Measuring phenotype-phenotype similarity through the interactome by Jiajie Peng, Weiwei Hui, Xuequn Shang

Subjects: “…Phenotype relationships…”
Get full text

Severe asthma: how can we differentiate phenotypes? by R Louis

Subjects: “…Phenotypes…”
Get full text

Evolving the HDRUK Phenotype Library: Phenotype Creation and Editing by Daniel S Thayer, Jack Scanlon, Muhammad A Elmessary, Artur Zinnorov, Ieuan Scanlon, Alex Coldea, Hannah Davies, Carla Oliveira, Spiros Denaxas, Emily Jefferson, Harry Hemingway

“… Objective The HDRUK Phenotype Library (phenotypes.healthdatagateway.org) shares definitions used to measure concepts of interest (such as diagnoses or treatments) within health datasets. …”
Get full text

simplePHENOTYPES: SIMulation of pleiotropic, linked and epistatic phenotypes by Samuel B. Fernandes, Alexander E. Lipka

“…Abstract Background Advances in genotyping and phenotyping techniques have enabled the acquisition of a great amount of data. …”
Get full text

The Phenotyping Dilemma—The Challenges of a Diversified Phenotyping Community by Eva Rosenqvist, Dominik K. Großkinsky, Carl-Otto Ottosen, Rick van de Zedde

Subjects: “…phenotyping…”
Get full text

The Human Phenotype Ontology in 2024: phenotypes around the world by Gargano, MA, Matentzoglu, N, Coleman, B, Addo-Lartey, EB, Anagnostopoulos, A, Anderton, J, Avillach, P, Bagley, AM, Bakštein, E, Balhoff, JP, Baynam, G, Bello, SM, Berk, M, Bertram, H, Bishop, S, Blau, H, Bodenstein, DF, Botas, P, Boztug, K, Čady, J, Callahan, TJ, Cameron, R, Carbon, S, Castellanos, F, Sanders, SJ

“…The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. …”

Asthma phenotypes. by Pavord, I

“…The identification of phenotypes of asthma has a long history, but previous classifications have not identified clinically important differences in pathology, natural history, or treatment response. …”

Severe asthma phenotyping: does the definition of different phenotypes matter? by Marcia Margaret Menezes Pizzichini, José Eduardo Delfini Cançado

Get full text

Closing the phenotyping gap with non-invasive belowground field phenotyping by G. Blanchy, G. Blanchy, G. Blanchy, W. Deroo, T. De Swaef, P. Lootens, P. Quataert, I. Roldán-Ruíz, R. Versteeg, S. Garré

“…Whereas a number of techniques exist for aboveground field phenotyping, simultaneous non-invasive belowground phenotyping remains difficult. …”
Get full text

Phenotypic Definition and Genotype-Phenotype Correlates in PMPCA-Related Disease by Valentina Serpieri, Tommaso Biagini, Concetta Mazzotta, Rosa Pasquariello, Anna Rubegni, Filippo Santorelli, Gerardo Ongari, Silvia Cerri, Tommaso Mazza, Roberta Battini, Enza Maria Valente

“…Dynamics simulation of several <i>PMPCA</i> missense variants showed a variable impact on the flexibility of the glycine rich loop and, for some cases, on the overall protein stability, without clear genotype-phenotype correlates. Conclusion: We confirm the expansion of PMPCA phenotypic spectrum including an intermediate phenotype of progressive encephalopathy without systemic involvement. …”
Get full text

Testing the phenotypic gambit: phenotypic, genetic and environmental correlations of colour. by Hadfield, J, Nutall, A, Osorio, D, Owens, I

“…Evolutionary theory is primarily concerned with genetic processes, yet empirical testing of this theory often involves data collected on phenotypes. To make this tenable, the implicit assumption is often made that phenotypic patterns are good predictors of genetic patterns; an assumption that coined the phenotypic gambit. …”

Phenotypic equilibrium as probabilistic convergence in multi-phenotype cell population dynamics. by Da-Quan Jiang, Yue Wang, Da Zhou

“…We consider the cell population dynamics with n different phenotypes. Both the Markovian branching process model (stochastic model) and the ordinary differential equation (ODE) system model (deterministic model) are presented, and exploited to investigate the dynamics of the phenotypic proportions. …”
Get full text

Metabolic Phenotype of Daphnia Under Hypoxia: Macroevolution, Microevolution, and Phenotypic Plasticity by Tingyat M. Lee, Kurtis M. Westbury, Christopher J. Martyniuk, William A. Nelson, Christopher D. Moyes

Subjects: Get full text

Plant phenotype relationship corpus for biomedical relationships between plants and phenotypes by Hyejin Cho, Baeksoo Kim, Wonjun Choi, Doheon Lee, Hyunju Lee

Get full text

Next generation phenotyping for diagnosis and phenotype–genotype correlations in Kabuki syndrome by Quentin Hennocq, Marjolaine Willems, Jeanne Amiel, Stéphanie Arpin, Tania Attie-Bitach, Thomas Bongibault, Thomas Bouygues, Valérie Cormier-Daire, Pierre Corre, Klaus Dieterich, Maxime Douillet, Jean Feydy, Eva Galliani, Fabienne Giuliano, Stanislas Lyonnet, Arnaud Picard, Thantrira Porntaveetus, Marlène Rio, Flavien Rouxel, Vorasuk Shotelersuk, Annick Toutain, Kevin Yauy, David Geneviève, Roman H. Khonsari, Nicolas Garcelon

“…Abstract The field of dysmorphology has been changed by the use Artificial Intelligence (AI) and the development of Next Generation Phenotyping (NGP). The aim of this study was to propose a new NGP model for predicting KS (Kabuki Syndrome) on 2D facial photographs and distinguish KS1 (KS type 1, KMT2D-related) from KS2 (KS type 2, KDM6A-related). …”
Get full text

Multi-Phenotype Association Decomposition: Unraveling Complex Gene-Phenotype Relationships by Deborah Weighill, Deborah Weighill, Piet Jones, Piet Jones, Carissa Bleker, Carissa Bleker, Priya Ranjan, Priya Ranjan, Manesh Shah, Nan Zhao, Madhavi Martin, Stephen DiFazio, David Macaya-Sanz, Jeremy Schmutz, Jeremy Schmutz, Avinash Sreedasyam, Timothy Tschaplinski, Gerald Tuskan, Daniel Jacobson, Daniel Jacobson

Subjects: “…multi-phenotype associations…”
Get full text

Latent Space Phenotyping: Automatic Image-Based Phenotyping for Treatment Studies by Jordan Ubbens, Mikolaj Cieslak, Przemyslaw Prusinkiewicz, Isobel Parkin, Jana Ebersbach, Ian Stavness

“…In this work, we present Latent Space Phenotyping (LSP), a novel phenotyping method which is able to automatically detect and quantify response-to-treatment directly from images. …”
Get full text

Mortality in COPD patients according to clinical phenotypes by Golpe R, Suárez-Valor M, Martín-Robles I, Sanjuán-López P, Cano-Jiménez E, Castro-Añón O, Pérez de Llano LA

Subjects: Get full text

Phenotypes and Endotypes in Sarcoidosis: Unraveling Prognosis and Disease Course by Ilias C. Papanikolaou, Konstantinos Chytopoulos, Dimitrios Kaitatzis, Nikolaos Kostakis, Anastasios Bogiatzis, Paschalis Steiropoulos, Fotios Drakopanagiotakis

Subjects: Get full text

Identification of a hyperinflammatory sepsis phenotype using protein biomarker and clinical data in the ProCESS randomized trial by Kimberley M. DeMerle, Jason N. Kennedy, Chung-Chou H. Chang, Kevin Delucchi, David T. Huang, Max S. Kravitz, Nathan I. Shapiro, Donald M. Yealy, Derek C. Angus, Carolyn S. Calfee, Christopher W. Seymour

Subjects: Get full text