Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs by Khoo, Samuel Leon Juan

“…However, we were not able to detect Dishevelled 1 isoform at the protein level using the commercially available anti-Dishevelled 1 antibody; (2) different phenotypical changes were observed in cells transfected with siRNA targeting Dishevelled 1 and Dishevelled 2. …”
Get full text

Genetics and combining ability of corn (Zea mays L.) genotypes for forage utilization by Abu Sin, Maizura

“…Genetic distances among the inbred lines based on phenotypic and molecular characteristics were used to identify major heterotic groups and have revealed the presence of high level of genetic diversity among the inbred lines studied. …”
Get full text

Observations on the morphology of Australorbis nigricans by W. Lobato Paraense, Newton Deslandes

“…The morphological characteristics of the renal region and shell, and the great body length in the same condition of shell diameter, distinguish A. nigricans from the most related species A. glabratus, giving support to considering it a good species from a txonomic or phenotypic standpoint (morphospecies).<br>Foi feito um estudo morfológico do australorbis nigricans, baseado na observação da concha, da rádula, da região renal e da genitália de 50 espécimes com 18 mm de diâmetro. …”
Get full text

The impact of chronic kidney disease on stroke risk, mechanisms, and outcomes by Kelly, D

“…</p> <p>For the third part of my thesis, I focused on the relationship between CKD, subclinical cerebrovascular disease, and dementia in phenotyped cohorts within OXVASC. I investigated the age-specific associations of CKD and total SVD burden (total SVD score) adjusting for age, sex, and vascular risk factors in 1939 consecutive patients with TIA or ischaemic stroke who underwent cerebral magnetic resonance imaging (MRI) from 2004 to 2018. …”

Signatures of cellular immunity after vaccination and challenge that associate with clinical outcome of Salmonella Typhi infection by Cross, D

“…</p> <p>PBMCs where phenotyped by mass cytometry measuring 37 markers in total (n = 57 participants, protected: n = 28, diagnosed: n = 29). …”

Isolation and Identification of Aeromonas salmonicida from Thamnaconus septentrionalis and Sebastes schlegeli by Huaiyuan JIN, Yaokuan LIU, Ye GAO, Sudong XIA, Siqing CHEN, Zhaolan MO, Li BIAN, Jie LI

“…Based on the molecular analysis of 16S rRNA genes and Biolog Gen Ⅲ phenotype results, the isolates were identified as A. salmonicida. …”
Get full text

The mediating role of perceived social support from teacher in relation to dark tried personality, and social comparison with bullying behavior in females. by Arezoo Borukanlu, Farzaneh Mikaeli Manee

“…The essence of the triarchic model is that psychopathy encompasses three distinct phenotypic constructs: disinhibition which reflects a general propensity toward problems of impulse control; boldness, which is defined as the nexus of social dominance, emotional resiliency, and venturesomeness; and meanness, which is defined as aggressive resource seeking without regard for others (“disaffiliated agency”). …”
Get full text

Caracterización de la aloinmunización eritrocitaria en el Hospital Universitario del Valle entre 2011 y 2013 / Characterization of Red Blood Cells Alloimmunization at Hospital Univ... by José Arnulfo Pérez-Carrillo, Esp. MD., Armando Cortés-Buelvas, Esp. MD.

“…Results: Out of the eighty cases, 53.8 % were female and 46.2% were male. 65% were Hispanic and 35% African-American. 22.5% had a history of hematopoietic diseases and 45% were hospitalized for diagnoses included in this category of ICD-10. 79% of women had obstetric history. 18.75% were transfused previously. 36% of the cases had a CceeK- phenotype. 31.25% had alloantibody Anti-E followed by Anti-K 21.25%. …”
Get full text

The breeding biology of the Manx shearwater by Brooke, M

“…In the Manx Shearwater it appears that about three-quarters of the phenotypic variance of body size is due to genetic causes, and may therefore be inherited. …”

Selected Abstracts of the 19th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 18-21, 2023 by --- Various Authors

“…Bertino, A. Coscia ABS 20. PHENOTYPICAL EXPRESSION OF AHDC1 DE NOVO TRUNCANT MUTATIONS: A RARE DISEASE • B.M. …”
Get full text

Avant-propos by J. AGABRIEL, R. BAUMONT

“…Autant de propositions pour de nouvelles mesures de routine qui participeront à la détermination des nouveaux phénotypes. L’article de M. Doreau et al éclaire le débat sur l’empreinte environnementale de l’élevage allaitant en synthétisant les connaissances actuelles permettant d’établir le bilan de ses impacts positifs et négatifs. …”
Get full text

Rupture of dissection aneurysm of the vertebral artery followed by formation of epidural hematoma of the cervical spine: case report by Sergey A. Goroshchenko, Larisa V. Rozhchenko, Andrey E. Petrov, Natalia E. Ivanova, Aleksey Yu. Ivanov

“…In our case, the patient had no phenotypic characters of connective tissue dysplasia or genetic disposition to it. …”
Get full text

Evolutionary evaluation of the dominant genetic haplotype of SARS-CoV-2 virus in Iran from June to November 2020 by Shirin Jalili, Hadi Shirzad, Sadegh Salehi, Reza Mohammadi

“…Suggestions Due to the frequent changes in the virus genome and the possibility of creating new haplotypes with different phenotypic effects, it is suggested that the changes be examined periodically until the complete termination of the disease. …”
Get full text

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment by Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, Anja Urbach, Yuta Katayama, Akinobu Matsumoto, Keiichi I Nakayama, Shota Katori, Takuya Sato, Takuji Iwasato, Haruko Nakamura, Yoshio Goshima, Matthieu Raveau, Tetsuya Tatsukawa, Kazuhiro Yamakawa, Noriko Takahashi, Haruo Kasai, Johji Inazawa, Ikuo Nobuhisa, Tetsushi Kagawa, Tetsuya Taga, Mohamed Darwish, Hirofumi Nishizono, Keizo Takao, Kiran Sapkota, Kazutoshi Nakazawa, Tsuyoshi Takagi, Haruki Fujisawa, Yoshihisa Sugimura, Kyosuke Yamanishi, Lakshmi Rajagopal, Nanette Deneen Hannah, Herbert Y Meltzer, Tohru Yamamoto, Shuji Wakatsuki, Toshiyuki Araki, Katsuhiko Tabuchi, Tadahiro Numakawa, Hiroshi Kunugi, Freesia L Huang, Atsuko Hayata-Takano, Hitoshi Hashimoto, Kota Tamada, Toru Takumi, Takaoki Kasahara, Tadafumi Kato, Isabella A Graef, Gerald R Crabtree, Nozomi Asaoka, Hikari Hatakama, Shuji Kaneko, Takao Kohno, Mitsuharu Hattori, Yoshio Hoshiba, Ryuhei Miyake, Kisho Obi-Nagata, Akiko Hayashi-Takagi, Léa J Becker, Ipek Yalcin, Yoko Hagino, Hiroko Kotajima-Murakami, Yuki Moriya, Kazutaka Ikeda, Hyopil Kim, Bong-Kiun Kaang, Hikari Otabi, Yuta Yoshida, Atsushi Toyoda, Noboru H Komiyama, Seth GN Grant, Michiru Ida-Eto, Masaaki Narita, Ken-ichi Matsumoto, Emiko Okuda-Ashitaka, Iori Ohmori, Tadayuki Shimada, Kanato Yamagata, Hiroshi Ageta, Kunihiro Tsuchida, Kaoru Inokuchi, Takayuki Sassa, Akio Kihara, Motoaki Fukasawa, Nobuteru Usuda, Tayo Katano, Teruyuki Tanaka, Yoshihiro Yoshihara, Michihiro Igarashi, Takashi Hayashi, Kaori Ishikawa, Satoshi Yamamoto, Naoya Nishimura, Kazuto Nakada, Shinji Hirotsune, Kiyoshi Egawa, Kazuma Higashisaka, Yasuo Tsutsumi, Shoko Nishihara, Noriyuki Sugo, Takeshi Yagi, Naoto Ueno, Tomomi Yamamoto, Yoshihiro Kubo, Rie Ohashi, Nobuyuki Shiina, Kimiko Shimizu, Sayaka Higo-Yamamoto, Katsutaka Oishi, Hisashi Mori, Tamio Furuse, Masaru Tamura, Hisashi Shirakawa, Daiki X Sato, Yukiko U Inoue, Takayoshi Inoue, Yuriko Komine, Tetsuo Yamamori, Kenji Sakimura, Tsuyoshi Miyakawa

Get full text

Association of the rs5186 polymorphism of the AGTR1 gene with decreased eGFR in patients with type 2 diabetes from Mexico City by Manuel Alejandro Contreras Figueroa, Irene Mendoza Lujambio, Teresa Alvarado Gutiérrez, María Fernanda Pérez Hernández, Evelyn Yazmín Estrada Ramírez, Dominga Jiménez Guzmán, María Fernanda Lucas Sánchez, Hannia Fernanda González Morales, Héctor Jaime Gómez Samudio, Fernando Suarez Sánchez, Margarita Díaz Flores, Carlos Alberto Jiménez Zamarripa, Claudia Camelia Calzada Mendoza, María Esther Ocharán Hernández, Cora Mariana Orozco Velázquez, Mariana Soto Flores, Daniela Vicenta Hernández Orozco, Gabriela Yanet Cortés Moreno, Miguel Cruz, José de Jesús Peralta Romero

“…This disputable issue might be as a result of association studies in which many and varied clinical phenotypes included are contemplated as CKD inductors and enhancers. …”
Get full text

Asociación del polimorfismo rs5186 del gen AGTR1 con disminución de la TFGe en pacientes con diabetes tipo 2 de la Ciudad de México by Manuel Alejandro Contreras Figueroa, Irene Mendoza Lujambio, Teresa Alvarado Gutiérrez, María Fernanda Pérez Hernández, Evelyn Yazmín Estrada Ramírez, Dominga Jiménez Guzmán, María Fernanda Lucas Sánchez, Hannia Fernanda González Morales, Héctor Jaime Gómez Zamudio, Fernando Suarez Sánchez, Margarita Díaz Flores, Carlos Alberto Jiménez Zamarripa, Claudia Camelia Calzada Mendoza, María Esther Ocharán Hernández, Cora Mariana Orozco Velázquez, Mariana Soto Flores, Daniela Vicenta Hernández Orozco, Gabriela Yanet Cortés Moreno, Miguel Cruz, José de Jesús Peralta Romero

“…This disputable issue might be as a result of association studies in which many and varied clinical phenotypes included are contemplated as CKD inductors and enhancers. …”
Get full text

Brain Organoids, the Path Forward? by Ashley Diloreto

“…Currently, in the field of neurodegenerative diseases, many preclinical models fail to accurately represent the diseases they work with.[14] For instance, mouse models of Alzheimer's disease are genetically modified to overexpress high levels of human genetic mutations, however, the Alzheimer's phenotype is not expressed as expected.[15] Therefore, brain organoids have been considered the most ideal model for Alzheimer’s disease because they allow researchers to observe Aβ deposits, Tau tangles, and neuronal degeneration.[16] Brain organoids have been far more accurate representations than both the mice and two-dimensional neuron models.[17] In addition to Alzheimer’s studies, investigations about the Zika virus are better understood by examining the mechanisms in the brain organoids that resulted in microcephaly.[18] These studies more effectively capture the structure of the fetal brain during the first and second trimesters of pregnancy and more efficiently deconstruct the formation of microcephaly through the observation of neural progenitor cells and other cellular structures.[19] Furthermore, studying brain organoids enhances our understanding of human brain development in comparison to other hominid-like species, such as one of our closest relatives – Neanderthals. …”
Get full text

Dossier "PhénoFinlait : Phénotypage et génotypage pour la compréhension et la maîtrise de la composition fine du lait" by M. BROCHARD, K. DUHEN, D. BOICHARD

“…Par ailleurs, les équations produites permettent de déterminer le potentiel génétique d’un animal sans pour autant qu’il dispose lui-même (ou ses descendants) de phénotype mesuré (Robert-Granié et al 2011). L’un des enjeux en sélection est alors de concevoir et de mettre en œuvre des programmes de caractérisation phénotypique de populations de référence, ce que l’on a appelé des programmes de « phénotypage » à plus ou moins grande échelle. …”
Get full text

9Th International Congress of Medical Oncology & Hematology of Iran; 26-28 Nov., 2009 Olympic Hotel Tehran-Iran by A A

“…"n20 "n◘ "nImpact of Triple Negative Phenotype on Breast Cancer Epidemiology in Iran "nNajafi S., Mehrdad N., Olfatbakhsh A. …”
Get full text

The implications of competing risks and direct treatment disutility in cardiovascular disease and osteoporotic fracture: risk prediction and cost effectiveness analysis by Bruce Guthrie, Gabriel Rogers, Shona Livingstone, Daniel R Morales, Peter Donnan, Sarah Davis, Ji Hee Youn, Rob Hainsworth, Alexander Thompson, Katherine Payne

“…Consistent with previous studies, these findings suggest three distinct preference phenotypes: some people would avoid taking the medicines at all costs, some people see no problem with them and some people are willing to trade length of life to avoid treatment. …”
Get full text