Exploring treatment by covariate interactions using subgroup analysis and meta-regression in cochrane reviews: a review of recent practice. by Sarah Donegan, Lisa Williams, Sofia Dias, Catrin Tudur-Smith, Nicky Welton

“…Such analyses can provide information on how the covariate modifies the treatment effect and is an important methodological approach for personalising medicine. Guidance exists regarding how to apply such analyses but little is known about whether authors follow the guidance.Using published recommendations, we developed criteria to assess how well interaction analyses were designed, applied, interpreted, and reported. …”
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I Spy with My Little Eye: A Paediatric Visual Preferences Survey of 3D Printed Tablets by Patricija Januskaite, Xiaoyan Xu, Sejal R. Ranmal, Simon Gaisford, Abdul W. Basit, Catherine Tuleu, Alvaro Goyanes

“…3D printing (3DP) in the pharmaceutical field is a disruptive technology that allows the preparation of personalised medicines at the point of dispensing. The paediatric population presents a variety of pharmaceutical formulation challenges such as dose flexibility, patient compliance, taste masking and the fear or difficulty to swallow tablets, all factors that could be overcome using the adaptable nature of 3DP. …”
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Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies. by Michael V Holmes, Tina Shah, Christine Vickery, Liam Smeeth, Aroon D Hingorani, Juan P Casas

“…Recommendations based on these findings should inform future study design to help realise the goal of personalised medicines. SYSTEMATIC REVIEW REGISTRATION NUMBER: Not Registered.…”
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