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The History of Pertussis Toxin
Published 2021-09-01“…In this article, we review the history of pertussis toxin, including the paradigm shift that occurred in the 1980s which established the pertussis toxin as a single molecule. …”
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Novel Strategies to Inhibit Pertussis Toxin
Published 2022-03-01Subjects: “…pertussis toxin…”
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Intracellular Trafficking and Translocation of Pertussis Toxin
Published 2019-07-01“…Pertussis toxin (PT) is a multimeric complex of six proteins. …”
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Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin
Published 2019-05-01Subjects: “…genetically detoxified pertussis toxin…”
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Pertussis Toxin: A Key Component in Pertussis Vaccines?
Published 2019-09-01Subjects: Get full text
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Pertussis, anti-Bordetella pertussis toxin, vaccination, and clinical surveillance
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Secretion of Pertussis Toxin from <i>Bordetella pertussis</i>
Published 2021-08-01Subjects: Get full text
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Assays for Determining Pertussis Toxin Activity in Acellular Pertussis Vaccines
Published 2019-07-01Subjects: “…pertussis toxin…”
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Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection
Published 2023-12-01Subjects: Get full text
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Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin
Published 2021-07-01Subjects: “…pertussis toxin…”
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Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin
Published 2018-05-01Subjects: “…pertussis toxin…”
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Orexin Receptor Type-1 Couples Exclusively to Pertussis Toxin-Insensitive G-Proteins, While Orexin Receptor Type-2 Couples to Both Pertussis Toxin-Sensitive and -Insensitive G-Proteins
Published 2003-01-01“…Forskolin-stimulated cyclic adenosine 3,5-monophosphate (cAMP) accumulation in OX2R-expressing cells was inhibited by orexin in a dose-dependent manner, and the effect was abolished by pretreatment with pertussis toxin (PTX). The inhibitory effect of orexin on forskolin-stimulated cAMP accumulation was not observed in OX1R-expressing cells. …”
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Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action
Published 2023-06-01Subjects: “…pertussis toxin…”
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<i>In Vivo</i> Models and <i>In Vitro</i> Assays for the Assessment of Pertussis Toxin Activity
Published 2021-08-01Subjects: “…pertussis toxin…”
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Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis
Published 2021-01-01“…Serological diagnosis of pertussis is mainly based on anti-pertussis toxin (PT) IgG antibodies. Since PT is included in all acellular vaccines (ACV), serological assays do not differentiate antibodies induced by ACVs and infection. …”
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A novel vaccine formulation candidate based on lipooligosaccharides and pertussis toxin against Bordetella pertussis
Published 2023-04-01Subjects: Get full text
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cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin.
Published 2008“…The enzymatic activity of the three most studied bacterial toxins that increase the cytosolic cAMP level: pertussis toxin (PT), cholera toxin (CT), and anthrax edema toxin (ET), was imaged by fluorescence videomicroscopy. …”
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Repetitive pertussis toxin promotes development of regulatory T cells and prevents central nervous system autoimmune disease.
Published 2010-12-01“…Incidence and severity of its animal model experimental autoimmune encephalomyelitis (EAE) can be enhanced by concomitant administration of pertussis toxin (PTx), the major virulence factor of Bordetella pertussis. …”
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The CHO Cell Clustering Response to Pertussis Toxin: History of Its Discovery and Recent Developments in Its Use
Published 2021-11-01Subjects: Get full text
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