin McCluskey, Karen E. Morrison, Colette Donaghy, Frederique Rene, William Duddy, Stephanie Duguez

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Chronic periodontitis, dantamoolaroga, indicates chronic systemic inflammation and reduces longevity by Graeme Stringer

“…It is found that oral health reflects systemic health and provides a window into general health. As personalised medicine is being developed to assess the multiple pathophysiological factors underlying systemic chronic inflammation, it is noted that Ayurveda has a comprehensive approach to diagnosis with the 10 fold assessment (Dashavidha Praiksha) and eight fold examinations (Astasthana Pariksha) being considered the original personalised medicine. …”
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The Challenges of Local Intra-Articular Therapy by Gailute Kirdaite, Jaroslav Denkovskij, Diana Mieliauskaite, Jolita Pachaleva, Eiva Bernotiene

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Stakeholder-led understanding of the implementation of digital technologies within heart disease diagnosis: a qualitative study protocol by Faith Matcham, Kamilla Abdullayev, Matthew Manktelow, Oliver Buckley, Joan Condell, Richard J Van Arkel, Timothy JA Chico, Vanessa Diaz

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Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives by Niclas Skarne, Rochelle C. J. D’Souza, Helen M. Palethorpe, Kylah A. Bradbrook, Guillermo A. Gomez, Bryan W. Day

“…GBOs currently hold significant promise, with the potential to emerge as the key translational tool to synergise and enhance next-generation omics efforts and guide personalised medicine approaches for brain cancer patients into the future.…”
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A perspective for sequencing familial hypercholesterolaemia in African Americans by Wright, Michelle L, Taylor, Jacquelyn Y, Housman, David E

“…The purpose of this paper is to provide a perspective, using familial hypercholesterolaemia as an exemplar, that studies evaluating genetic variation focused within minority populations are necessary to identify factors that contribute to disparities in health outcomes and realise the full utility of personalised medicine.…”
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HbA1c for type 2 diabetes diagnosis in Africans and African Americans: Personalized medicine NOW! by Andrew D Paterson

“…Andrew Paterson discusses findings from a new study that shows HbA1c screening for diabetes will leave 2% of African Americans undiagnosed and how personalised medicine is needed.…”
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The Convergence of Nanotechnology, Biotechnology and Cancer Medicine in the Fourth Industrial Revolution by Zamanzima Mazibuko and Steven Mufamadi

“…Medical technologies of the fourth industrial revolution (Industry 4.0), such as nanotechnology, biotechnology, artificial intelligence (AI), 3D printing and advanced materials are already transforming medical technology and the pharmaceutical industry by offering accurate diagnoses, targeting therapies with fewer side effects, and providing better medical imaging and personalised medicine.…”
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The Convergence of Nanotechnology, Biotechnology and Cancer Medicine in the Fourth Industrial Revolution by Steven Mufamadi, Zamanzima Mazibuko

“… Medical technologies of the fourth industrial revolution (Industry 4.0), such as nanotechnology, biotechnology, artificial  intelligence (AI), 3D printing and advanced materials are already transforming medical technology and the pharmaceutical industry by offering accurate diagnoses, targeting therapies with fewer side effects, and providing better medical imaging and personalised medicine. …”
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Profiling of Somatic Mutations in Phaeochromocytoma and Paraganglioma by Targeted Next Generation Sequencing Analysis by Andrea Luchetti, Diana Walsh, Fay Rodger, Graeme Clark, Tom Martin, Richard Irving, Mario Sanna, Masahiro Yao, Mercedes Robledo, Hartmut P. H. Neumann, Emma R. Woodward, Farida Latif, Stephen Abbs, Howard Martin, Eamonn R. Maher

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A meta-analysis of the use of intraoperative cholangiography; time to revisit our approach to cholecystectomy? by Eoin Donnellan, Medical student, Jonathan Coulter, Specialist Surgical Registrar (BM BS BSc MRCSI), Cherian Mathew, Medical student, Michelle Choynowski, Doctor (BSc MB BCh BAO), Louise Flanagan, Registered Nurse (BSc), Magda Bucholc, PhD, Lecturer in Data Analytics, Alison Johnston, Specialist Breast Care Nurse (MSc), Michael Sugrue, Consultant Surgeon (MB BCh BAO MD FRSCI FRACS)

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Genomic testing in international guidelines by Peter Kern, Mahdi Rezai, Christian Singer, Rainer Kimmig

“…It seems that North America and some European countries have initiated a shift towards a personalised medicine with multigene arrays based on RT-PCR or microarrays.…”
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Global research in schizophrenia and serotonin: a bibliometric analysis by Gustavo Canul-Medina, Gael López-Pech, Francisco Jiménez-Trejo

“…Future schizophrenia and serotonin research is likely to focus on personalised medicine, alternative therapies, novel pathogenesis of schizophrenia, and the use of emerging technologies such as artificial intelligence.…”
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Artificial Intelligence for Clinical Prediction: Exploring Key Domains and Essential Functions by Mohamed Khalifa, Mona Albadawy

“…Discussion: The review highlights AI's transformative impact across various clinical prediction domains, including its role in revolutionising diagnostics, improving prognosis accuracy, aiding in personalised medicine, and enhancing patient safety. AI-driven tools contribute significantly to the efficiency and effectiveness of healthcare delivery. …”
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Ethical issues raised by new genomic technologies: the case study of newborn genome screening by Rachel Horton, Anneke Lucassen

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What have we learnt from the inhibition of IL-6 in RA and what are the clinical opportunities for patient outcomes? by Peter C. Taylor, Eugen Feist, Janet E. Pope, Peter Nash, Jean Sibilia, Roberto Caporali, Alejandro Balsa

“…This review explores the role of IL-6 in RA pathogenesis, its potential as a treatment target and the significance of personalised medicine in RA management. IL-6 has a dual signalling mechanism, classical and trans-signalling, which influences various intracellular pathways. …”
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Stakeholder perspectives on contributors to delayed and inaccurate diagnosis of cardiovascular disease and their implications for digital health technologies: a UK-based qualitativ... by Faith Matcham, Timothy Chico, Kamilla Abdullayev, Olivia Gorvett, Anna Sochiera, Matthew Manktelow, Oliver Buckley, Joan Condell, Vanessa Diaz, Lynn Laidlaw, Richard Van Arkel

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