Inflammation-Induced Protein Unfolding in Airway Smooth Muscle Triggers a Homeostatic Response in Mitochondria by Debanjali Dasgupta, Philippe Delmotte, Gary C. Sieck

“…In our conceptual framework, we hypothesize that activation of these pathways is homeostatically directed towards mitochondrial remodeling via an increase in peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC1α) expression, which in turn triggers: (1) mitochondrial fragmentation (increased dynamin-related protein-1 (Drp1) and reduced mitofusin-2 (Mfn2) expression) and mitophagy (activation of the Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)/Parkin mitophagy pathway) to improve mitochondrial quality; (2) reduced Mfn2 also results in a disruption of mitochondrial tethering to the ER and reduced mitochondrial Ca²⁺ influx; and (3) mitochondrial biogenesis and increased mitochondrial volume density. …”
Get full text

Genomic Overlap between Platelet Parameters Variability and Age at Onset of Parkinson Disease by Alfonsina Tirozzi, Roberta Parisi, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Alessandro Gialluisi

“…The genes most significantly enriched for associations with PD-AAO included <i>ARHGEF3</i> (<i>Rho Guanine Nucleotide Exchange Factor 3</i>), previously associated with depression, and <i>KALRN</i> (<i>Kalirin RhoGEF Kinase</i>), encoding a PINK1 interactor previously implicated in schizophrenia, Alzheimer Disease and PD itself. …”
Get full text

Integrated genomic analysis defines molecular subgroups in dilated cardiomyopathy and identifies novel biomarkers based on machine learning methods by Ling-Fang Ye, Jia-Yi Weng, Li-Da Wu

“…We found that some of the gene modules (pink, black and grey) in WGCNA analysis were significantly related to cardiac function, and each molecular subgroup had its specific gene modules functions in modulating occurrence and progression of DCM. …”
Get full text

Three-dimensional endoscopic optical coherence tomography imaging of cervical inlet patch by Zhou, Chao, Kirtane, Tejas, Tsai, Tsung-Han, Lee, Hsiang-Chieh, Adler, Desmond C., Schmitt, Joseph, Huang, Qin, Fujimoto, James G., Mashimo, Hiroshi

“…During retraction of the endoscope, a pink circular lesion (A) was observed under white light endoscopy in the upper esophagus (spanning 20–22 cm from the incisors). …”
Get full text
Get full text
Get full text

Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy by Tan, Sijie, Yu, Chye Yun, Sim, Zhi Wei, Low, Zun Siong, Lee, Brianna, See, Faith, Min, Nyo, Gautam, Archana, Chu, Justin Jang Hann, Ng, Kee Woei, Wong, Esther

“…Upon onset of mitochondrial stress, PE further augments mitophagosome formation, and engages PINK1 and Parkin to the mitochondria to potentiate mitophagy. …”
Get full text
Get full text

Studies of networking algorithms in wireless sensor networks by Zhang, Pengfei

Get full text

KARAKTERISASI ISOLAT BAKTERI PEMBINTIL AKAR LEGUM DARI BEBERAPA AGROEKOSISTEM DI LAMPUNG BARAT by , PRENALY .A. AMALIA, , Ir. Sri Wedhastri, M.S.

“…When grown on medium Congo Red Yeast Mannitol Agar (CRYMA) showed 7 isolates were pink colour the same as Bradyrhizobium japonicum USDA122, and 3 isolates were white as well as Bradyrhizobium japonicum THA7. …”

The controversial role of ct angiogram in paediatric supracondylar humeral fracture with pulseless, perfused limb by Sharifudin, Mohd Ariff, Paiman, Mohammad, Wan Ismail, Wan Faisham Numan, Wan Sulaiman, Wan Azman, Sadagatullah, Abdul Nawfar, Mohd Shif, Mohd Shukrihizam

“…She had an impalpable radial pulse but her hand looked pink with a capillary refilling time of less than 2 seconds. …”
Get full text
Get full text
Get full text

Identification and characterisation of determinants of genome stability in response to a double-strand break by Kasparek, TR

“…Following break-induction, failed repair of the DSB leads to loss of the <em>ade6</em> allele, indicated by pink sectoring on low adenine plates. 39 sectoring hits were identified and further characterised to quantify levels of gene conversion via HR in response to a DSB, utilising Ch¹⁶<em>-RMYAH</em>. …”

BLUE CAP MOVEMENT® by Selvalingam, S., Azad Hassan, A.R., Lim, J.

“…It was founded in June 2015 with the motto \'Blue in Cap but Pink in Health\'. Our main partner is Malaysian Health Promotion Board (MySihat) under the Ministry of Health. …”
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text
Get full text

Prevalence and risk estimates of Cryptosporidium oocysts infection associated with consumption of raw-eaten vegetables in Maiduguri metropolis LGAs, Northeast Nigeria by Saidu, A. S., Mohammed, S., Adamu, S. G., Sadiq, M. A., Tijjani, A. O., Musa, H. I., Jajere, S. M., Goni, M. D., Muhammed, A., Idriss, M. D.

“…The oocysts were confirmed (100×) as bright pink spherules. Data generated were analyzed using IBM-SPSS V23.0, and p ≤ 0.05 was considered significant. …”

Treatment response of port-wine stain to 585-nm pulsed dye laser: a 5-year retrospective review by Shamsudin, Norashikin, Hemandas, Gangaram, Hussein, Suraiya H.

“…The site of lesion was mainly facial (34/36) with colour varying from red (24/36) to pink (4/36), dark purple (1/36) and mixed (7/36). …”
Get full text

Extraction and characterization of pectin from dragon fruit (Hylocereus polyrhizus) peel by Mohamad Zahari, Nur Izalin

“…Hunter L*, a*, and b* values of the DFP pectin were 39.95, 34.87 and 20.18, respectively, which showed the light pink color of the extracted pectin. DFP pectin demonstrated non-Newtonion, pseudoplastic characteristic at higher concentrations (2% and 3%) and exhibited several textural characteristics similar to that of citrus and apple pectins. …”

Cloning, characterization and expression of chicken (Gallus gallus Linnaeus) Bone Morphogenic Protein 2 in Pichia pastoris by Teh, Richard Swee Aun

“…The new BMP2 gene was then cloned into Pichia pink α-HC plasmid and relabeled as BMP2v2. The reduction of GC% also had direct impact on the annealing temperature of the primers set from 71.6oC reduced to 63oC and non-specific binding as well. …”
Get full text

Spectroscopic and magnetic studies of erbium doped phosphate glass embedded with natural ferrite oxide nanoparticles by Anigrahawati, Puzi

“…It was found that the color of the glass varies from pink (without natural Fe3O4 nanoparticles) to dark brown (2 mol% natural Fe3O4 nanoparticles). …”
Get full text

Effects of salpingitis simulation on the morphology and expression of inflammatory-related genes of oviduct in laying hens by L.L. Li, P.T. Xu, Z.P. Liu, C.A. Liu, X.Y. Dong, Z.F. Zhang, S.S. Guo, B.Y. Ding

“…A total of one hundred twenty 81-wk-old Roman Pink laying hens in good physical condition without the oviduct disease with an average egg production rate of 76% were fed a basal diet for 2 wks and then randomly allocated into 4 groups (6 replicates/group, 5 birds/replicate). …”
Get full text

Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress by Heejeong Kim, Byeong Tak Jeon, Isaac M. Kim, Sydney J. Bennett, Carolyn M. Lorch, Martonio Ponte Viana, Jacob F. Myers, Caroline J. Trupp, Zachary T. Whipps, Mondira Kundu, Soonkyu Chung, Xinghui Sun, Oleh Khalimonchuk, Jaekwon Lee, Seung-Hyun Ro

“…One well-established mechanism mediating selective removal of mitochondria under relatively mild mitochondria-depolarizing stress is PINK1-Parkin-mediated or ubiquitin-dependent mitophagy. …”
Get full text

Delving into the lifestyle of Sundarban Wetland resident, biofilm producing, halotolerant Salinicoccus roseus: a comparative genomics-based intervention by Bhramar Dutta, Urmi Halder, Annapurna Chitikineni, Rajeev K. Varshney, Rajib Bandopadhyay

“…Results Salinicoccus roseus strain RF1H is a pink-red pigmented, Gram-positive and non-motile cocci. …”
Get full text

Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway by Ying Liu, Yafang Li, Qinmei Tan, Yilin Lv, Yan Tang, Yue Yang, Xueqiong Yao, Fei Yang

“…Moreover, the protein expression levels of p-RAF/RAF, p-ERK1/2/ERK1/2, Pink1, Parkin, and LC3-II/LC-3-I were increased in the gastric tissue of mice exposed to 120 μg/L of MC-LR, while the protein expression level of P62 was significantly decreased. …”
Get full text

Characterization of volatiles in flowers from four Rosa chinensis cultivars by HS-SPME-GC × GC-QTOFMS by Wenxuan Quan, Jing Jin, Jing Jin, Chenyu Qian, Chaochan Li, Hongying Zhou

“…A total of 68, 78, 71, and 56 volatile compounds were identified in Rosa ‘Blue River’ (RBR), Rosa ‘Crimson Glory’ (RCG), Rosa ‘Pink Panther’ (RPP), and Rosa ‘Funkuhr’ (RF) samples, respectively. …”
Get full text