Shedding light on restoring respiratory function after spinal cord injury by Warren J Alilain, Jerry Silver

“…Because of this, much work has been done in studying ways to restore respiratory function following SCI - including pharmacological and regeneration strategies. With the emergence of new and powerful tools from molecular neuroscience, new therapeutically relevant alternatives to these approaches have become available, including expression of light sensitive proteins called channelrhodopsins. …”
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Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation by Amy Q. Lu, Evgenya Y. Popova, Colin J. Barnstable

“…The effect of activin on CRX expression was repressed by pharmacological inhibition of SMAD2/3 phosphorylation. …”
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Fabrication and characterization of salidroside W/O/W emulsion with sodium alginate by Qian Zhang, Yu-Qiao Wang, Lin Li, Hao-Lin Song, Hai-Tao Wu, Bei-Wei Zhu

“…Salidroside (Sal), the main bioactive substance in Rhodiola rosea, is a promising functional food component with a wide range of pharmacological effects, but its biological activity is challenging to sustain due to its short half-life, low oral bioavailability, and susceptibility to environmental factors. …”
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Nursing diagnosis “nausea” during chemotherapy: concept analysis by Aline Maria Bonini Moysés, Ana Maria de Almeida, Lais Corsino Durant, Thais de Oliveira Gozzo

“…Thirty articles composed the sample, we identified 44 antecedents, being 25 related to the patient/biophysical, eight to the treatment/pharmacological factors and, 11 related to psychological factors. …”
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Primary Hyperparathyroidism in Patients with Multiple Endocrine Neoplasia Type 1 by Grzegorz Piecha, Jerzy Chudek, Andrzej Więcek

“…It also summarises the recent advances in the pharmacological therapy with a new group of drugs—calcimimetics.…”
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Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies by Fei Wang, Gabriele Multhoff

“…In recent years, evidence has accumulated that cannabinoids—especially the non-psychoactive compound, cannabidiol (CBD)—possess promising medical and pharmacological activities that might qualify them as potential anti-tumor drugs. …”
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Thyroid storm in pregnancy: a review by Vidhu Vadini, Prabhav Vasistha, Almog Shalit, Spyridoula Maraka

“…Treatment involves specialist consultation, supportive care, and pharmacological options such as anti-thyroid medications, beta blockers, iodine solutions, glucocorticoids, and cholestyramine. …”
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Aptamers as an approach to targeted cancer therapy by Fatemeh Mahmoudian, Azin Ahmari, Shiva Shabani, Bahman Sadeghi, Shohreh Fahimirad, Fahimeh Fattahi

“…They are typically produced through the systematic evolution of ligands by exponential enrichment (SELEX) and undergo extensive pharmacological revision to modify their affinity, specificity, and therapeutic half-life. …”
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Digitoxin and its analogs as novel cancer therapeutics by Elbaz Hosam A, Stueckle Todd A, Tse William, Rojanasakul Yon, Dinu Cerasela

“…Moreover, a new perspective on the pharmacological aspects of digitoxin and its analogs is provided to emphasize new research directions for developing potent chemotherapeutic drugs.…”
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Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health by Luigi Fontana, Nicole E. Cummings, Sebastian I. Arriola Apelo, Joshua C. Neuman, Ildiko Kasza, Brian A. Schmidt, Edda Cava, Francesco Spelta, Valeria Tosti, Faizan A. Syed, Emma L. Baar, Nicola Veronese, Sara E. Cottrell, Rachel J. Fenske, Beatrice Bertozzi, Harpreet K. Brar, Terri Pietka, Arnold D. Bullock, Robert S. Figenshau, Gerald L. Andriole, Matthew J. Merrins, Caroline M. Alexander, Michelle E. Kimple, Dudley W. Lamming

“…Our results highlight a critical role for dietary quality at the level of amino acids in the maintenance of metabolic health and suggest that diets specifically reduced in BCAAs, or pharmacological interventions in this pathway, may offer a translatable way to achieve many of the metabolic benefits of a PR diet.…”
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Phytochemical Profiles and Biological Activities of <i>Frankenia</i> Species: A Review by Meyada Khaled, Rachid Ouache, Patrick Pale, Hassina Harkat

“…To date, several studies on either phytochemical or pharmacological aspects, or both, have revealed that this genus is a rich source of diverse and novel bioactive chemicals, including phenolics, flavonoids, alkaloids and fatty acids. …”
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Impaired muscarinic modulation of the rat prelimbic cortex in neuropathic pain is sexually dimorphic and associated with cold allodynia by Taylor Jefferson, Haram R. Kim, Marco Martina

“…Finally, we found that selective pharmacological blockade of the muscarinic M1 subunit in the prefrontal cortex induces cold sensitivity (but not mechanical allodynia) in naïve animals of both sexes.…”
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A Case with Improvement of Blepharospasm by Zolpidem by Munkyung Sunwoo, Junghee Cho, Jun Hong Lee, Gyu Sik Kim, Jong Hun Kim, Sun-Ah Choi

“…Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Further randomized, blinded, placebo-controlled studies are needed to validate this finding.…”
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Effect of quercetin on the progression of breast cancer in mice with chronic stress by regulating the polarization of microglia by Tianyu Luo, Yuqi Liang, Liushan Chen, Haidong Sun, Qianjun Chen

“…Quercetin is a bioactive flavonoid with a wide range of pharmacological effects. This study explores the effect and mechanism of quercetin on microglia in the treatment of chronic stress breast cancer. …”
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Redefining GERD management: The emerging role of potassium-competitive acid blockers by Vania Azalia Gunawan, Titong Sugihartono

“…Proton pump inhibitors (PPIs) are the primary pharmacologic therapy, but approximately 40% of patients remain symptomatic. …”
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Dietary Supplements and Sports Performance: Introduction and Vitamins by Williams Melvin H

“…However, athletes often attempt to go beyond training and use substances and techniques, often referred to as ergogenics, in attempts to gain a competitive advantage. Pharmacological agents, such as anabolic steroids and amphetamines, have been used in the past, but such practices by athletes have led to the establishment of anti-doping legislation and effective testing protocols to help deter their use. …”
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Training methods for high-altitude acclimatization and its applications in military by WANG Yongchun, LI Jiaxiang

“…Additionally， non-pharmacological strategies such as intermittent hypoxia and pre-simulated altitude training have also been proven to effectively promote altitude acclimatization. …”
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Neuroinflammation Treatment via Targeted Delivery of Nanoparticles by Susana R. Cerqueira, Susana R. Cerqueira, Nagi G. Ayad, Nagi G. Ayad, Nagi G. Ayad, Jae K. Lee, Jae K. Lee

“…We propose that state-of-the-art nanoparticle drug delivery platforms can significantly impact local CNS bioavailability of pharmacological compounds and treat neurological diseases.…”
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Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role by Irina Giralt, Gabriel Gallo-Oller, Natalia Navarro, Patricia Zarzosa, Guillem Pons, Ainara Magdaleno, Miguel F. Segura, José Sánchez de Toledo, Lucas Moreno, Soledad Gallego, Josep Roma

“…Although there is growing information related to function and regulation of Dickkopf (DKK) proteins, their pharmacological potential as cancer therapeutics still has not been fully developed. …”
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Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer by Alessandro Parodi, Magdalena Rudzińska, Andrei A. Deviatkin, Surinder M. Soond, Alexey V. Baldin, Andrey A. Zamyatnin

“…Brain tumors are characterized by very high mortality and, despite the continuous research on new pharmacological interventions, little therapeutic progress has been made. …”
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