-
2881
Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells
Published 2023-07-01“…After using western blot and immunofluorescence to clarify the change of DRP1, we further examined MFF, PINK1, and PARKIN by western blot. We used cyclosporin A (CsA) to confirm the regulation of mitophagy and ceased the stretching as a rescue experiment. …”
Get full text
Article -
2882
Molecular mechanisms underlying selective clearance of protein aggregates and mitochondria by autophagy
Published 2017“…Upon mitochondrial stress, PE preserved the mitochondrial health, and protected the mitochondria against reactive oxygen species (ROS)-induced redox toxicity by promoting PINK1-Parkin mediated mitophagy. KD of TFEB abrogated mitophagy induction and the protective effects of PE on the mitochondria. …”
Get full text
Thesis -
2883
Biosynthesis of Poly (3-Hydroxybutyrate-Co-3-Hydroyvalerate) Copolymer from Organic Acids Using Comamonas sp. EB172
Published 2011“…The stained colonies containing PHA exhibited pink fluorescent colour when exposed under ultra violet (UV) light. …”
Get full text
Thesis -
2884
Optimization of spray drying process and storage stability of pitaya, Hylocereus polyrhizus (Weber) Britton & Rose pell powder.
Published 2011“…Spray dried pitaya peel powders were pink in color, high in betacyanin pigment retention, low in moisture content and had a water activity of 0.233-0.380. …”
Get full text
Thesis -
2885
Optimization of high performance liquid chromatography and PCR for determination of aflatoxin and ochratoxin a in peanuts
Published 2012“…Three-day-old purified green Aspergillus isolates grown at 30ºC on potato dextrose agar (PDA) plates were screened for their aflatoxin-producing ability using ammonia vapor. The pink/red color of colony reverse represented aflatoxin-producing strains. …”
Get full text
Thesis -
2886
The effect of silver and gold nanoparticles on optical properties of europium-doped magnesium-zinc-sulfophosphate glass system
Published 2020“…Three series of europium doped magnesium zinc sulfophosphate glasses co-embedded with silver and gold nanoparticles of composition 65P2O5-20MgO-15ZnSO4–(x)Eu2O3with 0 ≤ x ≤ 2.0 mol%, 63.5P2O5-20MgO-15ZnSO4–1.5Eu2O3–(y)AgCl with 0.1 ≤ y ≤ 1.1 grams and 63.5P2O5-20MgO-15ZnSO4–1.5Eu2O3–0.9gAg–(z)Au with 0.05 ≤ z ≤ 0.30 grams in excess were prepared using melt quenching technique. Pink samples were obtained. The existence of broad hump in X-ray diffraction (XRD) pattern verifies the amorphous nature of glasses. …”
Get full text
Thesis -
2887
Composição físico-química de carcaças de bezerros holandeses alimentados após o desaleitamento com silagem de grãos úmidos ou grãos secos de milho ou sorgo Physical and chemical ca...
Published 2008-01-01“…<br>The physical and chemical carcasses composition of calves fed after weaning until slaughter with high moisture grains silage or dry ground grains of corn or sorghum was evaluated, for production of pink meat veal. Thirty Holstein calves were alloted to a complete randomized blocks experimental design with five blocks and six concentrate rations with similar contents of protein (18.5% CP) and energy (3.2 Mcal ME/kg DM), formulated with dry ground corn (GC), high moisture corn silage (HMCS), dry ground sorghum with tannin (GSWT), high moisture whole sorghum with tannin silage (HMWSWTS), dry ground sorghum without tannin (GSWTT) or high moisture whole sorghum without tannin silage (HMWSWTTS). …”
Get full text
Article -
2888
Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients
Published 2022-06-01“…Mitochondrial fission is a prerequisite for mitophagy activation, and no variation was found in either key markers of mitochondrial fission (Fis1 and DRP1) or mitophagy (Parkin, PINK1, and Mul1). Two contradictory hypotheses arise from these results: defective mitophagy, which probably increases the number of damaged and fragmented mitochondria, or a relative increase in mitophagy through elevated mitophagic potential (Parkin/VDAC ratio; +176.4%; P < 0.02). …”
Get full text
Article -
2889
Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes
Published 2023-03-01“…Data illustrated that exposure to BPA enhanced autophagy (ULK1, Beclin-1, LC3, Parkin, and PINK1), ERS (GRP78, CHOP10, ATF4, and ATF6) and apoptosis (Caspase 3, Bcl-2, Bax, P53) but decreased the antioxidant (CAT, Nrf2, HO-1, and NQO1)-related mRNA and protein expressions as well as impaired the mitochondrial function. …”
Get full text
Article -
2890
Assessing the Neurotoxicity of a Sub-Optimal Dose of Rotenone in Zebrafish (<i>Danio rerio</i>) and the Possible Neuroactive Potential of Valproic Acid, Combination of Levodopa and...
Published 2022-10-01“…ROT causes significant changes in the central nervous system (CNS), notably reduced neurogenesis and angiogenesis, by triggering apoptosis, reflected by the increased expression of <i>PARKIN</i> and <i>PINK1</i> gene(s), low brain dopamine (DA) levels, and as opposed to <i>LRRK2</i> and <i>SNCA</i> compared with healthy zebrafish. …”
Get full text
Article -
2891
Gene coexpression analysis reveals key pathways and hub genes related to late-acting self-incompatibility in Camellia oleifera
Published 2023-01-01“…Genes in the blue module (1163 genes) were positively correlated with FSR, and genes in the pink module (339 genes) were negatively correlated with FSR. …”
Get full text
Article -
2892
Observations on the morphology of Pomacea lineata (Spix, 1827) (Mollusca, Ampullariidae) Observações sobre a morfologia de Pomacea lineata (Spix, 1827) (Mollusca, Ampullaridae)
Published 1987-12-01“…Seminal receptalble tubiform, thick-walled and rounded proximally. Albumen gland large, pink, enclosing the receptacle and the spiral capsule gland. …”
Get full text
Article -
2893
Identification of crucial modules and genes associated with backfat tissue development by WGCNA in Ningxiang pigs
Published 2023-08-01“…A total of 1,024 DEGs were identified in five comparison groups (120 days vs. 60 days, 180 days vs. 120 days, 240 days vs. 180 days, 300 days vs. 240 days, and 360 days vs. 300 days). The turquoise, red, pink, paleturquoise, darkorange, and darkgreen module had the highest correlation coefficient with 60, 120, 180, 240, 300, and 360 days developmental stage, while the tan, black and turquoise module had strong relationship with backfat thickness, adipocyte area, and adipocyte number, respectively. …”
Get full text
Article -
2894
Protective effects of selenized yeast on the combination of cadmium-, lead-, mercury-, and chromium-induced toxicity in laying hens
Published 2022-09-01“…A total of 160 Lohmann pink-shell laying hens (63-week-old) were randomly divided into four treatments with 10 replicates of four hens each. …”
Get full text
Article -
2895
Examining the utility of near infrared light as pre-exposure therapy to mitigate temporary noise-induced hearing loss in humans
Published 2024-04-01“…IntroductionThis study sought to determine the effect of Occupational Safety and Health Administration (OSHA) compliant noise on auditory health and assess whether pre-noise near infrared (NIR) light therapy can mitigate the effects of noise exposure.MethodsOver four visits, participants (n = 30, NCT#: 03834714) with normal hearing completed baseline hearing health assessments followed by exposure to open ear, continuous pink noise at 94 dBA for 15 min. Immediately thereafter, post-noise hearing tests at 3000, 4000, and 6000 Hz and distortion product otoacoustic emissions (DPOAEs) were conducted along with the Modified Rhyme Test (MRT), Masking Level Difference Test (MLD), and Fixed Level Frequency Tests (FLFT) [collectively referred to as the Central and Peripheral Auditory Test Battery (CPATB)] to acquire baseline noise sensitivity profiles. …”
Get full text
Article -
2896
The improving effect of soybean isoflavones on ovarian function in older laying hens
Published 2023-10-01“…A total of 160 Lohmann pink layers (66-wk-old) were used in a 2 × 2 factorial design, which included 2 egg-laying levels [low (76.89 ± 1.65%; LOW) and normal (84.96 ± 1.01%; NOR)] and 2 different dietary groups [0 mg/kg SF, 20 mg/kg SF] were used. …”
Get full text
Article -
2897
Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats
Published 2023-02-01“…Western blot assay was used to detect the protein expressions of SOD1, SOD2, catalase (CAT), hypoxia-inducible factor (HIF)-1α, vascular endothelial growth factor (VEGF), occludin, E-cadherin, bcl-xl, LC 3, Beclin 1, PTEN-induced putative kinase 1 (PINK 1) and Parkin. Results The histopathological examination demonstrated that chlorine could destroy the lung structure with hemorrhage, alveolar collapse, and inflammatory infiltration. …”
Get full text
Article -
2898
Generation of purple-violet chrysanthemums via anthocyanin B-ring hydroxylation and glucosylation introduced from Osteospermum hybrid F3'5'H and Clitoria ternatea A3'5'GT
Published 2021-01-01“…Among the F3'5'H transgenic lines, those overexpressing endogenous CmF3'Hm could not generate blue flower color, although red color was changed to light pink due to CtA3'5'GT function. Meanwhile, OhF3'5'H introduction promoted the accumulation of delphinidin and its derivatives in chrysanthemum, changing the flower color from red-purple to purple-violet. …”
Get full text
Article -
2899
Clinical and Genetic Analysis of Costa Rican Patients With Parkinson's Disease
Published 2021-08-01“…We sequenced coding and untranslated regions in familial PD and atypical parkinsonism-associated genes including GBA, SNCA, VPS35, LRRK2, GCH1, PRKN, PINK1, DJ-1, VPS13C, and ATP13A2.Results: Mean age of PD probands was 62.12 ± 13.51 years; 57.6% were male. …”
Get full text
Article -
2900
Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs
Published 2023-01-01“…In GSCs, mitofission (Drp1) or mitophagy (Pink1/Parkin) genes are essential to enter quiescence, whereas mitochondrial biogenesis (PGC1α) or fusion (Mfn2) genes are crucial for exiting quiescence. …”
Get full text
Article