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Evolution of phenotypic diversity
Published 2023“…Phenotypic diversity, also known as phenotypic heterogeneity, occurs when individuals within a species have different phenotypes. …”
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Metabolic Phenotypes in Asthmatic Adults: Relationship with Inflammatory and Clinical Phenotypes and Prognostic Implications
Published 2021-08-01Subjects: Get full text
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Phenotypes Associated With MEN1 Syndrome: A Focus on Genotype-Phenotype Correlations
Published 2020-11-01Subjects: Get full text
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The Sherpa hypothesis: Phenotype-Preserving Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes
Published 2023-07-01“…Here, we introduce the Sherpa hypothesis, according to which a subset of stable IDPs that we term Phenotype-Preserving Disordered Proteins (PPDP) play a central role in protecting cell phenotypes from perturbations. …”
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Thinking of Fish Population Discrimination: Population Average Phenotype vs. Population Phenotypes
Published 2021-10-01“…The genetic polymorphism and phenotypic variation are key in ecology and evolution. …”
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Clinical variability of equine asthma phenotypes and analysis of diagnostic steps in phenotype differentiation
Published 2024-09-01Subjects: Get full text
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Binary Metabolic Phenotypes and Phenotype Diversity Metrics for the Functional Characterization of Microbial Communities
Published 2021-05-01Subjects: Get full text
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Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.
Published 2013-01-01“…Macrophages (MΦ) play an essential role in innate immune responses and can either display a pro-inflammatory, classically activated phenotype (M1) or undergo an alternative activation program (M2) promoting immune regulation. …”
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A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping.
Published 2011-01-01“…The range of genotype-phenotype associations can be represented using the Mammalian Phenotype ontology. …”
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A novel method for multiple phenotype association studies based on genotype and phenotype network.
Published 2024-05-01“…Meanwhile, constructing a network based on associations between phenotypes and genotypes provides a new insight to analyze multiple phenotypes, which can explore whether phenotypes and genotypes might be related to each other at a higher level of cellular and organismal organization. …”
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A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes
Published 2010-01-01“…A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. …”
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Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.
Published 2013-01-01“…Mechanism-oriented phenotyping using collections of EMR-derived diagnoses can elucidate fundamental disease mechanisms.…”
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Multiple phenotypic domains of Fabry disease and their relevance for establishing genotype–phenotype correlations
Published 2019-03-01Subjects: Get full text
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A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes
Published 2010-04-01“…A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. …”
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Model-driven execution of phenotype algorithms – introduction of the Terminology- and Ontology-based Phenotyping Framework
Published 2023-11-01Subjects: “…phenotype…”
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Development of a deep-learning phenotyping tool for analyzing image-based strawberry phenotypes
Published 2024-07-01Subjects: Get full text
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Worm Phenotype Ontology: Integrating phenotype data within and beyond the <it>C. elegans </it>community
Published 2011-01-01“…The WPO is currently comprised of 1,880 phenotype terms, 74% of which have been used in the annotation of phenotypes associated with greater than 18,000 <it>C. elegans </it>genes. …”
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Topological Phenotypes Constitute a New Dimension in the Phenotypic Space of Leaf Venation Networks.
Published 2015-12-01“…This phenotypic trait encodes information orthogonal to widely used geometric phenotypic traits, and thus constitutes a new dimension in the leaf venation phenotypic space. …”
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