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421
3D Printing of Pharmaceuticals and Drug Delivery Devices
Published 2020-03-01“…This novel method allows the manufacture of dosage forms on demand, with modifications in the geometry and size resulting in changes to the release and dosage behaviour of the product. 3DP will allow wider adoption of personalised medicine due to the diversity and simplicity to change the design and dosage of the products, allowing the devices to be designed specific to the individual with the ability to alternate the drugs added to the product. …”
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422
Engineering requirements of a herpes simplex virus patient registry: discovery phase of a real-world evidence platform to advance pharmacogenomics and personalized medicine
Published 2019“…Through the analysis of the current state of the art and thematic user analysis, potential design features were elucidated to facilitate the collection of high-quality, robust patient-level data which could contribute to advances in pharmacogenomic understanding and personalised medicine in HSV. The user requirements specification for the development of an HSV registry has been summarised and implementation strategies for the alpha phase discussed.…”
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423
An overview of image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities
Published 2022-01-01“…Mass spectrometry imaging (MSI) is used in many aspects of clinical research, including pharmacokinetics, toxicology, personalised medicine, and surgical decision-making. Maximising its potential requires the spatial integration of MSI images with imaging data from existing clinical imaging modalities, such as histology and MRI. …”
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424
A "crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals.
Published 2012-01-01“…CONCLUSIONS/SIGNIFICANCE: Our study shows that the intra-individual variability was at least two-fold lower compared to the inter-individual one at all investigated levels, showing the importance of personalised medicine approach from yet another perspective.…”
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425
Drug development for the irritable bowel syndrome: current challenges and future perspectives
Published 2013-02-01“…d) in the era of personalised medicine, does pharmacogenomics applied to these medications already play a role? …”
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426
3D Printed Organs: The Future of Regenerative Medicine
Published 2019-11-01“…The 3D printed organs have the potential to bring an era of personalised medicine as 3D printed organs can relieve the burden of organ transplants and donors. …”
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427
Putative protective genomic variation in the Lithuanian population
Published 2024-04-01“…Identification of effect variants is a step towards better understanding of the microevolutionary processes, etiopathogenetic mechanisms, and personalised medicine.…”
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428
Suicide risk assessment tools and prediction models: new evidence, methodological innovations, outdated criticisms
Published 2024-03-01“…These models aim to assist in stratifying risk, improve clinical decision-making, and facilitate a personalised medicine approach to the prevention of suicidal behaviour. …”
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429
In Search of Complex Disease Risk through Genome Wide Association Studies
Published 2021-11-01“…The generation of catalogues of genetic variants that have an impact on specific diseases is the basis of Personalised Medicine, where diagnoses and treatment protocols are selected according to each patient’s profile. …”
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430
Toward Morphologic Atlasing of the Human Whole Brain at the Nanoscale
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431
Biomarker-guided trials: Challenges in practice
Published 2019-12-01“…Keywords: Clinical trial, Biomarker, Challenges, Personalised medicine…”
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432
Extracellular Vesicles in Comorbidities Associated with Ischaemic Heart Disease: Focus on Sex, an Overlooked Factor
Published 2021-01-01“…This implies that early diagnosis and personalised medicine, also related to sex differences, are mandatory for primary or secondary prevention. …”
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433
Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak
Published 2020-09-01“…This review discusses the past success in drug repositioning, the current technological advancement in the field, drug repositioning for personalised medicine and the ongoing research on newly emerging drugs under consideration for the COVID-19 treatment.…”
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434
DOCTOR'S PROFESSIONAL COMPETENCES IN TELEMEDICINE
Published 2021-09-01“…Conclusion: Telemedicine and personalised medicine in Russia and globally are opening up a new frontier for the medical industry development. …”
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435
Thrombin generation - a potentially useful biomarker of thrombotic risk in Philadelphia-negative myeloproliferative neoplasms
Published 2017-03-01“…The currend trend to personalised medicine requires finding the most useful thrombotic risk biomarker in these patients. …”
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436
The chemical tool-kit for molecular imaging with radionuclides in the age of targeted and immune therapy
Published 2021-01-01“…These radiochemical innovations have been inspired by the need to support personalised medicine and also by the parallel development in development of new radionuclide imaging technologies – from gamma scintigraphy, through single photon emission tomography (SPECT), through the rise of clinical positron emission tomography (PET) and PET-CT, and perhaps in the future, by the advent of total body PET. …”
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437
Impact of Diet on Symptoms of the Irritable Bowel Syndrome
Published 2021-02-01“…More research is needed to fully understand the mechanisms of food intolerances and how to best ameliorate them in a personalised medicine approach to diet in IBS.…”
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438
Artificial Intelligence and Its Role In The Development Of Personalized Medicine And Drug Control
Published 2022-12-01“…AI can play a significant role in the clinical research and development of new personalised health products, from selecting relevant contribute to sustainable to testing their utility, because of the importance of data-intensive assays in revealing appropriate intervention objectives and approaches for personalising medicines. The work here presents a variety of ways in which AI can contribute to the progress of personalised medicine, and we argue that the success of this endeavour is critically dependent on the improvement of appropriate assays and methods for storing, aggregating, accessing, and ultimately combining the data they generate. …”
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439
Therapeutic dosing of acenocoumarol: proposal of a population specific pharmacogenetic dosing algorithm and its validation in north Indians.
Published 2012-01-01“…CONCLUSIONS: We have proposed an efficient north India specific pharmacogenetic acenocoumarol dosing algorithm which might become a baseline for personalised medicine approach for treatment of patients in future.…”
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440
Public trust and global biobank networks
Published 2020-08-01“…Abstract Background Biobanks provide an important foundation for genomic and personalised medicine. In order to enhance their scientific power and scope, they are increasingly becoming part of national or international networks. …”
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