Antigen Targeting of Porcine Skin DEC205⁺ Dendritic Cells by Edgar Alonso Melgoza-González, Mónica Reséndiz-Sandoval, Diana Hinojosa-Trujillo, Sofía Hernández-Valenzuela, Melissa García-Vega, Verónica Mata-Haro, Araceli Tepale-Segura, Laura C. Bonifaz, Armando Perez-Torres, Jesús Hernández

“…Furthermore, the cellular immune response was evaluated in pigs after intradermal application of the antigenized rAb ZH9F7 combined with porcine circovirus type 2 cap antigen (rAb ZH9F7-Cap). …”
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Cigarette smoke exposure induced animal models of COPD – procedural variations and apparatus by Urmila Manoj Aswar, Deepti Rai, Farheen Siddiqui, Subhash Laxmanrao Bodhankar, Prasad Thakurdesai

“…It was observed that mouse models are extensively used, C57B1/6 and BALB/c females are more vulnerable to COPD, whereas, in rat models, male SD rats are mostly used. Guinea pigs, due to their anatomical similarity, are found to be a better model that can be used to develop COPD. …”
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Steady-State Piperacillin Concentrations in the Proximity of an Orthopedic Implant: A Microdialysis Porcine Study by Johanne Gade Lilleøre, Andrea René Jørgensen, Martin Bruun Knudsen, Pelle Hanberg, Kristina Öbrink-Hansen, Sara Kousgaard Tøstesen, Kjeld Søballe, Maiken Stilling, Mats Bue

“…Time above the minimal inhibitory concentration (<i>f</i>T>MIC) was evaluated for MIC of 8 (low target) and 16 μg/mL (high target). Six female pigs received an intravenous bolus infusion of 4 g/0.5 g piperacillin/tazobactam over 30 min every 6 h. …”
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Determination of lethal electric field threshold for pulsed field ablation in ex vivo perfused porcine and human hearts by Bor Kos, Lars Mattison, David Ramirez, Helena Cindrič, Daniel C. Sigg, Paul A. Iaizzo, Mark T. Stewart, Damijan Miklavčič

“…These findings, albeit preliminary, from a limited number of hearts suggest that treatments in humans with parameters optimized in pigs should result in equal or greater lesions.…”
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Development of a quadruplex real-time quantitative RT-PCR for detection and differentiation of PHEV, PRV, CSFV, and JEV by Xin Hu, Shuping Feng, Kaichuang Shi, Kaichuang Shi, Yuwen Shi, Yanwen Yin, Feng Long, Xiankai Wei, Zongqiang Li

“…Porcine hemagglutinating encephalomyelitis virus (PHEV), porcine pseudorabies virus (PRV), classical swine fever virus (CSFV), and Japanese encephalitis virus (JEV) cause similar neurological symptoms in the infected pigs, and their differential diagnosis depends on laboratory testing. …”
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Determination of Optimal Antigen Yield and Virus Inactivation Conditions for the Production of the Candidate Foot-and-Mouth Disease Recombinant Vaccine Strain Asia1 Shamir-R in a B... by Jae Young Kim, Sun Young Park, Gyeongmin Lee, Sang Hyun Park, Jong-Sook Jin, Dohyun Kim, Jong-Hyeon Park, Seong-Yun Jeong, Young-Joon Ko

“…There was no antigen loss due to BEI treatment, and only a decrease in antigen levels was observed during storage. The sera from pigs immunized with antigen derived from a bioreactor exhibited a neutralizing antibody titer of approximately 1/1000 against Asia1 Shamir and Asia1/MOG/05 viruses; therefore, Asia1 Shamir-R is expected to provide sufficient protection against both viruses. …”
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Porcine Reproductive and Respiratory Syndrome Virus Modulates the Switch of Macrophage Polarization from M1 to M2 by Upregulating MoDC-Released sCD83 by Xingyu Gong, Tianyi Ma, Qiaoya Zhang, Yanhong Wang, Chengchuang Song, Min Lai, Chunlei Zhang, Xingtang Fang, Xi Chen

“…Porcine reproductive and respiratory syndrome virus (PRRSV), the most economically important infectious disease of pigs, elicits poor innate and adaptive immune responses. …”
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Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in <i>Culicoides sonorensis</i> Midges by Paula Rozo-Lopez, Steven J. Pauszek, Lauro Velazquez-Salinas, Luis L. Rodriguez, Yoonseong Park, Barbara S. Drolet

“…Thus, in addition to affecting virus-animal interactions, as seen with higher virulence in pigs, small genetic changes may also affect virus-vector interactions, contributing to the ability of specific viral lineages to escape endemic regions via vector-borne transmission.…”
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Development of a new multiplex quantitative PCR for the detection of Glaesserella parasuis, Mycoplasma hyorhinis, and Mycoplasma hyosynoviae by Simone Scherrer, Sarah Schmitt, Fenja Rademacher, Peter Kuhnert, Giovanni Ghielmetti, Sophie Peterhans, Roger Stephan

“…Moreover, a pilot study including different clinical specimens of 42 diseased pigs was performed. The specificity of the assay was 100% without cross‐reactivity or detection of other bacterial swine pathogens. …”
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<i>Cryptosporidium sciurinum</i> n. sp. (Apicomplexa: Cryptosporidiidae) in Eurasian Red Squirrels (<i>Sciurus vulgaris</i>) by Jitka Prediger, Jana Ježková, Nikola Holubová, Bohumil Sak, Roman Konečný, Michael Rost, John McEvoy, Dušan Rajský, Martin Kváč

“…Oocysts obtained from naturally-infected squirrels measured 5.54–5.22 μm and were not infectious for laboratory mice (BALB/c and SCID), Mongolian gerbils, Guinea pigs, Southern multimammate mice, chickens, or budgerigars. …”
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Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognize... by Marlene Mötz, Melissa R. Stas, Sabine E. Hammer, Tereza Duckova, Frederic Fontaine, Alexandra Kiesler, Kerstin Seitz, Andrea Ladinig, André C. Müller, Christiane Riedel, Armin Saalmüller, Till Rümenapf

“…Furthermore, we employed these identified peptides to stimulate peripheral blood mononuclear cells (PBMCs) of previously PRRSV-infected pigs and measured the PRRSV-specific CD8⁺ T-cell response with an intracellular cytokine staining (ICS). …”
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Automatic air volume control system for ventilation of two patients using a single ventilator: a large animal model study by Krzysztof Zieliński, Barbara Lisowska, Katarzyna Siewruk, Maria Sady, Karolina Ferenc, Maciej Barwijuk, Jarosław Olszewski, Krzysztof Anusz, Artur Jabłoński, Magdalena Gajewska, Piotr Okrzeja, Marcin Michnikowski, Dorota G. Pijanowska, Krzysztof Pluta, Elżbieta Remiszewska, Marek Darowski, Romuald Zabielski, Adam Liebert, Katarzyna Kramek-Romanowska, Anna Stecka, Maciej Kozarski, Raman Pasledni, Zdzisław Gajewski, Piotr Ładyżyński

“…We performed experiments with a total number of 16 animals. Eight pairs of pigs were ventilated by a ventilator or anesthetic machine and by Ventil for up to 27 h. …”
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Gut microbiota alteration with growth performance, histopathological lesions, and immune responses in Salmonella Typhimurium-infected weaned piglets by Seung-Won Yi, Han Gyu Lee, Eunju Kim, Young-Hun Jung, Eun-Yeong Bok, Ara Cho, Yoon Jung Do, Kyoung-Min So, Tai-Young Hur, Sang-Ik Oh

“…Typhimurium-infected weaned piglets. Ten 49-day-old pigs were divided into two groups: S. Typhimurium-inoculated (ST, n = 6) and negative control (NC, n = 4) groups. …”
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Lipid Exchange Factors at Membrane Contact Sites in African Swine Fever Virus Infection by Inmaculada Galindo, Miguel Ángel Cuesta-Geijo, Ana del Puerto, Eva Soriano, Covadonga Alonso

“…African swine fever (ASF) is a hemorrhagic fever of wild and domestic pigs with a high rate of mortality. Originally endemic in Africa, this disease is currently disseminating in Europe and China, causing a large socioeconomic impact. …”
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African Swine Fever Re-Emerging in Estonia: The Role of Seropositive Wild Boar from an Epidemiological Perspective by Katja Schulz, Jana Schulz, Christoph Staubach, Sandra Blome, Imbi Nurmoja, Franz J. Conraths, Carola Sauter-Louis, Arvo Viltrop

“…From February 2019 to August 2020, no pigs or wild boar tested positive for ASF virus (ASFV), only ASFV-specific antibodies could be detected in shot wild boar. …”
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<i>Streptococcus suis</i> Research Update: Serotype Prevalence and Antimicrobial Resistance Distribution in Swine Isolates Recovered in Spain from 2020 to 2022 by Máximo Petrocchi Rilo, César Bernardo Gutiérrez Martín, Vanessa Acebes Fernández, Álvaro Aguarón Turrientes, Alba González Fernández, Rubén Miguélez Pérez, Sonia Martínez Martínez

“…This study aimed to update the <i>Streptococcus suis</i> serotype distribution in Spain by analysing 302 clinical isolates recovered from diseased pigs between 2020 and 2022. The main objectives were to identify prevalent serotypes, differentiate specific serotypes 1, 14, 2, and 1/2, investigate specific genotypic and phenotypic antimicrobial resistance features, and explore associations between resistance genes and phenotypic resistances. …”
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The protective role of chicken cathelicidin-1 against Streptococcus suis serotype 2 in vitro and in vivo by Yi Lu, Fa Xiang, Liuyi Xu, Hongliang Tian, Qi Tao, Kaixiang Jia, Hang Yin, Chao Ye, Rendong Fang, Lianci Peng

“…The results show that CATH-1 exhibited a better bactericidal effect compared to other species’ cathelicidins including chickens (CATH-2, -3, and -B1), mice (CRAMP) and pigs (PMAP-36 and PR-39), which rapidly killed bacteria in 20 min by a time-killing curve assay. …”
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Characterization of a Read-through Fusion Transcript, BCL2L2-PABPN1, Involved in Porcine Adipogenesis by Jiyuan Zhu, Zewei Yang, Wanjun Hao, Jiaxin Li, Liang Wang, Jiqiao Xia, Dongjie Zhang, Di Liu, Xiuqin Yang

“…In this study, a <i>cis</i>-SAGe product, BCL2L2–PABPN1 (BP), was characterized in fat tissue of pigs with RT-PCR and RACE method. BP is an in-frame fusion product composed of 333 aa and all the functional domains of both parents. …”
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Evaluation of feasibility, efficiency and safety of a pure NOTES gastrojejunal bypass with gastric outlet obstruction, in an in vivo porcine model by J.-M. Gonzalez, E. A. Bonin, G. Vanbiervliet, E. Garnier, S. Berdah, K. Matthes, M. Barthet

“…These showed a significant difference in weight curves of a loss of 3.2 kg compared with gain of 5.2 kg in a control group. Four pigs died from anastomotic dehiscence complicated by peritonitis. …”
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The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure by Mendel Friedman, Alexander Xu, Rani Lee, Daniel N. Nguyen, Tina A. Phan, Sabrina M. Hamada, Rima Panchel, Christina C. Tam, Jong H. Kim, Luisa W. Cheng, Kirkwood M. Land

“…Plant-derived anthraquinones were evaluated in cell assays for their inhibitory activities against the parasitic protozoa <i>Trichomonas vaginalis</i> human strain G3 that causes the sexually transmitted disease trichomoniasis in women, <i>Tritrichomonas foetus</i> bovine strain D1 that causes sexually transmitted diseases in farm animals (bulls, cows, and pigs), <i>Tritrichomonas foetus</i>-like strain C1 that causes diarrhea in domestic animals (cats and dogs), and bacteria and fungi. …”
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