Mechanical force induces mitophagy-mediated anaerobic oxidation in periodontal ligament stem cells by Zijie Zhang, Shuyue Cui, Yajing Fu, Jixiao Wang, Jiani Liu, Fulan Wei

“…After using western blot and immunofluorescence to clarify the change of DRP1, we further examined MFF, PINK1, and PARKIN by western blot. We used cyclosporin A (CsA) to confirm the regulation of mitophagy and ceased the stretching as a rescue experiment. …”
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Molecular mechanisms underlying selective clearance of protein aggregates and mitochondria by autophagy by Tan, Sijie

“…Upon mitochondrial stress, PE preserved the mitochondrial health, and protected the mitochondria against reactive oxygen species (ROS)-induced redox toxicity by promoting PINK1-Parkin mediated mitophagy. KD of TFEB abrogated mitophagy induction and the protective effects of PE on the mitochondria. …”
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Biosynthesis of Poly (3-Hydroxybutyrate-Co-3-Hydroyvalerate) Copolymer from Organic Acids Using Comamonas sp. EB172 by Zakaria @ Mamat, Mohd Rafein

“…The stained colonies containing PHA exhibited pink fluorescent colour when exposed under ultra violet (UV) light. …”
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Optimization of spray drying process and storage stability of pitaya, Hylocereus polyrhizus (Weber) Britton & Rose pell powder. by Ee, Shu Chee

“…Spray dried pitaya peel powders were pink in color, high in betacyanin pigment retention, low in moisture content and had a water activity of 0.233-0.380. …”
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Optimization of high performance liquid chromatography and PCR for determination of aflatoxin and ochratoxin a in peanuts by Afsah Hejri, Leili

“…Three-day-old purified green Aspergillus isolates grown at 30ºC on potato dextrose agar (PDA) plates were screened for their aflatoxin-producing ability using ammonia vapor. The pink/red color of colony reverse represented aflatoxin-producing strains. …”
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The effect of silver and gold nanoparticles on optical properties of europium-doped magnesium-zinc-sulfophosphate glass system by Mohammed Danmallam, Ibrahim

“…Three series of europium doped magnesium zinc sulfophosphate glasses co-embedded with silver and gold nanoparticles of composition 65P2O5-20MgO-15ZnSO4–(x)Eu2O3with 0 ≤ x ≤ 2.0 mol%, 63.5P2O5-20MgO-15ZnSO4–1.5Eu2O3–(y)AgCl with 0.1 ≤ y ≤ 1.1 grams and 63.5P2O5-20MgO-15ZnSO4–1.5Eu2O3–0.9gAg–(z)Au with 0.05 ≤ z ≤ 0.30 grams in excess were prepared using melt quenching technique. Pink samples were obtained. The existence of broad hump in X-ray diffraction (XRD) pattern verifies the amorphous nature of glasses. …”
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Composição físico-química de carcaças de bezerros holandeses alimentados após o desaleitamento com silagem de grãos úmidos ou grãos secos de milho ou sorgo Physical and chemical ca... by Gercílio Alves de Almeida Júnior, Ciniro Costa, Sebastião Marcos Ribeiro de Carvalho, Pedro Persichetti Júnior, Amanda Panichi

“…<br>The physical and chemical carcasses composition of calves fed after weaning until slaughter with high moisture grains silage or dry ground grains of corn or sorghum was evaluated, for production of pink meat veal. Thirty Holstein calves were alloted to a complete randomized blocks experimental design with five blocks and six concentrate rations with similar contents of protein (18.5% CP) and energy (3.2 Mcal ME/kg DM), formulated with dry ground corn (GC), high moisture corn silage (HMCS), dry ground sorghum with tannin (GSWT), high moisture whole sorghum with tannin silage (HMWSWTS), dry ground sorghum without tannin (GSWTT) or high moisture whole sorghum without tannin silage (HMWSWTTS). …”
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Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients by Joris Mallard, Elyse Hucteau, Anne‐Laure Charles, Laura Bender, Claire Baeza, Mathilde Pélissie, Philippe Trensz, Carole Pflumio, Michal Kalish‐Weindling, Bernard Gény, Roland Schott, Fabrice Favret, Xavier Pivot, Thomas J. Hureau, Allan F. Pagano

“…Mitochondrial fission is a prerequisite for mitophagy activation, and no variation was found in either key markers of mitochondrial fission (Fis1 and DRP1) or mitophagy (Parkin, PINK1, and Mul1). Two contradictory hypotheses arise from these results: defective mitophagy, which probably increases the number of damaged and fragmented mitochondria, or a relative increase in mitophagy through elevated mitophagic potential (Parkin/VDAC ratio; +176.4%; P < 0.02). …”
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Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes by Hao Zhang, Yi Zheng, Xiaoyun Liu, Xia Zha, Mabrouk Elsabagh, Yi Ma, Honghua Jiang, Hongrong Wang, Mengzhi Wang

“…Data illustrated that exposure to BPA enhanced autophagy (ULK1, Beclin-1, LC3, Parkin, and PINK1), ERS (GRP78, CHOP10, ATF4, and ATF6) and apoptosis (Caspase 3, Bcl-2, Bax, P53) but decreased the antioxidant (CAT, Nrf2, HO-1, and NQO1)-related mRNA and protein expressions as well as impaired the mitochondrial function. …”
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Assessing the Neurotoxicity of a Sub-Optimal Dose of Rotenone in Zebrafish (<i>Danio rerio</i>) and the Possible Neuroactive Potential of Valproic Acid, Combination of Levodopa and... by Ovidiu-Dumitru Ilie, Raluca Duta, Ioana-Miruna Balmus, Alexandra Savuca, Adriana Petrovici, Ilinca-Bianca Nita, Lucian-Mihai Antoci, Roxana Jijie, Cosmin-Teodor Mihai, Alin Ciobica, Mircea Nicoara, Roxana Popescu, Romeo Dobrin, Carmen Solcan, Anca Trifan, Carol Stanciu, Bogdan Doroftei

“…ROT causes significant changes in the central nervous system (CNS), notably reduced neurogenesis and angiogenesis, by triggering apoptosis, reflected by the increased expression of <i>PARKIN</i> and <i>PINK1</i> gene(s), low brain dopamine (DA) levels, and as opposed to <i>LRRK2</i> and <i>SNCA</i> compared with healthy zebrafish. …”
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Gene coexpression analysis reveals key pathways and hub genes related to late-acting self-incompatibility in Camellia oleifera by Chang Li, Chang Li, Yi Long, Yi Long, Mengqi Lu, Mengqi Lu, Junqin Zhou, Junqin Zhou, Sen Wang, Sen Wang, Yan Xu, Yan Xu, Xiaofeng Tan, Xiaofeng Tan

“…Genes in the blue module (1163 genes) were positively correlated with FSR, and genes in the pink module (339 genes) were negatively correlated with FSR. …”
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Observations on the morphology of Pomacea lineata (Spix, 1827) (Mollusca, Ampullariidae) Observações sobre a morfologia de Pomacea lineata (Spix, 1827) (Mollusca, Ampullaridae) by Silvana Carvalho Thiengo

“…Seminal receptalble tubiform, thick-walled and rounded proximally. Albumen gland large, pink, enclosing the receptacle and the spiral capsule gland. …”
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Identification of crucial modules and genes associated with backfat tissue development by WGCNA in Ningxiang pigs by Chen Chen, Huibo Ren, Huali Li, Yuan Deng, Qingming Cui, Ji Zhu, Siyang Zhang, Jine Yu, Huiming Wang, Xiaodan Yu, Shiliu Yang, Xionggui Hu, Yinglin Peng, Yinglin Peng

“…A total of 1,024 DEGs were identified in five comparison groups (120 days vs. 60 days, 180 days vs. 120 days, 240 days vs. 180 days, 300 days vs. 240 days, and 360 days vs. 300 days). The turquoise, red, pink, paleturquoise, darkorange, and darkgreen module had the highest correlation coefficient with 60, 120, 180, 240, 300, and 360 days developmental stage, while the tan, black and turquoise module had strong relationship with backfat thickness, adipocyte area, and adipocyte number, respectively. …”
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Protective effects of selenized yeast on the combination of cadmium-, lead-, mercury-, and chromium-induced toxicity in laying hens by Caimei Wu, Jingping Song, Lang Li, Yuxuan Jiang, Todd J. Applegate, Bing Wu, Guangmang Liu, Jianping Wang, Yan Lin, Keying Zhang, Hua Li, Fali Wu, Shiping Bai

“…A total of 160 Lohmann pink-shell laying hens (63-week-old) were randomly divided into four treatments with 10 replicates of four hens each. …”
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Examining the utility of near infrared light as pre-exposure therapy to mitigate temporary noise-induced hearing loss in humans by Erin Williams, Erin Williams, Erin Williams, Kayla Minesinger, Kayla Minesinger, Hilary Gallagher, J. R. Stefanson, Nathaniel Bridges, Natalie Jackson, Valerie Stark, Jennifer Coto, Suhrud Rajguru, Suhrud Rajguru, Kurt Yankaskas, Rick Rogers, Michael E. Hoffer, Michael E. Hoffer

“…IntroductionThis study sought to determine the effect of Occupational Safety and Health Administration (OSHA) compliant noise on auditory health and assess whether pre-noise near infrared (NIR) light therapy can mitigate the effects of noise exposure.MethodsOver four visits, participants (n = 30, NCT#: 03834714) with normal hearing completed baseline hearing health assessments followed by exposure to open ear, continuous pink noise at 94 dBA for 15 min. Immediately thereafter, post-noise hearing tests at 3000, 4000, and 6000 Hz and distortion product otoacoustic emissions (DPOAEs) were conducted along with the Modified Rhyme Test (MRT), Masking Level Difference Test (MLD), and Fixed Level Frequency Tests (FLFT) [collectively referred to as the Central and Peripheral Auditory Test Battery (CPATB)] to acquire baseline noise sensitivity profiles. …”
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The improving effect of soybean isoflavones on ovarian function in older laying hens by Taoyan Qiang, Jianping Wang, Xuemei Ding, Qiufeng Zeng, Shiping Bai, Li Lv, Yue Xuan, Huanwei Peng, Keying Zhang

“…A total of 160 Lohmann pink layers (66-wk-old) were used in a 2 × 2 factorial design, which included 2 egg-laying levels [low (76.89 ± 1.65%; LOW) and normal (84.96 ± 1.01%; NOR)] and 2 different dietary groups [0 mg/kg SF, 20 mg/kg SF] were used. …”
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Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats by Meng-meng Liu, Jiang-zheng Liu, Chen-qian Zhao, Peng Guo, Zhao Wang, Hao Wu, Weihua Yu, Rui Liu, Chun-xu Hai, Xiao-di Zhang

“…Western blot assay was used to detect the protein expressions of SOD1, SOD2, catalase (CAT), hypoxia-inducible factor (HIF)-1α, vascular endothelial growth factor (VEGF), occludin, E-cadherin, bcl-xl, LC 3, Beclin 1, PTEN-induced putative kinase 1 (PINK 1) and Parkin. Results The histopathological examination demonstrated that chlorine could destroy the lung structure with hemorrhage, alveolar collapse, and inflammatory infiltration. …”
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Generation of purple-violet chrysanthemums via anthocyanin B-ring hydroxylation and glucosylation introduced from Osteospermum hybrid F3'5'H and Clitoria ternatea A3'5'GT by Xiaoying Han, Yuting Luo, Jiaoyang Lin, Huiying Wu, Hao Sun, Lijie Zhou, Sumei Chen, Zhiyong Guan, Weimin Fang, Fei Zhang, Fadi Chen, Jiafu Jiang

“…Among the F3'5'H transgenic lines, those overexpressing endogenous CmF3'Hm could not generate blue flower color, although red color was changed to light pink due to CtA3'5'GT function. Meanwhile, OhF3'5'H introduction promoted the accumulation of delphinidin and its derivatives in chrysanthemum, changing the flower color from red-purple to purple-violet. …”
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Clinical and Genetic Analysis of Costa Rican Patients With Parkinson's Disease by Gabriel Torrealba-Acosta, Gabriel Torrealba-Acosta, Eric Yu, Eric Yu, Tanya Lobo-Prada, Tanya Lobo-Prada, Javier Ruíz-Martínez, Javier Ruíz-Martínez, Javier Ruíz-Martínez, Ana Gorostidi-Pagola, Ana Gorostidi-Pagola, Ana Gorostidi-Pagola, Ziv Gan-Or, Ziv Gan-Or, Ziv Gan-Or, Kenneth Carazo-Céspedes, Jean-François Trempe, Ignacio F. Mata, Jaime Fornaguera-Trías, Jaime Fornaguera-Trías

“…We sequenced coding and untranslated regions in familial PD and atypical parkinsonism-associated genes including GBA, SNCA, VPS35, LRRK2, GCH1, PRKN, PINK1, DJ-1, VPS13C, and ATP13A2.Results: Mean age of PD probands was 62.12 ± 13.51 years; 57.6% were male. …”
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Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs by Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker

“…In GSCs, mitofission (Drp1) or mitophagy (Pink1/Parkin) genes are essential to enter quiescence, whereas mitochondrial biogenesis (PGC1α) or fusion (Mfn2) genes are crucial for exiting quiescence. …”
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